SFR1 and DTNBP1

Number of citations of the paper that reports this interaction (PMID 17043677)
96

Data Source:
BioGRID (two hybrid)

		SFR1	DTNBP1
Gene Name		SWI5-dependent recombination repair 1	dystrobrevin binding protein 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Swi5-Sfr1 Complex	Nucleus Cytoplasm Endoplasmic Reticulum Membrane Cytosol Endosome Membrane Postsynaptic Density Sarcoplasm Cell Junction Axon Growth Cone Synaptic Vesicle Membrane BLOC-1 Complex Melanosome Membrane Sarcolemma Neuron Projection Dendritic Spine Postsynaptic Membrane
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Double-strand Break Repair Via Homologous Recombination	Positive Regulation Of Neurotransmitter Secretion Post-Golgi Vesicle-mediated Transport Blood Coagulation Anterograde Axon Cargo Transport Positive Regulation Of Gene Expression Regulation Of Dopamine Secretion Neuron Projection Development Actin Cytoskeleton Reorganization Melanosome Organization Anterograde Synaptic Vesicle Transport Neuron Projection Morphogenesis Platelet Dense Granule Organization Regulation Of Dopamine Receptor Signaling Pathway Membrane Organization
Pathways			Golgi Associated Vesicle Biogenesis trans-Golgi Network Vesicle Budding Clathrin derived vesicle budding
Drugs
Diseases
GWAS
Protein-Protein Interactions		14 interactors: CDC5L CEP70 DTNBP1 EXOC1 HMBOX1 MRFAP1L1 NDC80 NMI RAD51 RINT1 RNF40 SWI5 TFIP11 TRAF3IP1	53 interactors: ABI3 AKAP6 ARFIP2 BLOC1S5 BLOC1S6 BRF1 BRK1 C19orf66 CCDC146 CCDC153 CCDC53 CCHCR1 CCNA2 CCND3 CMYA5 DCTN1 DGCR6L DST DTNA DTNB ELOVL7 EXOC4 EXOC7 GLTSCR1L HAUS1 IFT20 IPO5 KALRN KANSL1 KIAA0408 KIFC3 MACF1 NBEA NDN NUF2 P4HA3 PSME3 RAB11A RBSN SDCBP SFR1 SNAPIN SRGAP3 SSC5D SYBU SYNE1 TRAF3IP1 TRIM2 TRIM27 TRIM32 TRIM9 TXLNB ZNF490
Entrez ID		119392	84062
HPRD ID		12590	06190
Ensembl ID		ENSG00000156384	ENSG00000047579
Uniprot IDs		Q86XK3	D6RJC6 Q96EV8
PDB IDs
Enriched GO Terms of Interacting Partners?		Cellular Response To Ionizing Radiation Cell Cycle Organelle Organization Regulation Of Signal Transduction Involved In Mitotic G2 DNA Damage Checkpoint Spliceosomal Complex Disassembly Double-strand Break Repair Via Homologous Recombination Recombinational Repair Positive Regulation Of DNA Ligation Cellular Response To Camptothecin Cell Cycle Process Response To Camptothecin Regulation Of Response To DNA Damage Stimulus Microtubule-based Transport Cytoskeleton-dependent Intracellular Transport Cellular Response To Radiation Attachment Of Mitotic Spindle Microtubules To Kinetochore DNA Recombinase Assembly Response To Ionizing Radiation Double-strand Break Repair Establishment Of Localization In Cell DNA Repair Regulation Of Dopamine Receptor Signaling Pathway Negative Regulation Of Smoothened Signaling Pathway Involved In Dorsal/ventral Neural Tube Patterning Histone H2B Ubiquitination Platelet Dense Granule Organization	Establishment Of Localization In Cell Movement Of Cell Or Subcellular Component Cellular Pigmentation Cellular Localization Endosomal Transport Microtubule-based Transport Cytoskeleton-dependent Intracellular Transport Organelle Organization Intracellular Transport Melanosome Transport Pigment Granule Transport Establishment Of Melanosome Localization Melanosome Localization Organelle Localization Microtubule-based Process Vesicle-mediated Transport Microtubule-based Movement Establishment Of Vesicle Localization Establishment Of Organelle Localization Pigmentation Vesicle Localization Protein Localization Protein Transport Anterograde Synaptic Vesicle Transport Establishment Of Protein Localization Melanosome Organization Pigment Granule Organization Anterograde Axon Cargo Transport Exocytosis Secretion By Cell Cell Projection Organization Synaptic Vesicle Transport Positive Regulation Of Cell Growth Endosome To Melanosome Transport Pigment Granule Maturation Axon Cargo Transport Small GTPase Mediated Signal Transduction Secretion Synaptic Vesicle Exocytosis Cellular Pigment Accumulation Nervous System Development Regulation Of Calcineurin-NFAT Signaling Cascade Cytoplasmic Transport Transport Positive Regulation Of Pigment Cell Differentiation Mitotic Nuclear Division Neuron Development Positive Regulation Of Developmental Pigmentation Negative Regulation Of Viral Release From Host Cell Generation Of Neurons
Tagcloud ?		abundance accumulated accumulation arabidopsis ark ark1 ark3 bacterial brassica defence discuss exogenously families infiltration members mrnas neither overlapping possibility potentialization resembled sa salicylic sfr2 sfr3 timing transcripts wounding	additive alleles cc convergent correction dysbindin glutamatergic heterozygotes homozygotes india irrespective morphometry neuregulin noted nrg1 pathophysiological polymorphism polymorphisms preliminary reductions rs1011313 rs35753505 schizophrenia tc trend uncorrected viz volumetric voxel
Tagcloud (Difference) ?		abundance accumulated accumulation arabidopsis ark ark1 ark3 bacterial brassica defence discuss exogenously families infiltration members mrnas neither overlapping possibility potentialization resembled sa salicylic sfr2 sfr3 timing transcripts wounding	additive alleles cc convergent correction dysbindin glutamatergic heterozygotes homozygotes india irrespective morphometry neuregulin noted nrg1 pathophysiological polymorphism polymorphisms preliminary reductions rs1011313 rs35753505 schizophrenia tc trend uncorrected viz volumetric voxel
Tagcloud (Intersection) ?