EVI5L and NUDT18

Number of citations of the paper that reports this interaction (PubMedID 19060904)
32

Data Source:
BioGRID (two hybrid, two hybrid)
HPRD (two hybrid)

		EVI5L	NUDT18
Description		ecotropic viral integration site 5 like	nudix hydrolase 18
Image		No pdb structure
GO Annotations	Cellular Component		Cytosol
	Molecular Function	GTPase Activator Activity Protein Binding Small GTPase Binding	Protein Binding Hydrolase Activity Nucleoside Diphosphate Phosphatase Activity 8-oxo-dGDP Phosphatase Activity 8-oxo-GDP Phosphatase Activity 8-hydroxy-dADP Phosphatase Activity Metal Ion Binding
	Biological Process	Positive Regulation Of GTPase Activity Negative Regulation Of Cilium Assembly	Nucleotide Metabolic Process DADP Catabolic Process DGDP Catabolic Process GDP Catabolic Process Nucleobase-containing Small Molecule Metabolic Process
Pathways
Drugs
Diseases
GWAS		Alanine aminotransferase levels ( 33547301) HIV-1 viral setpoint ( 20205591) Menarche (age at onset) ( 25231870)
Interacting Genes		15 interacting genes: A2M ANKRD36 AP1M1 CCDC185 DRC4 KRT79 LNX1 NUDT18 PRPF18 PSEN2 RAB10 RBM7 SRPK2 TBC1D21 ZNF648	34 interacting genes: APIP CAVIN2 COIL CUTC DCTD DHPS DUT EVI5L GLUL GNMT GSE1 HSD17B14 KCTD13 KCTD17 KHDRBS3 KRT15 KRTAP4-12 KXD1 NADK NAT9 NT5C2 PAICS PCBD1 PSME3 RAB3IL1 RABAC1 RAD54B RWDD1 TARBP2 TERF2IP TIFA TRAF2 TRIM37 ZBED1
Entrez ID		115704	79873
HPRD ID		10044	07992
Ensembl ID		ENSG00000142459	ENSG00000275074
Uniprot IDs		A0A384MR55 Q96CN4	Q6ZVK8
PDB IDs			3GG6 4HVY
Enriched GO Terms of Interacting Partners?		Flagellated Sperm Motility Cilium Movement Involved In Cell Motility Sperm Motility Cilium-dependent Cell Motility Epithelial Cilium Movement Involved In Extracellular Fluid Movement Cilium Movement Extracellular Transport 14-3-3 Protein Binding U2-type Post-spliceosomal Complex 8-hydroxy-dADP Phosphatase Activity 8-oxo-GDP Phosphatase Activity DGDP Catabolic Process DADP Catabolic Process Axoneme Assembly Negative Regulation Of Complement Activation, Lectin Pathway Generation Of Catalytic Spliceosome For Second Transesterification Step GDP Catabolic Process Interleukin-8 Binding Microtubule Bundle Formation Protein Localization To Basolateral Plasma Membrane Establishment Of Neuroblast Polarity Establishment Of Protein Localization To Endoplasmic Reticulum Membrane 8-oxo-dGDP Phosphatase Activity Outer Dynein Arm Docking Complex	Identical Protein Binding DUMP Biosynthetic Process DTMP Biosynthetic Process Pyrimidine Deoxyribonucleoside Monophosphate Biosynthetic Process Nucleoside Monophosphate Metabolic Process Negative Regulation Of Defense Response To Virus By Host Protein Complex Oligomerization Protein Homooligomerization Pyrimidine Deoxyribonucleotide Biosynthetic Process Nucleoside Monophosphate Biosynthetic Process Deoxyribonucleotide Metabolic Process Cytosol Nucleoside Metabolic Process Deoxyribonucleoside Monophosphate Biosynthetic Process Protein Binding Amino Acid Biosynthetic Process L-amino Acid Metabolic Process Small Molecule Metabolic Process Deoxyribonucleotide Biosynthetic Process 2'-deoxyribonucleotide Biosynthetic Process Methionine Metabolic Process Negative Regulation Of Defense Response To Virus Alpha-amino Acid Metabolic Process Protein-containing Complex Assembly IMP Metabolic Process Nucleotide Biosynthetic Process Purine Nucleobase Metabolic Process Protein Tetramerization Nucleobase-containing Small Molecule Metabolic Process Nucleotide Metabolic Process Purine Nucleoside Metabolic Process Pyrimidine Nucleotide Biosynthetic Process Deoxyhypusine Synthase Activity Deoxyribose Phosphate Catabolic Process Deoxyribonucleotide Catabolic Process DUTP Catabolic Process DUTP Diphosphatase Activity Amino Acid Metabolic Process Intracellular Ammonium Homeostasis Tumor Necrosis Factor Receptor Binding Regulation Of SiRNA Processing Protein-containing Complex Organization TORC2 Complex Disassembly Protein Autosumoylation Phosphoribosylaminoimidazolesuccinocarboxamide Synthase Activity GMP Metabolic Process Phosphoribosylaminoimidazole Carboxylase Activity Nucleoside Phosphotransferase Activity GMP Catabolic Process To Guanine Tubulin N-terminal-methionine Acetyltransferase Activity
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