CCL27 and ACKR2

Number of citations of the paper that reports this interaction (PMID 11821900)
79

Data Source:
HPRD (in vivo)

		CCL27	ACKR2
Gene Name		chemokine (C-C motif) ligand 27	atypical chemokine receptor 2
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Extracellular Space	Early Endosome Actin Filament Plasma Membrane Integral Component Of Plasma Membrane Recycling Endosome
	Molecular Function	Chemokine Activity	Chemokine Receptor Activity Scavenger Receptor Activity C-C Chemokine Receptor Activity C-X-C Chemokine Receptor Activity C-C Chemokine Binding
	Biological Process	Chemotaxis Immune Response Cell-cell Signaling Cell Chemotaxis	Receptor-mediated Endocytosis Chemotaxis Inflammatory Response Immune Response G-protein Coupled Receptor Signaling Pathway Multicellular Organismal Development Neutrophil Activation Chemokine-mediated Signaling Pathway
Pathways		Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) Signaling by GPCR GPCR downstream signaling Peptide ligand-binding receptors Chemokine receptors bind chemokines Class A/1 (Rhodopsin-like receptors) G alpha (i) signalling events Metabolic disorders of biological oxidation enzymes GPCR ligand binding	Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) Signaling by GPCR Peptide ligand-binding receptors Chemokine receptors bind chemokines Class A/1 (Rhodopsin-like receptors) Metabolic disorders of biological oxidation enzymes GPCR ligand binding
Drugs
Diseases
GWAS
Protein-Protein Interactions		2 interactors: ACKR2 CCR10	16 interactors: APP CCL11 CCL13 CCL14 CCL19 CCL2 CCL21 CCL25 CCL27 CCL28 CCL3 CCL3L3 CCL4 CCL5 CCL7 CCL8
Entrez ID		10850	1238
HPRD ID		05321	09095
Ensembl ID		ENSG00000213927	ENSG00000144648
Uniprot IDs		Q5VZ77 Q9Y4X3	O00590
PDB IDs		2KUM
Enriched GO Terms of Interacting Partners?		Neutrophil Activation Chemokine-mediated Signaling Pathway Receptor-mediated Endocytosis Inflammatory Response Cytokine-mediated Signaling Pathway Leukocyte Activation Cellular Response To Cytokine Stimulus Chemotaxis Endocytosis Cell Activation Response To Cytokine G-protein Coupled Receptor Signaling Pathway Locomotion Immune Response Defense Response Vesicle-mediated Transport Response To External Stimulus Cellular Response To Organic Substance Immune System Process Response To Organic Substance Positive Regulation Of Cytosolic Calcium Ion Concentration Cytosolic Calcium Ion Homeostasis Cell Surface Receptor Signaling Pathway Response To Stress Cellular Calcium Ion Homeostasis Calcium Ion Homeostasis	Cell Chemotaxis Chemotaxis Cell Migration Locomotion Immune Response Cell Motility Cellular Calcium Ion Homeostasis Calcium Ion Homeostasis Movement Of Cell Or Subcellular Component Cellular Metal Ion Homeostasis Inflammatory Response Response To External Stimulus Cellular Cation Homeostasis Cellular Ion Homeostasis Metal Ion Homeostasis Regulation Of Leukocyte Migration Cellular Chemical Homeostasis Immune System Process Ion Homeostasis Cellular Homeostasis Leukocyte Chemotaxis Eosinophil Chemotaxis Leukocyte Migration Chemical Homeostasis Eosinophil Migration Positive Regulation Of Leukocyte Chemotaxis Regulation Of Lymphocyte Migration Defense Response Positive Regulation Of Leukocyte Migration Positive Regulation Of Chemotaxis Positive Regulation Of Natural Killer Cell Chemotaxis Regulation Of Cell Migration Positive Regulation Of Behavior Regulation Of Cell Motility Granulocyte Chemotaxis Regulation Of Chemotaxis Homeostatic Process Regulation Of Locomotion Regulation Of Cellular Component Movement Positive Regulation Of Cell Migration Positive Regulation Of Cell Motility Regulation Of Behavior Positive Regulation Of Cellular Component Movement Positive Regulation Of Locomotion Monocyte Chemotaxis Negative Regulation Of Leukocyte Tethering Or Rolling Negative Regulation Of Leukocyte Migration Cellular Response To Stimulus Response To Stress Regulation Of Granulocyte Chemotaxis
Tagcloud ?		classifier consisting constructed correct costly distinguish easy eczema era goal handle insight investigating misdiagnosed nos2 occasionally omics opposed pathogeneses personalized predicts psoriasis reach reliably signature simultaneously technologies throughput ultimate
Tagcloud (Difference) ?		classifier consisting constructed correct costly distinguish easy eczema era goal handle insight investigating misdiagnosed nos2 occasionally omics opposed pathogeneses personalized predicts psoriasis reach reliably signature simultaneously technologies throughput ultimate
Tagcloud (Intersection) ?