CKM and TRIM55

Number of citations of the paper that reports this interaction (PMID 18157088)
41

Data Source:
BioGRID (two hybrid)

		CKM	TRIM55
Gene Name		creatine kinase, muscle	tripartite motif containing 55
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol	Nucleus Cytoplasm Microtubule
	Molecular Function	Creatine Kinase Activity ATP Binding	Signal Transducer Activity Zinc Ion Binding Identical Protein Binding
	Biological Process	Creatine Metabolic Process Phosphorylation Cellular Nitrogen Compound Metabolic Process Small Molecule Metabolic Process Phosphocreatine Biosynthetic Process	Signal Transduction
Pathways		Metabolism of amino acids and derivatives Creatine metabolism
Drugs		Creatine (Diaminomethyl-Methyl-Amino)-Acetic Acid Adenosine-5\'-Diphosphate D-Arginine
Diseases
GWAS			Response to statin therapy ( 22666496)
Protein-Protein Interactions		10 interactors: ASB9 CBLC CKB FHL2 MYOC MYOM2 TRIM54 TRIM55 TRIM63 YWHAQ	61 interactors: ACTA1 ANKRD1 ATP5B ATXN3 ATXN3L BRAP CKM DCAF6 DES EEF1G EHHADH EIF3E ESPL1 FHL2 FLNA FLNB FLNC GFM1 GMEB1 LMCD1 MDM4 MRPL19 MRPL41 MYBPC1 MYBPC3 MYOT MYOZ1 NDUFA1 NEB NEBL NOMO1 OTUB1 OTUB2 PCGF1 PIAS1 PIAS2 PIAS3 RNF114 SQSTM1 STAM TCAP TNNI1 TNNI2 TNNI3 TRIM27 TRIM54 TRIM63 TTN UBE2D1 UBE2D2 UBE2D3 UCHL3 UCHL5 USP13 USP28 USP4 USP5 USP7 USP8 UXT YOD1
Entrez ID		1158	84675
HPRD ID		00426	05927
Ensembl ID		ENSG00000104879	ENSG00000147573
Uniprot IDs		B2R892 P06732	Q9BYV6
PDB IDs		1I0E
Enriched GO Terms of Interacting Partners?		Skeletal Muscle Adaptation Substantia Nigra Development Muscle System Process Signal Transduction Neural Nucleus Development Signaling Cell Communication ERBB2-ERBB3 Signaling Pathway Skeletal Muscle Hypertrophy Midbrain Development ERBB2 Signaling Pathway Cellular Response To Stimulus Atrial Cardiac Muscle Cell Development Protein Ubiquitination Osteoblast Differentiation Response To Electrical Stimulus Involved In Regulation Of Muscle Adaptation Protein Modification By Small Protein Conjugation Negative Regulation Of Cytoskeleton Organization Non-canonical Wnt Signaling Pathway Via JNK Cascade Skeletal Muscle Atrophy Cellular Chloride Ion Homeostasis Non-canonical Wnt Signaling Pathway Via MAPK Cascade Striated Muscle Atrophy Muscle Atrophy Clustering Of Voltage-gated Sodium Channels Chloride Ion Homeostasis Muscle Contraction Response To Stimulus Creatine Metabolic Process Positive Regulation Of Mitochondrial Depolarization Negative Regulation Of Stress Fiber Assembly Negative Regulation Of Epidermal Growth Factor-activated Receptor Activity Neuronal Ion Channel Clustering Regulation Of Organelle Organization Negative Regulation Of Actin Filament Bundle Assembly Ossification Heart Trabecula Formation	Actin-myosin Filament Sliding Muscle Filament Sliding Actin-mediated Cell Contraction Protein Deubiquitination Protein Modification By Small Protein Removal Actin Filament-based Movement Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Muscle Contraction Actin Filament-based Process Cellular Protein Catabolic Process Protein Catabolic Process Muscle System Process Protein K48-linked Deubiquitination Cellular Macromolecule Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Regulation Of Proteasomal Protein Catabolic Process Regulation Of Protein Catabolic Process Striated Muscle Cell Development Cellular Protein Metabolic Process Muscle Structure Development Muscle Cell Development Protein K63-linked Deubiquitination Myofibril Assembly Proteolysis Cellular Protein Modification Process Striated Muscle Tissue Development Cardiac Muscle Tissue Morphogenesis Striated Muscle Cell Differentiation Muscle Tissue Development Muscle Tissue Morphogenesis Actomyosin Structure Organization Muscle Organ Morphogenesis Cardiac Muscle Tissue Development Protein Metabolic Process Muscle Organ Development Protein Modification By Small Protein Conjugation Muscle Cell Differentiation Myosin Filament Assembly Catabolic Process Actin Cytoskeleton Organization Skeletal Muscle Thin Filament Assembly Cytoskeleton Organization Skeletal Myofibril Assembly Response To Muscle Stretch Heart Morphogenesis Striated Muscle Contraction Cellular Process
Tagcloud ?		auto cd cdai ckms colitis crohn diphthamide gangliosides gm3 ibd ibds immunomodulating immunomodulation implicate kp kynurenine metabolites metabolome metabolomics nineteen picolinic plasmas q qa quinolinic th17 uc ulcerative untargeted
Tagcloud (Difference) ?		auto cd cdai ckms colitis crohn diphthamide gangliosides gm3 ibd ibds immunomodulating immunomodulation implicate kp kynurenine metabolites metabolome metabolomics nineteen picolinic plasmas q qa quinolinic th17 uc ulcerative untargeted
Tagcloud (Intersection) ?