EVI5L and RBM7

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		EVI5L	RBM7
Description		ecotropic viral integration site 5 like	RNA binding motif protein 7
Image		No pdb structure
GO Annotations	Cellular Component		Nucleus Nucleoplasm Nucleolus
	Molecular Function	GTPase Activator Activity Protein Binding Small GTPase Binding	Nucleic Acid Binding RNA Binding Single-stranded RNA Binding Protein Binding SnRNA Binding 14-3-3 Protein Binding Pre-mRNA Intronic Binding
	Biological Process	Positive Regulation Of GTPase Activity Negative Regulation Of Cilium Assembly	Regulation Of Alternative MRNA Splicing, Via Spliceosome SnRNA Catabolic Process Meiotic Cell Cycle
Pathways			mRNA Splicing - Major Pathway Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex Nuclear RNA decay
Drugs
Diseases
GWAS		Alanine aminotransferase levels ( 33547301) HIV-1 viral setpoint ( 20205591) Menarche (age at onset) ( 25231870)	Inflammatory bowel disease ( 28067908) Ulcerative colitis ( 28067908)
Interacting Genes		15 interacting genes: A2M ANKRD36 AP1M1 CCDC185 DRC4 KRT79 LNX1 NUDT18 PRPF18 PSEN2 RAB10 RBM7 SRPK2 TBC1D21 ZNF648	27 interacting genes: APOBEC3C BAG4 CCDC85B CCDC88B CHERP CPSF7 DDX17 DHX8 DMRTB1 EVI5L EXOSC7 EXOSC8 HMG20A HNRNPK KHDRBS1 KHDRBS3 KRT31 QKI RBM10 RBM4 RBMX RBPMS SF1 SF3B2 SNRPA SRSF3 TFIP11
Entrez ID		115704	10179
HPRD ID		10044	11488
Ensembl ID		ENSG00000142459	ENSG00000076053
Uniprot IDs		A0A384MR55 Q96CN4	G3V1T9 J3KPD3 Q9Y580
PDB IDs			2M8H 5IQQ 5LXR 5LXY 7S7B 7S7C
Enriched GO Terms of Interacting Partners?		Flagellated Sperm Motility Cilium Movement Involved In Cell Motility Sperm Motility Cilium-dependent Cell Motility Epithelial Cilium Movement Involved In Extracellular Fluid Movement Cilium Movement Extracellular Transport 14-3-3 Protein Binding U2-type Post-spliceosomal Complex 8-hydroxy-dADP Phosphatase Activity 8-oxo-GDP Phosphatase Activity DGDP Catabolic Process DADP Catabolic Process Axoneme Assembly Negative Regulation Of Complement Activation, Lectin Pathway Generation Of Catalytic Spliceosome For Second Transesterification Step GDP Catabolic Process Interleukin-8 Binding Microtubule Bundle Formation Protein Localization To Basolateral Plasma Membrane Establishment Of Neuroblast Polarity Establishment Of Protein Localization To Endoplasmic Reticulum Membrane 8-oxo-dGDP Phosphatase Activity Outer Dynein Arm Docking Complex	RNA Processing MRNA Metabolic Process MRNA Processing Nucleic Acid Binding RNA Binding Regulation Of MRNA Splicing, Via Spliceosome Regulation Of MRNA Processing MRNA Binding RNA Metabolic Process RNA Splicing Regulation Of RNA Splicing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Regulation Of MRNA Metabolic Process Regulation Of Alternative MRNA Splicing, Via Spliceosome Nucleic Acid Metabolic Process Nucleobase-containing Compound Metabolic Process Spliceosomal Complex Catalytic Step 2 Spliceosome Nucleoplasm Negative Regulation Of MRNA Metabolic Process Nucleus Negative Regulation Of Macromolecule Metabolic Process Pre-mRNA Binding Negative Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of Metabolic Process U5 SnRNA 3'-end Processing U1 SnRNA 3'-end Processing Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of RNA Splicing Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Cytoplasmic Stress Granule Regulation Of RNA Metabolic Process Regulation Of Macromolecule Metabolic Process Negative Regulation Of Biosynthetic Process MiRNA Binding Exoribonuclease Complex Negative Regulation Of RNA Metabolic Process Identical Protein Binding Regulation Of Gene Expression Negative Regulation Of Gene Expression Exonucleolytic Trimming To Generate Mature 3'-end Of 5.8S RRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) TRAMP-dependent TRNA Surveillance Pathway TRNA Surveillance Nuclear Polyadenylation-dependent RRNA Catabolic Process Nuclear Speck Regulation Of Macromolecule Biosynthetic Process U4 SnRNA 3'-end Processing Macromolecule Metabolic Process
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