PRPF4 and GPKOW

Number of citations of the paper that reports this interaction (PMID 22365833)
24

Data Source:
BioGRID (two hybrid, affinity chromatography technology)

		PRPF4	GPKOW
Gene Name		pre-mRNA processing factor 4	G patch domain and KOW motifs
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex Cajal Body Nuclear Speck U4/U6 X U5 Tri-snRNP Complex U4/U6 SnRNP	Nucleoplasm
	Molecular Function	Protein Binding U6 SnRNA Binding U4 SnRNA Binding	Molecular_function Nucleic Acid Binding Protein Binding
	Biological Process	RNA Splicing, Via Transesterification Reactions MRNA Splicing, Via Spliceosome RNA Processing RNA Splicing Gene Expression	Biological_process
Pathways		Processing of Capped Intron-Containing Pre-mRNA mRNA Splicing mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS
Protein-Protein Interactions		12 interactors: APP ATP5J2 CLK1 GPKOW NHP2L1 PPIH PRPF3 PRPF31 SRSF1 TGFBR1 U2AF1 WBP4	16 interactors: APP BUD13 CCDC57 GOLGA2 NINL PPP1CA PRPF4 PRPF8 ROPN1 SH3GL1 TCEA2 TERF2IP TRAF2 TRIM23 WDR77 WDR83
Entrez ID		9128	27238
HPRD ID		08479	06737
Ensembl ID		ENSG00000136875
Uniprot IDs		O43172 Q5T1M7	Q92917
PDB IDs		1MZW
Enriched GO Terms of Interacting Partners?		MRNA Processing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions MRNA Metabolic Process RNA Processing RNA Splicing MRNA 3'-end Processing Spliceosomal Tri-snRNP Complex Assembly Ribonucleoprotein Complex Biogenesis RNA 3'-end Processing MRNA Cis Splicing, Via Spliceosome RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Gene Expression Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Ribonucleoprotein Complex Assembly Cellular Nitrogen Compound Metabolic Process Spliceosomal SnRNP Assembly Termination Of RNA Polymerase II Transcription Nitrogen Compound Metabolic Process Peptidyl-threonine Phosphorylation MRNA Export From Nucleus DNA-templated Transcription, Termination RNA Export From Nucleus Cellular Metabolic Process Synaptic Growth At Neuromuscular Junction Regulation Of RNA Splicing Collateral Sprouting In Absence Of Injury Cellular Component Assembly Peptidyl-serine Phosphorylation Nuclear Export MRNA Transport RNA Transport Regulation Of Protein Binding Collateral Sprouting Axon Midline Choice Point Recognition MRNA 5'-splice Site Recognition RNA Localization Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Axon Choice Point Recognition Cellular Macromolecular Complex Assembly Parathyroid Gland Development Neuron Remodeling Intracellular Transport Endothelial Cell Activation	MRNA Processing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions MRNA Metabolic Process RNA Processing RNA Splicing Regulation Of Protein Binding RNA Metabolic Process Gene Expression Spliceosomal SnRNP Assembly Regulation Of Binding Negative Regulation Of DNA Recombination At Telomere Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Synaptic Growth At Neuromuscular Junction Nucleobase-containing Compound Metabolic Process Collateral Sprouting In Absence Of Injury Positive Regulation Of NF-kappaB Transcription Factor Activity Secretory Columnal Luminar Epithelial Cell Differentiation Involved In Prostate Glandular Acinus Development Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Collateral Sprouting Axon Midline Choice Point Recognition Protection From Non-homologous End Joining At Telomere Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Peptidase Activity Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Telomere Capping Protein Localization To Chromosome, Telomeric Region Axon Choice Point Recognition Negative Regulation Of Glial Cell Apoptotic Process
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