EVI5L and RAB10

Number of citations of the paper that reports this interaction (PMID 16923123)
31

Data Source:
BioGRID (two hybrid)

		EVI5L	RAB10
Gene Name		ecotropic viral integration site 5-like	RAB10, member RAS oncogene family
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component		Exocyst Endosome Endoplasmic Reticulum Membrane Golgi Apparatus Trans-Golgi Network Plasma Membrane Focal Adhesion Endosome Membrane Cytoplasmic Vesicle Membrane Phagocytic Vesicle Membrane Insulin-responsive Compartment Recycling Endosome Recycling Endosome Membrane Extracellular Vesicular Exosome Endoplasmic Reticulum Tubular Network Primary Cilium
	Molecular Function	Rab GTPase Activator Activity Protein Binding Rab GTPase Binding	GTPase Activity GTP Binding GDP Binding Myosin V Binding
	Biological Process	Positive Regulation Of Rab GTPase Activity Negative Regulation Of Cilium Assembly	Intracellular Protein Transport Golgi To Plasma Membrane Transport Vesicle Docking Involved In Exocytosis Axonogenesis Protein Secretion Vesicle-mediated Transport Endosomal Transport Regulation Of Exocytosis Antigen Processing And Presentation Polarized Epithelial Cell Differentiation Rab Protein Signal Transduction Cellular Response To Insulin Stimulus Golgi To Plasma Membrane Protein Transport Establishment Of Neuroblast Polarity Membrane Organization Basolateral Protein Localization Endoplasmic Reticulum Tubular Network Organization Protein Localization To Plasma Membrane Establishment Of Protein Localization To Membrane Establishment Of Protein Localization To Endoplasmic Reticulum Membrane
Pathways			Translocation of GLUT4 to the plasma membrane
Drugs
Diseases
GWAS		HIV-1 control ( 20205591)	Immune response to smallpox vaccine (IL-6) ( 22542470) Metabolite levels (HVA) ( 23319000) Metabolite levels (HVA-5-HIAA Factor score) ( 23319000) Metabolite levels (HVA/MHPG ratio) ( 23319000)
Protein-Protein Interactions		5 interactors: A2M NUDT18 PSEN2 RAB10 SRPK2	9 interactors: APP ENOPH1 EVI5L MICAL1 MTNR1A OPTN PPBP RIMS1 SEPT9
Entrez ID		115704	10890
HPRD ID		10044	06692
Ensembl ID		ENSG00000142459	ENSG00000084733
Uniprot IDs		Q96CN4	P61026
PDB IDs
Enriched GO Terms of Interacting Partners?		Intracellular Signal Transduction GDP Catabolic Process Nuclear Speck Organization DGDP Catabolic Process DADP Catabolic Process Basolateral Protein Localization Negative Regulation Of Complement Activation, Lectin Pathway Establishment Of Protein Localization To Endoplasmic Reticulum Membrane Establishment Of Neuroblast Polarity Purine Ribonucleoside Diphosphate Catabolic Process Nucleobase-containing Small Molecule Catabolic Process Cell Fate Commitment Ribonucleoside Diphosphate Catabolic Process Endoplasmic Reticulum Tubular Network Organization Polarized Epithelial Cell Differentiation Nucleoside Diphosphate Catabolic Process Cell Differentiation Exocytosis Deoxyribonucleoside Diphosphate Metabolic Process Amyloid Precursor Protein Catabolic Process Purine Ribonucleoside Catabolic Process Blood Coagulation, Intrinsic Pathway Negative Regulation Of Complement Activation Membrane Protein Intracellular Domain Proteolysis Deoxyribose Phosphate Catabolic Process Membrane Protein Ectodomain Proteolysis Beta-amyloid Metabolic Process Amyloid Precursor Protein Metabolic Process Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Secretion By Cell Positive Regulation Of Viral Genome Replication Notch Receptor Processing Axonogenesis Golgi To Plasma Membrane Protein Transport Purine Ribonucleotide Catabolic Process Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Morphogenesis Of A Polarized Epithelium Axon Development Regulation Of Epidermal Growth Factor-activated Receptor Activity Asymmetric Protein Localization Cell Morphogenesis Involved In Neuron Differentiation Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Somatic Stem Cell Division Deoxyribonucleotide Catabolic Process Positive Regulation Of Cell Death Small GTPase Mediated Signal Transduction Immune System Process Endoplasmic Reticulum Calcium Ion Homeostasis Secretion	Mating Behavior Mating Exocytosis Platelet Degranulation Secretion By Cell Synaptic Growth At Neuromuscular Junction Collateral Sprouting In Absence Of Injury Negative Regulation Of Cilium Assembly Vesicle-mediated Transport Secretion Negative Regulation Of Receptor Recycling Collateral Sprouting Axon Midline Choice Point Recognition Positive Regulation Of Inhibitory Postsynaptic Membrane Potential Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Defense Response To Bacterium Platelet Activation Axon Choice Point Recognition Golgi Ribbon Formation Sulfur Oxidation
Tagcloud ?			a8 a9 aldehyde aldh3a1 beta4 biglycan chymase cma1 conjunctiva conjunctival fibrovascular gelsolin genechip immunofluorescent infiltrates itraq member1 pterygium s100 s100a8 s100a9 sawdust serpin serpina1 stringent thymosin uninvolved vim wing
Tagcloud (Difference) ?			a8 a9 aldehyde aldh3a1 beta4 biglycan chymase cma1 conjunctiva conjunctival fibrovascular gelsolin genechip immunofluorescent infiltrates itraq member1 pterygium s100 s100a8 s100a9 sawdust serpin serpina1 stringent thymosin uninvolved vim wing
Tagcloud (Intersection) ?