EVI5L and RAB10

Number of citations of the paper that reports this interaction (PubMedID 16923123)
0

Data Source:
BioGRID (two hybrid)

		EVI5L	RAB10
Description		ecotropic viral integration site 5 like	RAB10, member RAS oncogene family
Image		No pdb structure
GO Annotations	Cellular Component		Golgi Membrane Exocyst Cytoplasm Lysosome Endosome Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Trans-Golgi Network Cytosol Cytoskeleton Plasma Membrane Adherens Junction Focal Adhesion Cilium Endosome Membrane Membrane Cytoplasmic Vesicle Membrane Secretory Granule Membrane Phagocytic Vesicle Membrane Cytoplasmic Vesicle Insulin-responsive Compartment Cell Projection Perinuclear Region Of Cytoplasm Recycling Endosome Recycling Endosome Membrane Extracellular Exosome Exocytic Vesicle Endoplasmic Reticulum Tubular Network Secretory Vesicle
	Molecular Function	GTPase Activator Activity Protein Binding Small GTPase Binding	Nucleotide Binding GTPase Activity G Protein Activity Protein Binding GTP Binding Hydrolase Activity GDP Binding Myosin V Binding Cadherin Binding Involved In Cell-cell Adhesion
	Biological Process	Positive Regulation Of GTPase Activity Negative Regulation Of Cilium Assembly	Exocytosis Golgi To Plasma Membrane Transport Axonogenesis Protein Transport Vesicle-mediated Transport Endosomal Transport Antigen Processing And Presentation Polarized Epithelial Cell Differentiation Cellular Response To Insulin Stimulus Golgi To Plasma Membrane Protein Transport Regulated Exocytosis Establishment Of Neuroblast Polarity Endoplasmic Reticulum Tubular Network Organization Protein Localization To Plasma Membrane Establishment Of Protein Localization To Membrane Establishment Of Protein Localization To Endoplasmic Reticulum Membrane Cell-cell Adhesion Protein Localization To Basolateral Plasma Membrane
Pathways			Translocation of SLC2A4 (GLUT4) to the plasma membrane Neutrophil degranulation RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases
GWAS		Alanine aminotransferase levels ( 33547301) HIV-1 viral setpoint ( 20205591) Menarche (age at onset) ( 25231870)	Apolipoprotein B levels ( 32203549) Glycated hemoglobin levels ( 34059833) Immune response to smallpox vaccine (IL-6) ( 22542470) Mean corpuscular hemoglobin ( 27863252 32888494) Mean corpuscular hemoglobin concentration ( 32888494) Mean corpuscular volume ( 27863252 32888494) Metabolite levels (HVA) ( 23319000) Metabolite levels (HVA-5-HIAA Factor score) ( 23319000) Metabolite levels (HVA/MHPG ratio) ( 23319000) Platelet distribution width ( 32888494)
Interacting Genes		15 interacting genes: A2M ANKRD36 AP1M1 CCDC185 DRC4 KRT79 LNX1 NUDT18 PRPF18 PSEN2 RAB10 RBM7 SRPK2 TBC1D21 ZNF648	10 interacting genes: APP CEBPA ENOPH1 EVI5L MICAL1 MTNR1A PPBP RABIF RIMS1 SEPTIN9
Entrez ID		115704	10890
HPRD ID		10044	06692
Ensembl ID		ENSG00000142459	ENSG00000084733
Uniprot IDs		A0A384MR55 Q96CN4	P61026
PDB IDs			5LPN 5SZJ
Enriched GO Terms of Interacting Partners?		Flagellated Sperm Motility Cilium Movement Involved In Cell Motility Sperm Motility Cilium-dependent Cell Motility Epithelial Cilium Movement Involved In Extracellular Fluid Movement Cilium Movement Extracellular Transport 14-3-3 Protein Binding U2-type Post-spliceosomal Complex 8-hydroxy-dADP Phosphatase Activity 8-oxo-GDP Phosphatase Activity DGDP Catabolic Process DADP Catabolic Process Axoneme Assembly Negative Regulation Of Complement Activation, Lectin Pathway Generation Of Catalytic Spliceosome For Second Transesterification Step GDP Catabolic Process Interleukin-8 Binding Microtubule Bundle Formation Protein Localization To Basolateral Plasma Membrane Establishment Of Neuroblast Polarity Establishment Of Protein Localization To Endoplasmic Reticulum Membrane 8-oxo-dGDP Phosphatase Activity Outer Dynein Arm Docking Complex
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