CKM and LINC02487

Number of citations of the paper that reports this interaction (PubMedID 33194625)
56

Data Source:
BioGRID (unspecified method)

		CKM	LINC02487
Description		creatine kinase, M-type	long intergenic non-protein coding RNA 2487
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Space Cytoplasm Cytosol
	Molecular Function	Nucleotide Binding Catalytic Activity Creatine Kinase Activity Protein Binding ATP Binding Kinase Activity Transferase Activity Transferase Activity, Transferring Phosphorus-containing Groups
	Biological Process	Phosphocreatine Biosynthetic Process
Pathways		Creatine metabolism
Drugs		Creatine (Diaminomethyl-Methyl-Amino)-Acetic Acid D-arginine Phosphocreatine
Diseases
GWAS		Alzheimer's disease or family history of Alzheimer's disease ( 30617256) Alzheimer's disease or HDL levels (pleiotropy) ( 30805717) Body mass index ( 26426971) Body mass index (age>50) ( 26426971) Body mass index x age interaction ( 26426971) Body mass index x sex x age interaction (4df test) ( 26426971) Creatine kinase levels in statin users ( 25214527) Intelligence (MTAG) ( 29326435)
Interacting Genes		12 interacting genes: CBLC CKB FHL2 HSPB2 LINC02487 MYOC MYOM2 NOS1AP TRIM54 TRIM55 TRIM63 YWHAQ	2 interacting genes: CKM USP17L2
Entrez ID		1158	441178
HPRD ID		00426	18827
Ensembl ID		ENSG00000104879	ENSG00000203688
Uniprot IDs		B2R892 P06732
PDB IDs		1I0E 7BF2
Enriched GO Terms of Interacting Partners?		Z Disc Skeletal Muscle Adaptation Ubiquitin Protein Ligase Activity M Band Substantia Nigra Development Muscle System Process Skeletal Muscle Hypertrophy Neural Nucleus Development Receptor Tyrosine Kinase Binding Futile Creatine Cycle Atrial Cardiac Muscle Cell Development Response To Electrical Stimulus Involved In Regulation Of Muscle Adaptation Microtubule	Phosphocreatine Biosynthetic Process Creatine Kinase Activity Regulation Of G2/MI Transition Of Meiotic Cell Cycle CAAX-box Protein Processing Positive Regulation Of MDA-5 Signaling Pathway Negative Regulation Of Protein Targeting To Membrane Positive Regulation Of RIG-I Signaling Pathway Transferase Activity, Transferring Phosphorus-containing Groups Negative Regulation Of GTPase Activity Regulation Of RIG-I Signaling Pathway Protein K63-linked Deubiquitination Protein K48-linked Deubiquitination Negative Regulation Of Protein Processing Negative Regulation Of Protein Maturation Regulation Of Ruffle Assembly Regulation Of Protein Targeting To Membrane Negative Regulation Of Hydrolase Activity Regulation Of Defense Response To Virus By Host Positive Regulation Of Pattern Recognition Receptor Signaling Pathway Regulation Of Protein Processing Regulation Of Protein Maturation Regulation Of Defense Response To Virus
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