SFR1 and NDC80

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		SFR1	NDC80
Gene Name		SWI5-dependent recombination repair 1	NDC80 kinetochore complex component
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Swi5-Sfr1 Complex	Chromosome, Centromeric Region Kinetochore Condensed Chromosome Kinetochore Condensed Nuclear Chromosome Outer Kinetochore Nucleus Cytosol Membrane Ndc80 Complex
	Molecular Function	Protein Binding	Structural Constituent Of Cytoskeleton Protein Binding
	Biological Process	Double-strand Break Repair Via Homologous Recombination	Mitotic Sister Chromatid Segregation Establishment Of Mitotic Spindle Orientation Mitotic Cell Cycle Mitotic Spindle Organization Chromosome Segregation Mitotic Nuclear Division Attachment Of Spindle Microtubules To Kinetochore Cell Division Attachment Of Mitotic Spindle Microtubules To Kinetochore
Pathways			Mitotic Prometaphase Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion Mitotic Anaphase Mitotic Metaphase and Anaphase Cell Cycle, Mitotic M Phase
Drugs
Diseases
GWAS
Protein-Protein Interactions		14 interactors: CDC5L CEP70 DTNBP1 EXOC1 HMBOX1 MRFAP1L1 NDC80 NMI RAD51 RINT1 RNF40 SWI5 TFIP11 TRAF3IP1	45 interactors: AMOTL2 ATF4 ATP5O AURKA AURKB BLOC1S6 CALCOCO1 CCDC101 CCDC53 CCHCR1 CCNH CCNK CENPH HAUS1 HGS IFT20 INPP1 KLC3 KLHL12 KRT6B MAD1L1 MAD2L1 MED4 MFAP1 MIS12 NDE1 NDEL1 NEK2 NUF2 PFDN1 PSMC2 RB1 RUFY4 SFR1 SKA1 SMC1A SPC25 STX11 TFIP11 TNIP1 TOM1L1 TP53BP2 TXLNA USHBP1 ZWINT
Entrez ID		119392	10403
HPRD ID		12590	06277
Ensembl ID		ENSG00000156384	ENSG00000080986
Uniprot IDs		Q86XK3	A8K031 O14777
PDB IDs			2IGP 2VE7 3IZ0
Enriched GO Terms of Interacting Partners?		Cellular Response To Ionizing Radiation Cell Cycle Organelle Organization Regulation Of Signal Transduction Involved In Mitotic G2 DNA Damage Checkpoint Spliceosomal Complex Disassembly Double-strand Break Repair Via Homologous Recombination Recombinational Repair Positive Regulation Of DNA Ligation Cellular Response To Camptothecin Cell Cycle Process Response To Camptothecin Regulation Of Response To DNA Damage Stimulus Microtubule-based Transport Cytoskeleton-dependent Intracellular Transport Cellular Response To Radiation Attachment Of Mitotic Spindle Microtubules To Kinetochore DNA Recombinase Assembly Response To Ionizing Radiation Double-strand Break Repair Establishment Of Localization In Cell DNA Repair Regulation Of Dopamine Receptor Signaling Pathway Negative Regulation Of Smoothened Signaling Pathway Involved In Dorsal/ventral Neural Tube Patterning Histone H2B Ubiquitination Platelet Dense Granule Organization See more	Mitotic Nuclear Division Mitotic Cell Cycle Mitotic Cell Cycle Process Cell Division Cell Cycle Chromosome Segregation Cell Cycle Process Negative Regulation Of Cell Cycle Centrosome Separation Organelle Organization Regulation Of Cell Cycle Microtubule-based Process Regulation Of Cell Cycle Process Mitotic Spindle Organization Regulation Of Mitotic Cell Cycle Cellular Localization Mitotic Centrosome Separation Microtubule Cytoskeleton Organization Regulation Of Mitotic Nuclear Division Centrosome Localization Spindle Organization Negative Regulation Of Mitotic Cell Cycle Cell Cycle Checkpoint Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Cell Division Mitotic Sister Chromatid Segregation Regulation Of Chromosome Segregation Mitotic Cell Cycle Checkpoint Sister Chromatid Segregation Centrosome Organization Organelle Localization Establishment Of Localization In Cell Microtubule Organizing Center Organization Centrosome Cycle Microtubule-based Transport Cytoskeleton-dependent Intracellular Transport Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Intracellular Transport Chromosome Organization Negative Regulation Of Cell Division Spindle Assembly Organelle Assembly Spindle Stabilization Cytoskeleton Organization Protein Localization To Chromosome Establishment Of Organelle Localization Regulation Of Organelle Organization Establishment Of Vesicle Localization Protein Localization To Organelle See more
Tagcloud ?		abundance accumulated accumulation arabidopsis ark ark1 ark3 bacterial brassica defence discuss exogenously families infiltration members mrnas neither overlapping possibility potentialization resembled sa salicylic sfr2 sfr3 timing transcripts wounding	assembled ccan cenh3 cenp centromere centromeres centromeric continues deposition egg entails exit immunoprecipitate interphase kinetochore kinetochores mis12 mitosis orchestrate precedes propagation reconstituted segregation sixteen soon spite vertebrate w xenopus
Tagcloud (Difference) ?		abundance accumulated accumulation arabidopsis ark ark1 ark3 bacterial brassica defence discuss exogenously families infiltration members mrnas neither overlapping possibility potentialization resembled sa salicylic sfr2 sfr3 timing transcripts wounding	assembled ccan cenh3 cenp centromere centromeres centromeric continues deposition egg entails exit immunoprecipitate interphase kinetochore kinetochores mis12 mitosis orchestrate precedes propagation reconstituted segregation sixteen soon spite vertebrate w xenopus
Tagcloud (Intersection) ?