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USH1G and PRKAA2
Number of citations of the paper that reports this interaction (PubMedID
32296183
)
50
Data Source:
BioGRID
(two hybrid)
USH1G
PRKAA2
Description
USH1 protein network component sans
protein kinase AMP-activated catalytic subunit alpha 2
Image
GO Annotations
Cellular Component
Photoreceptor Inner Segment
Nucleus
Cytoplasm
Centrosome
Cytosol
Cytoskeleton
Plasma Membrane
Cilium
Cajal Body
Actin Cytoskeleton
Membrane
Nuclear Speck
Photoreceptor Connecting Cilium
Ciliary Basal Body
Cell Projection
Ciliary Base
Photoreceptor Cell Cilium
Plasma Membrane Bounded Cell Projection
Nucleus
Nucleoplasm
Cytoplasm
Golgi Apparatus
Cytosol
Cytoplasmic Stress Granule
Nuclear Speck
Axon
Dendrite
Nucleotide-activated Protein Kinase Complex
Ciliary Basal Body
Neuronal Cell Body
Molecular Function
Protein Binding
Spectrin Binding
Identical Protein Binding
Nucleotide Binding
Chromatin Binding
Protein Kinase Activity
Protein Serine/threonine Kinase Activity
AMP-activated Protein Kinase Activity
Protein Serine/threonine/tyrosine Kinase Activity
Protein Binding
ATP Binding
Kinase Activity
Transferase Activity
Metal Ion Binding
[hydroxymethylglutaryl-CoA Reductase (NADPH)] Kinase Activity
Protein Serine Kinase Activity
Histone H2BS36 Kinase Activity
Biological Process
Sensory Perception Of Sound
Inner Ear Morphogenesis
Photoreceptor Cell Maintenance
Sensory Perception Of Light Stimulus
Equilibrioception
Inner Ear Receptor Cell Differentiation
Inner Ear Receptor Cell Stereocilium Organization
Regulation Of Clathrin-dependent Endocytosis
Cytoplasmic Translation
Chromatin Organization
Chromatin Remodeling
Lipid Metabolic Process
Fatty Acid Metabolic Process
Fatty Acid Biosynthetic Process
Phosphatidylethanolamine Biosynthetic Process
Phosphatidylcholine Biosynthetic Process
Steroid Biosynthetic Process
Cholesterol Biosynthetic Process
Autophagy
Signal Transduction
Steroid Metabolic Process
Cholesterol Metabolic Process
Lipid Biosynthetic Process
Cellular Response To Starvation
Regulation Of Gene Expression
Positive Regulation Of Autophagy
Negative Regulation Of Gene Expression
Response To Muscle Activity
Wnt Signaling Pathway
Sterol Biosynthetic Process
Positive Regulation Of Macroautophagy
Regulation Of Macroautophagy
Cellular Response To Nutrient Levels
Negative Regulation Of TOR Signaling
Cellular Response To Amino Acid Starvation
Cellular Response To Oxidative Stress
TORC1 Signaling
Cellular Response To Glucose Starvation
Glucose Homeostasis
Regulation Of Circadian Rhythm
Negative Regulation Of Apoptotic Process
Positive Regulation Of Glycolytic Process
Negative Regulation Of Translational Initiation
Positive Regulation Of Translational Initiation
Rhythmic Process
Fatty Acid Homeostasis
Protein Localization To Lysosome
Regulation Of Stress Granule Assembly
Regulation Of Microtubule Cytoskeleton Organization
Cellular Response To Calcium Ion
Cellular Response To Glucose Stimulus
Cellular Response To Prostaglandin E Stimulus
Cellular Response To Xenobiotic Stimulus
Protein K6-linked Ubiquitination
Positive Regulation Of Release Of Cytochrome C From Mitochondria
Energy Homeostasis
Hepatocyte Apoptotic Process
Positive Regulation Of Protein Localization
Negative Regulation Of Hepatocyte Apoptotic Process
Negative Regulation Of TORC1 Signaling
Positive Regulation Of TORC1 Signaling
Negative Regulation Of Tubulin Deacetylation
Lipid Droplet Disassembly
Protein Localization To Lipid Droplet
Pathways
