CIDEA and CIDEB

Number of citations of the paper that reports this interaction (PMID 10837461)
15

Data Source:
HPRD (in vivo)

		CIDEA	CIDEB
Gene Name		cell death-inducing DFFA-like effector a	cell death-inducing DFFA-like effector b
Image
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Mitochondrion Mitochondrial Envelope Lipid Particle	Lipid Particle Cytosol Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Homodimerization Activity	Protein Binding Identical Protein Binding
	Biological Process	Temperature Homeostasis Transcription, DNA-templated Regulation Of Transcription, DNA-templated Lipid Metabolic Process Apoptotic Process Cell Death Positive Regulation Of Sequestering Of Triglyceride Lipid Storage Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Tumor Necrosis Factor Production Response To Stilbenoid Regulation Of Apoptotic Process Negative Regulation Of Cytokine Secretion Negative Regulation Of Lipid Catabolic Process Negative Regulation Of Execution Phase Of Apoptosis Regulation Of Apoptotic DNA Fragmentation	Apoptotic Process Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Positive Regulation Of Cell Death Regulation Of Apoptotic Process Positive Regulation Of Release Of Cytochrome C From Mitochondria Execution Phase Of Apoptosis Activation Of Cysteine-type Endopeptidase Activity
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		3 interactors: CIDEB UCP1 ZBTB16	3 interactors: CIDEA DFFA DFFB
Entrez ID		1149	27141
HPRD ID		08380	11981
Ensembl ID			ENSG00000136305
Uniprot IDs		O60543 Q8N5P9	Q9UHD4
PDB IDs		2EEL	1D4B
Enriched GO Terms of Interacting Partners?		Positive Regulation Of NK T Cell Differentiation Male Germ-line Stem Cell Asymmetric Division	Regulation Of Apoptotic DNA Fragmentation Negative Regulation Of Execution Phase Of Apoptosis Apoptotic DNA Fragmentation Regulation Of Execution Phase Of Apoptosis Apoptotic Nuclear Changes Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Execution Phase Of Apoptosis DNA Catabolic Process, Endonucleolytic Apoptotic Process Programmed Cell Death Cell Death Death DNA Catabolic Process Negative Regulation Of Apoptotic DNA Fragmentation Nucleic Acid Phosphodiester Bond Hydrolysis Apoptotic Chromosome Condensation Positive Regulation Of Sequestering Of Triglyceride Thymocyte Apoptotic Process Aromatic Compound Catabolic Process Response To Stilbenoid T Cell Apoptotic Process Negative Regulation Of Lipid Catabolic Process Temperature Homeostasis Cellular Macromolecule Catabolic Process Positive Regulation Of Lipid Storage Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Negative Regulation Of Cytokine Secretion Negative Regulation Of Cell Death Negative Regulation Of Tumor Necrosis Factor Production Lipid Storage Negative Regulation Of Tumor Necrosis Factor Superfamily Cytokine Production DNA Metabolic Process Chromosome Condensation Regulation Of Lipid Catabolic Process Regulation Of Lipid Storage Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Lipid Metabolic Process Regulation Of Apoptotic Process Regulation Of Tumor Necrosis Factor Production Regulation Of Cell Death Negative Regulation Of DNA Metabolic Process Negative Regulation Of Protein Secretion Nitrogen Compound Metabolic Process Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Tagcloud ?		acot11 adipose adiposity beige bfit brite brown chow contributor cpt1beta dexa dio2 ehmt1 erralpha lean littermates orphan pparalpha prdm16 resist roralpha sg stabilizes staggerer thermogenesis thermogenic thermography ucp1 uncoupling	87mg ags alteration arrayed bad bcl2 bcl2l11 bfar bnip3l casp7 cidea combat endows exceptions irrelevant oct4 oct4b1 pluripotent sirnas spliced stream tenfold tnfrsf10b tnfrsf11b tnfrsf1a tnfrsf21 tp73 traf3 uncovering
Tagcloud (Difference) ?		acot11 adipose adiposity beige bfit brite brown chow contributor cpt1beta dexa dio2 ehmt1 erralpha lean littermates orphan pparalpha prdm16 resist roralpha sg stabilizes staggerer thermogenesis thermogenic thermography ucp1 uncoupling	87mg ags alteration arrayed bad bcl2 bcl2l11 bfar bnip3l casp7 combat endows exceptions irrelevant oct4 oct4b1 pluripotent sirnas spliced stream tenfold tnfrsf10b tnfrsf11b tnfrsf1a tnfrsf21 tp73 traf3 uncovering
Tagcloud (Intersection) ?		cidea