CCL27 and CCR10

Number of citations of the paper that reports this interaction (PMID 11821900)
79

Data Source:
HPRD (in vivo)

		CCL27	CCR10
Gene Name		chemokine (C-C motif) ligand 27	chemokine (C-C motif) receptor 10
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Extracellular Space	Plasma Membrane Integral Component Of Plasma Membrane Cell Surface
	Molecular Function	Chemokine Activity	G-protein Coupled Receptor Activity C-C Chemokine Receptor Activity
	Biological Process	Chemotaxis Immune Response Cell-cell Signaling Cell Chemotaxis	Chemotaxis Immune Response G-protein Coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Chemokine-mediated Signaling Pathway
Pathways		Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) Signaling by GPCR GPCR downstream signaling Peptide ligand-binding receptors Chemokine receptors bind chemokines Class A/1 (Rhodopsin-like receptors) G alpha (i) signalling events Metabolic disorders of biological oxidation enzymes GPCR ligand binding	Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) Signaling by GPCR GPCR downstream signaling Peptide ligand-binding receptors Chemokine receptors bind chemokines Class A/1 (Rhodopsin-like receptors) G alpha (i) signalling events Metabolic disorders of biological oxidation enzymes GPCR ligand binding
Drugs
Diseases
GWAS
Protein-Protein Interactions		2 interactors: ACKR2 CCR10	10 interactors: CCL19 CCL2 CCL21 CCL25 CCL27 CCL28 CCL7 CCR7 CXCL13 PRRC2A
Entrez ID		10850	2826
HPRD ID		05321	02586
Ensembl ID		ENSG00000213927
Uniprot IDs		Q5VZ77 Q9Y4X3	P46092
PDB IDs		2KUM
Enriched GO Terms of Interacting Partners?		Neutrophil Activation Chemokine-mediated Signaling Pathway Receptor-mediated Endocytosis Inflammatory Response Cytokine-mediated Signaling Pathway Leukocyte Activation Cellular Response To Cytokine Stimulus Chemotaxis Endocytosis Cell Activation Response To Cytokine G-protein Coupled Receptor Signaling Pathway Locomotion Immune Response Defense Response Vesicle-mediated Transport Response To External Stimulus Cellular Response To Organic Substance Immune System Process Response To Organic Substance Positive Regulation Of Cytosolic Calcium Ion Concentration Cytosolic Calcium Ion Homeostasis Cell Surface Receptor Signaling Pathway Response To Stress Cellular Calcium Ion Homeostasis Calcium Ion Homeostasis	Cell Chemotaxis Regulation Of Leukocyte Migration Chemotaxis Positive Regulation Of Leukocyte Chemotaxis Cell Migration Positive Regulation Of Leukocyte Migration Cell Motility Leukocyte Migration Leukocyte Chemotaxis Positive Regulation Of Chemotaxis Regulation Of Cell Migration Cellular Calcium Ion Homeostasis Positive Regulation Of Behavior Calcium Ion Homeostasis Regulation Of Cell Motility Regulation Of Chemotaxis Locomotion Regulation Of Locomotion Immune Response Regulation Of Cellular Component Movement Positive Regulation Of Cell Adhesion Cellular Metal Ion Homeostasis Movement Of Cell Or Subcellular Component Regulation Of Behavior Inflammatory Response Cellular Cation Homeostasis Regulation Of Dendritic Cell Dendrite Assembly Cellular Ion Homeostasis Metal Ion Homeostasis Negative Regulation Of Leukocyte Migration Cellular Chemical Homeostasis Response To External Stimulus Negative Regulation Of Leukocyte Tethering Or Rolling Ion Homeostasis Regulation Of Cell Adhesion Regulation Of Lymphocyte Migration Immune System Process Regulation Of Granulocyte Chemotaxis Positive Regulation Of Cell Migration Establishment Of T Cell Polarity Positive Regulation Of Cell Motility Cellular Homeostasis Regulation Of Immune System Process Positive Regulation Of Cellular Component Movement Positive Regulation Of Locomotion Regulation Of Cell-cell Adhesion Positive Regulation Of Cytosolic Calcium Ion Concentration Positive Regulation Of Dendritic Cell Antigen Processing And Presentation Chemical Homeostasis Positive Regulation Of Cell-matrix Adhesion
Tagcloud ?		classifier consisting constructed correct costly distinguish easy eczema era goal handle insight investigating misdiagnosed nos2 occasionally omics opposed pathogeneses personalized predicts psoriasis reach reliably signature simultaneously technologies throughput ultimate	allograft allografts alloreactivity archived arrays augur cd138 cd154 cd19 cd27 existed ig iga igg igll1 immunocyte immunocytes intestine itx mucosal prone protracted reconstitution rejecting rejection repopulation serial stap1 undergoes
Tagcloud (Difference) ?		classifier consisting constructed correct costly distinguish easy eczema era goal handle insight investigating misdiagnosed nos2 occasionally omics opposed pathogeneses personalized predicts psoriasis reach reliably signature simultaneously technologies throughput ultimate	allograft allografts alloreactivity archived arrays augur cd138 cd154 cd19 cd27 existed ig iga igg igll1 immunocyte immunocytes intestine itx mucosal prone protracted reconstitution rejecting rejection repopulation serial stap1 undergoes
Tagcloud (Intersection) ?