Sensory processing of sound by inner hair cells of the cochlea
Sensory processing of sound by outer hair cells of the cochlea
Translocation of SLC2A4 (GLUT4) to the plasma membrane
Macroautophagy
AMPK inhibits chREBP transcriptional activation activity
AMPK inhibits chREBP transcriptional activation activity
Carnitine shuttle
Activation of PPARGC1A (PGC-1alpha) by phosphorylation
Energy dependent regulation of mTOR by LKB1-AMPK
TP53 Regulates Metabolic Genes
Regulation of TP53 Activity through Phosphorylation
Lipophagy
Activation of AMPK downstream of NMDARs
Nuclear events mediated by NFE2L2
AMPK-induced ERAD and lysosome mediated degradation of PD-L1(CD274)
Drugs
Adenosine phosphate
Acetylsalicylic acid
Fostamatinib
Diseases
Usher syndrome (US)
GWAS
Lymphocyte count (
22286170
)
Interacting Genes
19 interacting genes:
AIRIM
ANKRD11
BYSL
CARD9
CBX8
DAXX
DDX6
ENKD1
FAM161B
GEM
HOXB5
INO80B
KIFC3
LMO2
PRKAA2
PRPF31
SCNM1
TCEANC
USH1C
122 interacting genes:
ABI1
ABI2
ACACA
ACACB
AIMP2
AKAP8L
AMOT
AMOTL2
ANAPC11
APPBP2
ARRDC3
AVPI1
C19orf47
CALCOCO1
CALCOCO2
CCDC172
CCDC33
CCNB1IP1
CDC42EP1
CDR2
CDX4
CPSF7
CTAG2
CYSRT1
DNAAF6
DNM2
DNMT1
DVL3
EEF2K
EMILIN1
EPM2A
EPN2
FNDC3B
FOS
GIGYF1
GLI1
GOLGA2
GOLGA6A
GRAP2
HAT1
HMBOX1
HNF4A
HOMEZ
IKZF1
IKZF3
KCTD1
KCTD9
KIAA1328
KIF16B
KIF24
KIFC3
KRT16
KRT31
KRTAP1-3
KRTAP10-3
KRTAP10-9
L3MBTL3
LCN2
LEP
LZTS2
MKRN3
MORN3
MRFAP1
MTUS2
MYCL
MYOZ1
NAB2
NECAB2
NONO
NOTCH2NLA
NRAP
NRBF2
NUTM1
PBXIP1
PFKFB2
PLEKHN1
PRDM6
PRKAB1
PRKAG1
PRKAR1B
PRKN
PRPH
RASAL3
RBBP7
RBPMS
REL
RFX6
RPTOR
SAXO4
SERTAD3
SKIC2
SLA2
SNW1
SOHLH1
SPRY1
STAC2
STK11
TCF4
TFAP2A
TIFA
TLE5
TMOD1
TRIP13
TRIP6
TSC22D4
UBC
UBE2I
USH1C
USH1G
USHBP1
VPS28
VPS37B
VPS52
WASHC1
WWP1
WWP2
YPEL3
ZBTB8A
ZMYND12
ZNF212
ZNF397
ZSCAN23
Entrez ID
124590
5563
HPRD ID
09648
02735
Ensembl ID
ENSG00000182040
ENSG00000162409
Uniprot IDs
B4DL95
Q495M9
P54646
PDB IDs
2L7T
3K1R
3PVL
2H6D
2LTU
2YZA
3AQV
4CFE
4CFF
4ZHX
5EZV
5ISO
6B1U
6B2E
6BX6
7MYJ
8BIK
Enriched GO Terms of Interacting Partners
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Protein Binding
Negative Regulation Of DNA-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Identical Protein Binding
Regulation Of DNA-templated Transcription
Regulation Of RNA Biosynthetic Process
Negative Regulation Of RNA Metabolic Process
Cytosol
Supramolecular Fiber Organization
Cytoplasm
Negative Regulation Of Metabolic Process
Regulation Of RNA Metabolic Process
Regulation Of Primary Metabolic Process
Negative Regulation Of Macromolecule Biosynthetic Process
Negative Regulation Of Nucleobase-containing Compound Metabolic Process
Negative Regulation Of Biosynthetic Process
Regulation Of Nucleobase-containing Compound Metabolic Process
Regulation Of Metabolic Process
Regulation Of Macromolecule Metabolic Process
Regulation Of Transcription By RNA Polymerase II
Malonyl-CoA Biosynthetic Process
Acetyl-CoA Carboxylase Activity
Nucleus
Negative Regulation Of Macromolecule Metabolic Process
Regulation Of Macromolecule Biosynthetic Process
Response To Prolactin
Establishment Of Cell Polarity Involved In Ameboidal Cell Migration
Negative Regulation Of Transcription By RNA Polymerase II
Regulation Of Gene Expression
Cytoskeleton
Cellular Component Assembly
Autophagy
Regulation Of Growth
Transcription Factor Binding
Equilibrioception
Keratin Filament
Microtubule Motor Activity
Cullin Family Protein Binding
Microtubule
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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