CIDEA and CIDEC

Number of citations of the paper that reports this interaction (PubMedID 19843876)
0

Data Source:
BioGRID (affinity chromatography technology, two hybrid)

		CIDEA	CIDEC
Description		cell death inducing DFFA like effector a	cell death inducing DFFA like effector c
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Mitochondrion Mitochondrial Envelope Lipid Droplet Cytosol	Nucleus Endoplasmic Reticulum Lipid Droplet Cytosol
	Molecular Function	Protein Homodimerization Activity Phosphatidic Acid Binding Lipid Transfer Activity	Protein Binding Phosphatidic Acid Binding Lipid Transfer Activity Molecular Condensate Scaffold Activity
	Biological Process	Temperature Homeostasis Negative Regulation Of Cytokine Production Lipid Metabolic Process Apoptotic Process Lipid Storage Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Tumor Necrosis Factor Production Response To Stilbenoid Fat Cell Differentiation Negative Regulation Of Lipid Catabolic Process Negative Regulation Of Multicellular Organismal Process Regulation Of Macromolecule Metabolic Process Cellular Response To Cold Intermembrane Lipid Transfer Negative Regulation Of Cold-induced Thermogenesis Lipid Droplet Fusion Negative Regulation Of Execution Phase Of Apoptosis Regulation Of Apoptotic DNA Fragmentation	Lipid Transport Apoptotic Process Lipid Storage Lipid Droplet Organization Negative Regulation Of Lipid Catabolic Process Negative Regulation Of Triglyceride Metabolic Process Execution Phase Of Apoptosis Intermembrane Lipid Transfer Lipid Droplet Fusion
Pathways		Lipid particle organization Transcriptional regulation of brown and beige adipocyte differentiation by EBF2	Lipid particle organization MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis
Drugs
Diseases
GWAS		Antipsychotic drug-induced weight gain in schizophrenia ( 31447353) Attention deficit hyperactivity disorder (inattention symptoms) ( 32595297)
Interacting Genes		5 interacting genes: CIDEB CIDEC MIEF2 UCP1 ZBTB16	7 interacting genes: CIDEA KLHL20 METTL15 NR0B2 SPATA12 UFSP1 ZBTB42
Entrez ID		1149	63924
HPRD ID		08380	13060
Ensembl ID		ENSG00000176194	ENSG00000187288
Uniprot IDs		B3KVA2 O60543 Q8N5P9	A0A0A0MRY9 Q96AQ7
PDB IDs		2EEL
Enriched GO Terms of Interacting Partners?		Lipid Droplet Fusion Lipid Transfer Activity Organelle Fusion Execution Phase Of Apoptosis Phosphatidic Acid Binding Lipid Storage Intermembrane Lipid Transfer Regulation Of Triglyceride Metabolic Process Lipid Droplet Organization Cellular Response To Dehydroepiandrosterone Purine Ribonucleotide Binding Lipid Droplet Type 2 Angiotensin Receptor Binding Response To Dehydroepiandrosterone Male Germ-line Stem Cell Asymmetric Division Long-chain Fatty Acid Binding Oxidative Phosphorylation Uncoupler Activity Anion Binding Germ-line Stem Cell Division Cell Death Apoptotic Process Programmed Cell Death Positive Regulation Of NK T Cell Differentiation Regulation Of NK T Cell Differentiation Ossification Involved In Bone Maturation Diet Induced Thermogenesis Lipid Transport Very-low-density Lipoprotein Particle Assembly Cardiolipin Binding Regulation Of Lipid Metabolic Process Cellular Response To Cold Mesonephros Development Asymmetric Cell Division COPI-coated Vesicle Negative Regulation Of Triglyceride Metabolic Process Mitochondrial Envelope COPII Vesicle Coat COPII-coated Vesicle Cargo Loading Mitochondrial Fusion Positive Regulation Of Chondrocyte Differentiation Mitochondrial Transmembrane Transport Positive Regulation Of Mitochondrial Fission Adaptive Thermogenesis Plasma Lipoprotein Particle Assembly Proton Transmembrane Transporter Activity Stem Cell Division Protein-lipid Complex Assembly Negative Regulation Of Lipid Catabolic Process Response To Nutrient Levels Positive Regulation Of Protein Targeting To Membrane
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