L3MBTL1 and HIST1H1B

Number of citations of the paper that reports this interaction (PMID 17540172)
97

Data Source:
HPRD (in vitro, in vivo)

		L3MBTL1	HIST1H1B
Gene Name		l(3)mbt-like 1 (Drosophila)	histone cluster 1, H1b
Image
Gene Ontology Annotations	Cellular Component	Chromatin Condensed Chromosome Nucleus Nucleoplasm Nucleolus Plasma Membrane	Nucleosome Nuclear Chromatin Nuclear Heterochromatin Extracellular Vesicular Exosome
	Molecular Function	Chromatin Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Zinc Ion Binding Nucleosome Binding Nucleosomal Histone Binding SAM Domain Binding Methylated Histone Binding Histone Binding Identical Protein Binding	Chromatin DNA Binding Histone Deacetylase Binding Poly(A) RNA Binding
	Biological Process	Transcription, DNA-templated Regulation Of Mitotic Nuclear Division Chromatin Modification Hemopoiesis Regulation Of Megakaryocyte Differentiation Negative Regulation Of Transcription, DNA-templated Regulation Of Cell Cycle	Negative Regulation Of Transcription From RNA Polymerase II Promoter Chromatin Organization Nucleosome Assembly Positive Regulation Of Cell Growth Protein Stabilization Positive Regulation Of Histone H3-K9 Methylation Establishment Of Protein Localization To Chromatin
Pathways			DNA Damage/Telomere Stress Induced Senescence Formation of Senescence-Associated Heterochromatin Foci (SAHF) Activation of DNA fragmentation factor Apoptosis induced DNA fragmentation Cellular Senescence Programmed Cell Death Apoptotic execution phase
Drugs
Diseases
GWAS
Protein-Protein Interactions		7 interactors: CBX3 ETV6 ETV7 HIST1H1B HIST4H4 RB1 SETD7	26 interactors: CBX5 CCNA1 CCNA2 CCNB1 CCNE1 CDK1 CDK2 CDK5 CDKN1A CDKN1B EHMT2 IRAK4 KAT2A KAT2B L3MBTL1 LOX MELK MLLT1 NSD1 PRKCA PRKCB PRKCD PRKCZ RPS6KA5 SERPINH1 SIRT1
Entrez ID		26013	3009
HPRD ID		16387	00821
Ensembl ID		ENSG00000185513	ENSG00000184357
Uniprot IDs		Q9Y468	P16401
PDB IDs		1OYX 1OZ2 1OZ3 2PQW 2RHI 2RHU 2RHX 2RHY 2RHZ 2RI2 2RI3 2RI5 2RJC 2RJD 2RJE 2RJF 3OQ5 3P8H 3UWN	2FE2 2RHI
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Chromatin Organization Chromosome Organization Negative Regulation Of Cellular Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Chromatin Modification Chromatin Remodeling Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Protein Localization To Chromosome Negative Regulation Of Transcription From RNA Polymerase II Promoter Gene Expression Transcription, DNA-templated RNA Biosynthetic Process Nucleobase-containing Compound Metabolic Process Regulation Of Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nucleosome Assembly Negative Regulation Of Transcription From RNA Polymerase II Promoter During Mitosis Sister Chromatid Biorientation Chromatin Assembly Organelle Organization Nucleosome Organization RNA Metabolic Process Chromatin Assembly Or Disassembly Regulation Of Centromere Complex Assembly Histone H4-K20 Demethylation Negative Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle Nitrogen Compound Metabolic Process Protein-DNA Complex Assembly Regulation Of Transcription From RNA Polymerase II Promoter Maintenance Of Mitotic Sister Chromatid Cohesion Regulation Of Cohesin Localization To Chromatin Regulation Of Myeloid Cell Differentiation DNA Packaging Cellular Macromolecule Biosynthetic Process Negative Regulation Of Megakaryocyte Differentiation Attachment Of Mitotic Spindle Microtubules To Kinetochore Macromolecule Biosynthetic Process Regulation Of Chromosome Organization Establishment Of Protein Localization To Chromatin	Regulation Of Protein Kinase Activity Regulation Of Kinase Activity Regulation Of Protein Phosphorylation Histone Modification Peptidyl-amino Acid Modification Chromatin Modification Regulation Of Phosphorylation Regulation Of Cellular Protein Metabolic Process Cell Cycle Regulation Of Cell Cycle Regulation Of Phosphorus Metabolic Process Regulation Of Protein Metabolic Process Chromatin Organization Histone Phosphorylation Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Regulation Of Nitrogen Compound Metabolic Process Cellular Protein Modification Process Regulation Of Mitotic Cell Cycle Cell Cycle Process Negative Regulation Of Protein Phosphorylation Negative Regulation Of Cellular Metabolic Process G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Process Regulation Of Gene Expression Mitotic Cell Cycle Chromosome Organization Regulation Of Catalytic Activity Negative Regulation Of Phosphorylation Protein Phosphorylation G1/S Transition Of Mitotic Cell Cycle Negative Regulation Of Cellular Protein Metabolic Process Response To Stress Response To Organic Substance Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Protein Metabolic Process Protein Metabolic Process Response To Wounding Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Cellular Protein Metabolic Process Peptidyl-threonine Phosphorylation Peptidyl-serine Phosphorylation Regulation Of RNA Metabolic Process Negative Regulation Of Protein Kinase Activity Regulation Of Metabolic Process Regulation Of Insulin Receptor Signaling Pathway Negative Regulation Of Kinase Activity Positive Regulation Of Cell Proliferation Negative Regulation Of Protein Serine/threonine Kinase Activity Wound Healing
Tagcloud ?		advances alterations asxl1 discovery driving epigenetic existence idh1 idh2 jak leukemic modifiers modify modifying mpn mpns myeloproliferative neoplasms nevertheless predate predominant prmt5 reading reviews stat suspected technologies tet2 translational
Tagcloud (Difference) ?		advances alterations asxl1 discovery driving epigenetic existence idh1 idh2 jak leukemic modifiers modify modifying mpn mpns myeloproliferative neoplasms nevertheless predate predominant prmt5 reading reviews stat suspected technologies tet2 translational
Tagcloud (Intersection) ?