CA12 and RDH11

Number of citations of the paper that reports this interaction (PubMedID 21900206)
0

Data Source:
BioGRID (two hybrid)

		CA12	RDH11
Description		carbonic anhydrase 12	retinol dehydrogenase 11
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Basolateral Plasma Membrane Apical Plasma Membrane	Photoreceptor Inner Segment Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane
	Molecular Function	Carbonate Dehydratase Activity Zinc Ion Binding Lyase Activity Metal Ion Binding	All-trans-retinol Dehydrogenase (NAD+) Activity Protein Binding Oxidoreductase Activity Oxidoreductase Activity, Acting On The CH-OH Group Of Donors, NAD Or NADP As Acceptor Aldehyde Dehydrogenase (NADP+) Activity All-trans-retinol Dehydrogenase (NADP+) Activity 11-cis-retinol Dehydrogenase (NADP+) Activity
	Biological Process	Estrous Cycle Chloride Ion Homeostasis	Retinoid Metabolic Process Lipid Metabolic Process Visual Perception Retinol Metabolic Process Retinal Metabolic Process Cellular Detoxification Of Aldehyde
Pathways		Reversible hydration of carbon dioxide	The canonical retinoid cycle in rods (twilight vision) RA biosynthesis pathway Retinoid metabolism and transport
Drugs		Benzthiazide Hydroflumethiazide Acetazolamide Zonisamide Ellagic acid	Vitamin A
Diseases
GWAS		Daytime nap ( 33568662) Dentures ( 31235808) Number of decayed, missing and filled tooth surfaces ( 31235808) Number of decayed, missing and filled tooth surfaces or use of dentures ( 31235808) Refractive error ( 32231278)
Interacting Genes		10 interacting genes: ATP5F1C CUX1 DAXX KATNBL1 LGALS7 MAPK6 MRPL9 RDH11 SGSM2 TOE1	5 interacting genes: BLOC1S2 CA12 ROBO2 SELENOF TMEM31
Entrez ID		771	51109
HPRD ID		04464	09707
Ensembl ID		ENSG00000074410	ENSG00000072042
Uniprot IDs		B3KUB4 O43570	A0A0S2Z583 Q8TC12
PDB IDs		1JCZ 1JD0 4HT2 4KP5 4KP8 4Q0L 4QJ0 4QJO 4QJW 4WW8 5LL5 5LL9 5LLO 5LLP 5MSA 5MSB 6G5L 6G7A 6QN0 6QNG 6QNL 6R6Y 6R71 6RPS 6T5P 6T5Q 7PP9 7PUU 7PUV 7PUW 8CO3
Enriched GO Terms of Interacting Partners?			Chloride Ion Homeostasis Estrous Cycle Carbonate Dehydratase Activity Ovulation Cycle Negative Regulation Of Negative Chemotaxis Olfactory Bulb Interneuron Development Endocardial Cushion Formation Apoptotic Process Involved In Luteolysis Heart Induction Axon Guidance Receptor Activity Negative Regulation Of Synapse Organization Axon Midline Choice Point Recognition Regulation Of Negative Chemotaxis Axon Choice Point Recognition Negative Regulation Of Synapse Assembly Pulmonary Valve Morphogenesis Regulation Of Heart Morphogenesis Axolemma Selenium Binding Sperm DNA Condensation 'de Novo' Post-translational Protein Folding 'de Novo' Protein Folding Thioredoxin Peroxidase Activity Anterograde Synaptic Vesicle Transport Gamma-tubulin Complex Regulation Of Endosome Size Cytoplasmic Side Of Lysosomal Membrane Regulation Of Lysosome Size Positive Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process Mitochondrial Outer Membrane Permeabilization Involved In Programmed Cell Death Regulation Of Vesicle Size BORC Complex BLOC-1 Complex Mitochondrial Outer Membrane Permeabilization Monoatomic Anion Homeostasis Retinal Ganglion Cell Axon Guidance Forebrain Neuron Development Organ Induction Platelet Dense Granule Organization Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process Neuron Projection Development Outflow Tract Septum Morphogenesis Positive Regulation Of Mitochondrial Membrane Permeability
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