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ZFYVE26

Description zinc finger FYVE-type containing 26
Image No pdb structure
GO Annotations Cellular Component
  • Cytoplasm
  • Lysosome
  • Lysosomal Membrane
  • Early Endosome
  • Late Endosome
  • Centrosome
  • Cytoskeleton
  • Midbody
Molecular Function
  • Protein Binding
  • Zinc Ion Binding
  • Lipid Binding
  • Protein Kinase Binding
  • Phosphatidylinositol-3-phosphate Binding
  • Metal Ion Binding
Biological Process
  • Mitotic Cytokinesis
  • Double-strand Break Repair Via Homologous Recombination
  • DNA Repair
  • DNA Damage Response
  • Lysosome Organization
  • Regulation Of Cytokinesis
  • Cell Division
  • Autophagosome Organization
Pathways
Drugs
Diseases
  • Hereditary spastic paraplegia (SPG)
GWAS
  • Amyotrophic lateral sclerosis (sporadic) ( 24529757)
  • Asthma ( 31959851)
  • Asthma (childhood onset) ( 31036433)
Interacting Genes 36 interacting genes: ALAS1 ASB15 CBY2 CCDC125 CCDC136 CEP44 CFTR GOLGA2 GPRASP2 HMBOX1 HNRNPC HOOK2 KRT15 KRT27 KRT34 KRT40 KRTAP10-3 KRTAP10-7 KRTAP10-9 MAGED1 MDFI PLEKHF2 PNMA1 PNMA5 PPP1R16A PRDM6 SPAG5 SSX2IP TADA2A TCEANC TDO2 TFIP11 TRAF1 TTC23 USHBP1 USP20
Entrez ID 23503
HPRD ID 15734
Ensembl ID ENSG00000072121
Uniprot IDs Q68DK2
PDB IDs
Enriched GO Terms of Interacting Partners?
  • Keratin Filament
  • Intermediate Filament
  • Identical Protein Binding
  • Structural Constituent Of Skin Epidermis
  • Intermediate Filament Organization
  • Intermediate Filament Cytoskeleton Organization
  • Intermediate Filament-based Process
  • Centrosome Cycle
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