EVI5L and KRT79

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		EVI5L	KRT79
Description		ecotropic viral integration site 5 like	keratin 79
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Cytosol Intermediate Filament Keratin Filament Extracellular Exosome
	Molecular Function	GTPase Activator Activity Protein Binding Small GTPase Binding	Protein Binding Enzyme Binding Structural Constituent Of Skin Epidermis
	Biological Process	Positive Regulation Of GTPase Activity Negative Regulation Of Cilium Assembly	Keratinization Intermediate Filament Organization
Pathways			Keratinization Formation of the cornified envelope
Drugs
Diseases
GWAS		Alanine aminotransferase levels ( 33547301) HIV-1 viral setpoint ( 20205591) Menarche (age at onset) ( 25231870)
Interacting Genes		15 interacting genes: A2M ANKRD36 AP1M1 CCDC185 DRC4 KRT79 LNX1 NUDT18 PRPF18 PSEN2 RAB10 RBM7 SRPK2 TBC1D21 ZNF648	22 interacting genes: EVI5L KRT13 KRT14 KRT15 KRT16 KRT19 KRT24 KRT25 KRT26 KRT27 KRT28 KRT31 KRT33B KRT34 KRT35 KRT36 KRT37 KRT38 KRT40 SYCE3 TRIM54 USHBP1
Entrez ID		115704	338785
HPRD ID		10044	11183
Ensembl ID		ENSG00000142459	ENSG00000185640
Uniprot IDs		A0A384MR55 Q96CN4	Q5XKE5
PDB IDs
Enriched GO Terms of Interacting Partners?		Flagellated Sperm Motility Cilium Movement Involved In Cell Motility Sperm Motility Cilium-dependent Cell Motility Epithelial Cilium Movement Involved In Extracellular Fluid Movement Cilium Movement Extracellular Transport 14-3-3 Protein Binding U2-type Post-spliceosomal Complex 8-hydroxy-dADP Phosphatase Activity 8-oxo-GDP Phosphatase Activity DGDP Catabolic Process DADP Catabolic Process Axoneme Assembly Negative Regulation Of Complement Activation, Lectin Pathway Generation Of Catalytic Spliceosome For Second Transesterification Step GDP Catabolic Process Interleukin-8 Binding Microtubule Bundle Formation Protein Localization To Basolateral Plasma Membrane Establishment Of Neuroblast Polarity Establishment Of Protein Localization To Endoplasmic Reticulum Membrane 8-oxo-dGDP Phosphatase Activity Outer Dynein Arm Docking Complex	Structural Constituent Of Skin Epidermis Intermediate Filament Organization Intermediate Filament Cytoskeleton Organization Keratin Filament Intermediate Filament-based Process Intermediate Filament Structural Molecule Activity Morphogenesis Of An Epithelium Epithelial Cell Differentiation Tissue Morphogenesis Supramolecular Fiber Organization Cytoskeleton Organization Cytoskeleton Anatomical Structure Morphogenesis Cell Differentiation Cellular Developmental Process Organelle Organization Extracellular Exosome Hair Cycle Developmental Process Structural Constituent Of Cytoskeleton Epidermis Development Cytosol Hair Follicle Morphogenesis Hair Cycle Process Intermediate Filament Cytoskeleton Tissue Development Cornified Envelope Keratinocyte Differentiation Terminal Web Protein Binding Cell Periphery Epidermal Cell Differentiation Keratin Filament Binding Keratinocyte Migration
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