EFCAB3 and SPECC1L

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		EFCAB3	SPECC1L
Description		EF-hand calcium binding domain 3	sperm antigen with calponin homology and coiled-coil domains 1 like
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Cytoplasm Microtubule Organizing Center Spindle Cytoskeleton Cell-cell Junction Gap Junction Actin Cytoskeleton Microtubule Cytoskeleton Filamentous Actin Anchoring Junction
	Molecular Function	Calcium Ion Binding Protein Binding Metal Ion Binding	Protein Binding Beta-catenin Binding
	Biological Process		Negative Regulation Of Microtubule Depolymerization Cell Adhesion Cell Migration Actin Cytoskeleton Organization Negative Regulation Of Actin Filament Depolymerization Adherens Junction Organization Neural Crest Cell Delamination Cell Division Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Anterior Neural Tube Closure
Pathways
Drugs
Diseases
GWAS		Objective response to lithium treatment ( 26503763)	Acne (severe) ( 24927181 30542056) Caffeine consumption from tea ( 33287642) Coronary artery disease ( 29212778 32469254) Kawasaki disease ( 33692975) Mean reticulocyte volume ( 32888494) Severity of nausea and vomiting of pregnancy ( 29563502)
Interacting Genes		9 interacting genes: CBY2 GPRASP2 HPRT1 KRT34 KRT35 OXER1 SPECC1L TTC23 WWP2	11 interacting genes: APC ECPAS EFCAB3 ELOA GLIS2 PPP1R12C SNW1 UBC UBE2I ZFHX3 ZNF250
Entrez ID		146779	23384
HPRD ID		08077	11080
Ensembl ID		ENSG00000172421	ENSG00000100014
Uniprot IDs		Q8N7B9	B2RMV2 Q69YQ0
PDB IDs
Enriched GO Terms of Interacting Partners?		Guanine Salvage Hypoxanthine Salvage Hypoxanthine Phosphoribosyltransferase Activity Guanine Phosphoribosyltransferase Activity Structural Constituent Of Skin Epidermis Intermediate Filament Cytoskeleton Organization Keratin Filament Intermediate Filament-based Process Intermediate Filament Organization Neural Crest Cell Delamination 5-hydroxy-6E,8Z,11Z,14Z-icosatetraenoic Acid Binding 5(S)-hydroxyperoxy-6E,8Z,11Z,14Z-icosatetraenoic Acid Binding 5-oxo-6E,8Z,11Z,14Z-icosatetraenoic Acid Binding Adenine Metabolic Process Hypoxanthine Biosynthetic Process Hypoxanthine Metabolic Process Anterior Neural Tube Closure Guanine Metabolic Process GMP Salvage GMP Catabolic Process IMP Salvage Positive Regulation Of Dopamine Metabolic Process AMP Salvage Intermediate Filament Negative Regulation Of Potassium Ion Export Across Plasma Membrane Purine Ribonucleoside Salvage Structural Molecule Activity
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?