EVI5L and NUDT18

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid, two hybrid)
HPRD (two hybrid)

		EVI5L	NUDT18
Gene Name		ecotropic viral integration site 5-like	nudix (nucleoside diphosphate linked moiety X)-type motif 18
Image		No pdb structure
Gene Ontology Annotations	Cellular Component		Cytosol
	Molecular Function	Rab GTPase Activator Activity Protein Binding Rab GTPase Binding	Magnesium Ion Binding Protein Binding 8-oxo-dGDP Phosphatase Activity 8-oxo-GDP Phosphatase Activity 8-hydroxy-dADP Phosphatase Activity
	Biological Process	Positive Regulation Of Rab GTPase Activity Negative Regulation Of Cilium Assembly	Nucleobase-containing Small Molecule Catabolic Process Small Molecule Metabolic Process DADP Catabolic Process DGDP Catabolic Process GDP Catabolic Process Nucleobase-containing Small Molecule Metabolic Process
Pathways
Drugs
Diseases
GWAS		HIV-1 control ( 20205591)
Protein-Protein Interactions		5 interactors: A2M NUDT18 PSEN2 RAB10 SRPK2	34 interactors: APIP COIL CUTC DCTD DHPS DUT EVI5L GLUL GNMT GSE1 HSD17B14 KCTD13 KCTD17 KHDRBS3 KRT15 KRTAP4-12 KXD1 NADK NAT9 NT5C2 PAICS PCBD1 PSME3 RAB3IL1 RABAC1 RAD54B RWDD1 SDPR TARBP2 TERF2IP TIFA TRAF2 TRIM37 ZBED1
Entrez ID		115704	79873
HPRD ID		10044	07992
Ensembl ID		ENSG00000142459
Uniprot IDs		Q96CN4	Q6ZVK8
PDB IDs			3GG6
Enriched GO Terms of Interacting Partners?		Intracellular Signal Transduction GDP Catabolic Process Nuclear Speck Organization DGDP Catabolic Process DADP Catabolic Process Basolateral Protein Localization Negative Regulation Of Complement Activation, Lectin Pathway Establishment Of Protein Localization To Endoplasmic Reticulum Membrane Establishment Of Neuroblast Polarity Purine Ribonucleoside Diphosphate Catabolic Process Nucleobase-containing Small Molecule Catabolic Process Cell Fate Commitment Ribonucleoside Diphosphate Catabolic Process Endoplasmic Reticulum Tubular Network Organization Polarized Epithelial Cell Differentiation Nucleoside Diphosphate Catabolic Process Cell Differentiation Exocytosis Deoxyribonucleoside Diphosphate Metabolic Process Amyloid Precursor Protein Catabolic Process Purine Ribonucleoside Catabolic Process Blood Coagulation, Intrinsic Pathway Negative Regulation Of Complement Activation Membrane Protein Intracellular Domain Proteolysis Deoxyribose Phosphate Catabolic Process Membrane Protein Ectodomain Proteolysis Beta-amyloid Metabolic Process Amyloid Precursor Protein Metabolic Process Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Secretion By Cell Positive Regulation Of Viral Genome Replication Notch Receptor Processing Axonogenesis Golgi To Plasma Membrane Protein Transport Purine Ribonucleotide Catabolic Process Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Morphogenesis Of A Polarized Epithelium Axon Development Regulation Of Epidermal Growth Factor-activated Receptor Activity Asymmetric Protein Localization Cell Morphogenesis Involved In Neuron Differentiation Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Somatic Stem Cell Division Deoxyribonucleotide Catabolic Process Positive Regulation Of Cell Death Small GTPase Mediated Signal Transduction Immune System Process Endoplasmic Reticulum Calcium Ion Homeostasis Secretion	Protein Homooligomerization Protein Oligomerization Nucleoside Metabolic Process Protein Tetramerization Nucleobase-containing Small Molecule Metabolic Process Protein Complex Assembly Cellular Nitrogen Compound Metabolic Process Cellular Component Assembly Protein Homotetramerization Nitrogen Compound Metabolic Process Catabolic Process Small Molecule Metabolic Process S-adenosylmethionine Metabolic Process Purine Nucleoside Metabolic Process Methionine Metabolic Process Regulation Of Protein Homodimerization Activity IMP Metabolic Process Alpha-amino Acid Metabolic Process Nucleotide Biosynthetic Process Positive Regulation Of NF-kappaB Transcription Factor Activity Nucleotide Metabolic Process Polyamine Metabolic Process Cofactor Metabolic Process Nucleobase-containing Compound Metabolic Process Pyrimidine Nucleobase Metabolic Process Protein Autoubiquitination Purine Nucleobase Metabolic Process Sulfur Amino Acid Metabolic Process DUMP Biosynthetic Process Deoxyhypusine Biosynthetic Process From Spermidine DUTP Catabolic Process Negative Regulation Of DNA Recombination At Telomere Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Pyrimidine Nucleoside Biosynthetic Process Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Cellular Amino Acid Metabolic Process I-kappaB Kinase/NF-kappaB Signaling Glutamine Biosynthetic Process MiRNA Loading Onto RISC Involved In Gene Silencing By MiRNA Spermidine Catabolic Process L-methionine Biosynthetic Process From S-adenosylmethionine Cellular Modified Amino Acid Metabolic Process Pyrimidine Nucleotide Metabolic Process Pyrimidine Nucleoside Metabolic Process Targeting Of MRNA For Destruction Involved In RNA Interference DUMP Metabolic Process NADP Biosynthetic Process DUTP Metabolic Process Negative Regulation Of Cilium Assembly
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