GABRG2 and ZDHHC3

Number of citations of the paper that reports this interaction (PMID 15229235)
53

Data Source:
HPRD (two hybrid, in vivo, in vitro)

		GABRG2	ZDHHC3
Gene Name		gamma-aminobutyric acid (GABA) A receptor, gamma 2	zinc finger, DHHC-type containing 3
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane Cell Junction Axon Dendrite Membrane Chloride Channel Complex Postsynaptic Membrane Inhibitory Synapse GABA-A Receptor Complex	Golgi Membrane Golgi Apparatus Membrane Integral Component Of Membrane
	Molecular Function	GABA-A Receptor Activity Extracellular Ligand-gated Ion Channel Activity Chloride Channel Activity Protein Binding Benzodiazepine Receptor Activity	Zinc Ion Binding Palmitoyltransferase Activity Protein-cysteine S-palmitoyltransferase Activity
	Biological Process	Transport Gamma-aminobutyric Acid Signaling Pathway Synaptic Transmission Post-embryonic Development Adult Behavior Ion Transmembrane Transport Synaptic Transmission, GABAergic Transmembrane Transport Cellular Response To Histamine Chloride Transmembrane Transport	Protein Targeting Protein Palmitoylation
Pathways		GABA receptor activation Ion channel transport GABA A receptor activation Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell Ligand-gated ion channel transport Orphan transporters Transmission across Chemical Synapses
Drugs
Diseases
GWAS
Protein-Protein Interactions		6 interactors: DRD5 GABARAP PPP3CA PRKCA PRKCB ZDHHC3	5 interactors: EWSR1 GABRG2 NEDD4L SMAD1 UBQLN4
Entrez ID		2566	51304
HPRD ID		00663	15718
Ensembl ID		ENSG00000113327
Uniprot IDs		P18507	Q9NYG2
PDB IDs
Enriched GO Terms of Interacting Partners?		Histone H3-T6 Phosphorylation Synaptic Transmission Cell-cell Signaling Cellular Response To Carbohydrate Stimulus Cellular Chemical Homeostasis Positive Regulation Of Cardiac Muscle Hypertrophy Negative Regulation Of Glucose Transport Response To Carbohydrate Cellular Homeostasis Regulation Of Cardiac Muscle Hypertrophy Activation Of Adenylate Cyclase Activity Chemical Homeostasis Response To Amphetamine Mitotic Nuclear Envelope Disassembly Positive Regulation Of Adenylate Cyclase Activity Cellular Calcium Ion Homeostasis Negative Regulation Of Insulin Receptor Signaling Pathway Calcium Ion Homeostasis Histone Phosphorylation Nuclear Envelope Disassembly Positive Regulation Of Lyase Activity Peptidyl-threonine Phosphorylation Response To Amine Regulation Of Adenylate Cyclase Activity Negative Regulation Of Signaling Negative Regulation Of Transport Cellular Metal Ion Homeostasis Positive Regulation Of CAMP Biosynthetic Process Protein Targeting Regulation Of Insulin Receptor Signaling Pathway Regulation Of Cyclase Activity Nuclear Envelope Organization Positive Regulation Of CAMP Metabolic Process Cellular Cation Homeostasis Cellular Ion Homeostasis Metal Ion Homeostasis Homeostatic Process Protein Transport Regulation Of Cellular Response To Insulin Stimulus Positive Regulation Of Cyclic Nucleotide Metabolic Process Establishment Of Protein Localization Regulation Of CAMP Biosynthetic Process Cell Surface Receptor Signaling Pathway Ion Homeostasis Regulation Of Glucose Transport Transition Between Fast And Slow Fiber Positive Regulation Of Dense Core Granule Biogenesis Vascular Endothelial Growth Factor Receptor Signaling Pathway Regulation Of CAMP Metabolic Process Wound Healing	Transforming Growth Factor Beta Receptor Signaling Pathway Positive Regulation Of Caveolin-mediated Endocytosis Cellular Response To Transforming Growth Factor Beta Stimulus Response To Transforming Growth Factor Beta Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Regulation Of Caveolin-mediated Endocytosis Primary MiRNA Processing Negative Regulation Of Sodium Ion Transmembrane Transporter Activity Negative Regulation Of Sodium Ion Transmembrane Transport Osteoblast Fate Commitment Negative Regulation Of Protein Localization To Cell Surface Negative Regulation Of Potassium Ion Transmembrane Transporter Activity Regulation Of Tight Junction Assembly Cellular Response To Histamine Synaptic Transmission, GABAergic Negative Regulation Of Sodium Ion Transport SMAD Protein Complex Assembly Response To Histamine Regulation Of Protein Catabolic Process Negative Regulation Of Potassium Ion Transmembrane Transport Cellular Sodium Ion Homeostasis Cellular Response To Organic Cyclic Compound Mesodermal Cell Fate Commitment Ventricular Cardiac Muscle Cell Action Potential Regulation Of Protein Localization To Cell Surface Cardiac Muscle Cell Proliferation Cellular Response To Organic Substance Cellular Response To Ammonium Ion Negative Regulation Of Potassium Ion Transport Negative Regulation Of Systemic Arterial Blood Pressure Production Of MiRNAs Involved In Gene Silencing By MiRNA Cellular Response To BMP Stimulus Regulation Of Membrane Repolarization Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Sodium Ion Homeostasis Mesodermal Cell Differentiation Cardiac Muscle Cell Action Potential Involved In Contraction Regulation Of Potassium Ion Transmembrane Transporter Activity Cellular Response To Growth Factor Stimulus Response To Growth Factor Gamma-aminobutyric Acid Signaling Pathway Cell Fate Commitment Involved In Formation Of Primary Germ Layer Regulation Of Sodium Ion Transmembrane Transporter Activity Cardiac Muscle Tissue Growth Positive Regulation Of Cation Channel Activity Negative Regulation Of Muscle Cell Apoptotic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Cellular Response To Chemical Stimulus Positive Regulation Of Dendrite Morphogenesis Gene Silencing By MiRNA Positive Regulation Of Sodium Ion Transport
Tagcloud ?		agonistic alpha6 aminobutyric antiepileptic beta3 compromise dravet dysfunctions epilepsy gabaa gabra1 gabra6 gabrb3 gabrd gamma2 gastaut gated gating hyperpolarization infantile insufficiencies lennox myoclonic nonsense pathomechanisms pentamers seizures spasms
Tagcloud (Difference) ?		agonistic alpha6 aminobutyric antiepileptic beta3 compromise dravet dysfunctions epilepsy gabaa gabra1 gabra6 gabrb3 gabrd gamma2 gastaut gated gating hyperpolarization infantile insufficiencies lennox myoclonic nonsense pathomechanisms pentamers seizures spasms
Tagcloud (Intersection) ?