CKM and MYOM2

Number of citations of the paper that reports this interaction (PubMedID 12972258)
0

Data Source:
HPRD (two hybrid)

		CKM	MYOM2
Description		creatine kinase, M-type	myomesin 2
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Space Cytoplasm Cytosol	Cytoplasm Mitochondrion M Band Myosin Filament
	Molecular Function	Nucleotide Binding Catalytic Activity Creatine Kinase Activity Protein Binding ATP Binding Kinase Activity Transferase Activity Transferase Activity, Transferring Phosphorus-containing Groups	Structural Molecule Activity Protein Binding Structural Constituent Of Muscle Kinase Binding
	Biological Process	Phosphocreatine Biosynthetic Process	Extraocular Skeletal Muscle Development Muscle Contraction Sarcomere Organization
Pathways		Creatine metabolism
Drugs		Creatine (Diaminomethyl-Methyl-Amino)-Acetic Acid D-arginine Phosphocreatine
Diseases
GWAS		Alzheimer's disease or family history of Alzheimer's disease ( 30617256) Alzheimer's disease or HDL levels (pleiotropy) ( 30805717) Body mass index ( 26426971) Body mass index (age>50) ( 26426971) Body mass index x age interaction ( 26426971) Body mass index x sex x age interaction (4df test) ( 26426971) Creatine kinase levels in statin users ( 25214527) Intelligence (MTAG) ( 29326435)	Ankylosing spondylitis ( 30946743) Diisocyanate-induced asthma ( 25918132) Heel bone mineral density x serum urate levels interaction ( 34046847) Heschl's gyrus morphology ( 25130324) Metabolite levels ( 23823483) Opioid use cessation ( 31936517) Toenail selenium levels ( 25343990)
Interacting Genes		12 interacting genes: CBLC CKB FHL2 HSPB2 LINC02487 MYOC MYOM2 NOS1AP TRIM54 TRIM55 TRIM63 YWHAQ	14 interacting genes: ANKRD1 CKM DYSF HSPB2 JMJD1C MYBPC2 MYH7 MYH9 NEB RPS6 SEC31A TAF1 TNNT1 TTN
Entrez ID		1158	9172
HPRD ID		00426	04619
Ensembl ID		ENSG00000104879	ENSG00000036448
Uniprot IDs		B2R892 P06732	P54296
PDB IDs		1I0E 7BF2
Enriched GO Terms of Interacting Partners?		Z Disc Skeletal Muscle Adaptation Ubiquitin Protein Ligase Activity M Band Substantia Nigra Development Muscle System Process Skeletal Muscle Hypertrophy Neural Nucleus Development Receptor Tyrosine Kinase Binding Futile Creatine Cycle Atrial Cardiac Muscle Cell Development Response To Electrical Stimulus Involved In Regulation Of Muscle Adaptation Microtubule	Sarcomere Organization Actomyosin Structure Organization Actin Filament-based Process Myosin Filament Somatic Muscle Development Actin-mediated Cell Contraction Skeletal Muscle Contraction Actin Cytoskeleton Organization Structural Constituent Of Muscle Myofibril Transition Between Fast And Slow Fiber Cardiac Muscle Tissue Morphogenesis Actin Filament-based Movement Actin Filament Binding Muscle Tissue Morphogenesis Supramolecular Fiber Regulation Of Skeletal Muscle Adaptation Striated Muscle Contraction Muscle Filament Sliding Actin-myosin Filament Sliding Actin Binding M Band Cardiac Muscle Hypertrophy Z Disc Myosin II Complex Response To Muscle Stretch I Band Muscle Hypertrophy Microfilament Motor Activity Calmodulin Binding Muscle Contraction Cardiac Muscle Contraction Cytoskeleton Organization Myosin Complex Cytoskeletal Motor Activity Cortical Granule Exocytosis Positive Regulation Of Androgen Receptor Signaling Pathway Slow-twitch Skeletal Muscle Fiber Contraction Monocyte Activation Involved In Immune Response Sarcomere Muscle System Process Regulation Of The Force Of Skeletal Muscle Contraction Regulation Of Slow-twitch Skeletal Muscle Fiber Contraction Uropod Organization Actin Cytoskeleton Negative Regulation Of Actin Filament Severing Positive Regulation Of Protein Processing In Phagocytic Vesicle Negative Regulation Of Protein Autoubiquitination P53 Binding Titin-telethonin Complex
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