HAUS8 and DEUP1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		HAUS8	DEUP1
Description		HAUS augmin like complex subunit 8	deuterosome assembly protein 1
Image			No pdb structure
GO Annotations	Cellular Component	Spindle Pole Cytoplasm Centrosome Spindle Cytosol Cytoskeleton Microtubule Nuclear Microtubule HAUS Complex Mitotic Spindle Microtubule	Cytoplasm Centriole Deuterosome
	Molecular Function	Protein Binding Microtubule Binding	Protein Binding Identical Protein Binding
	Biological Process	Centrosome Cycle Regulation Of Microtubule Nucleation Spindle Assembly Cell Division	Centriole Replication Cell Projection Organization De Novo Centriole Assembly Involved In Multi-ciliated Epithelial Cell Differentiation Multi-ciliated Epithelial Cell Differentiation
Pathways		Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2
Drugs
Diseases
GWAS		Mean corpuscular hemoglobin concentration ( 32888494) Mosquito bite size ( 28199695) Selective IgA deficiency ( 27723758) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		14 interacting genes: APP C1orf216 CCHCR1 DEUP1 HAUS6 HSPB1 NME7 NRDE2 NTAQ1 NUP54 OGT TXN2 USHBP1 ZG16B	44 interacting genes: AMPH ARL16 BRMS1L CCDC187 CCDC85B CCHCR1 CEP57 DGCR6 DGCR6L DTNB ESRRG EXOC5 FAM50B FBF1 GEM GOLGA2 HAUS8 HGS IFIT3 ING5 KCTD9 KIFC3 KRT15 KRT28 KRT3 LNX1 NTAQ1 PIAS2 PPP1R13B RUNX1T1 SKIL SUMO1 TBC1D22B TFPT TRIM54 TXLNA TXLNB USHBP1 ZFHX3 ZNF148 ZNF460 ZNF572 ZNF655 ZNF835
Entrez ID		93323	159989
HPRD ID		11318	08689
Ensembl ID		ENSG00000131351	ENSG00000165325
Uniprot IDs		Q9BT25	E9PLX9 Q05D60
PDB IDs		7SQK
Enriched GO Terms of Interacting Partners?		Amyloid-beta Complex Growth Cone Lamellipodium Cytoskeleton-dependent Intracellular Transport Regulation Of Response To Calcium Ion Regulation Of Glycolytic Process Microtubule-based Transport Transport Along Microtubule Amylin Binding Positive Regulation Of Toll Signaling Pathway Microtubule-based Process Negative Regulation Of Protein Kinase C Signaling Spindle Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Regulation Of Microtubule Nucleation Protein-N-terminal Glutamine Amidohydrolase Activity	Microtubule Binding Keratin Filament
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