HAUS8 and ZG16B

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		HAUS8	ZG16B
Description		HAUS augmin like complex subunit 8	zymogen granule protein 16B
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GO Annotations	Cellular Component	Spindle Pole Cytoplasm Centrosome Spindle Cytosol Cytoskeleton Microtubule Nuclear Microtubule HAUS Complex Mitotic Spindle Microtubule	Extracellular Region Extracellular Space Cytoplasm Plasma Membrane Membrane Apicolateral Plasma Membrane Extracellular Exosome
	Molecular Function	Protein Binding Microtubule Binding	Protein Binding Carbohydrate Binding
	Biological Process	Centrosome Cycle Regulation Of Microtubule Nucleation Spindle Assembly Cell Division	Cell Migration
Pathways		Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2
Drugs
Diseases
GWAS		Mean corpuscular hemoglobin concentration ( 32888494) Mosquito bite size ( 28199695) Selective IgA deficiency ( 27723758) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)	Blood protein levels ( 30072576)
Interacting Genes		14 interacting genes: APP C1orf216 CCHCR1 DEUP1 HAUS6 HSPB1 NME7 NRDE2 NTAQ1 NUP54 OGT TXN2 USHBP1 ZG16B	10 interacting genes: GOLGA2 HAUS8 NEIL3 PNMA1 SGTA SGTB UBAC1 UBQLN1 UBQLN2 UBQLN4
Entrez ID		93323	124220
HPRD ID		11318	14024
Ensembl ID		ENSG00000131351	ENSG00000162078
Uniprot IDs		Q9BT25	A0A0C4DGN4 G8H6I3 Q96DA0
PDB IDs		7SQK	3AQG
Enriched GO Terms of Interacting Partners?		Amyloid-beta Complex Growth Cone Lamellipodium Cytoskeleton-dependent Intracellular Transport Regulation Of Response To Calcium Ion Regulation Of Glycolytic Process Microtubule-based Transport Transport Along Microtubule Amylin Binding Positive Regulation Of Toll Signaling Pathway Microtubule-based Process Negative Regulation Of Protein Kinase C Signaling Spindle Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Regulation Of Microtubule Nucleation Protein-N-terminal Glutamine Amidohydrolase Activity	Polyubiquitin Modification-dependent Protein Binding Positive Regulation Of ERAD Pathway TRC Complex Regulation Of ERAD Pathway Positive Regulation Of Response To Endoplasmic Reticulum Stress Regulation Of Proteasomal Protein Catabolic Process Autophagosome Regulation Of Response To Endoplasmic Reticulum Stress Post-translational Protein Targeting To Endoplasmic Reticulum Membrane ERAD Pathway Positive Regulation Of Proteasomal Protein Catabolic Process Regulation Of Autophagy Regulation Of Protein Catabolic Process Regulation Of Proteolysis Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Protein Targeting To ER Identical Protein Binding Regulation Of Cellular Response To Stress Establishment Of Protein Localization To Endoplasmic Reticulum Regulation Of Macroautophagy Positive Regulation Of Proteolysis Positive Regulation Of Protein Catabolic Process Response To Endoplasmic Reticulum Stress Centrosome Cycle Proteolysis Involved In Protein Catabolic Process Organelle Assembly Autophagy Negative Regulation Of Store-operated Calcium Channel Activity MCM Complex Binding Nuclear Microtubule Protein Targeting To Membrane Positive Regulation Of Protein Metabolic Process Regulation Of Protein Metabolic Process Microtubule Organizing Center Organization Negative Regulation Of Catabolic Process Cellular Response To Stress Negative Regulation Of G Protein-coupled Receptor Internalization Nuclear Proteasome Complex Spindle Assembly Autophagosome Assembly Autophagosome Organization Negative Regulation Of Autophagy Negative Regulation Of Toll-like Receptor 3 Signaling Pathway Negative Regulation Of Autophagosome Maturation Macromolecule Catabolic Process Positive Regulation Of Protein Glycosylation BAT3 Complex Binding Proteasomal Protein Catabolic Process Negative Regulation Of Clathrin-dependent Endocytosis Depurination
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