SLX1B

Description		structure-specific endonuclease subunit SLX1B
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Slx1-Slx4 Complex
	Molecular Function	Nuclease Activity Endonuclease Activity Protein Binding Zinc Ion Binding Crossover Junction DNA Endonuclease Activity Hydrolase Activity 5'-flap Endonuclease Activity Metal Ion Binding
	Biological Process	Double-strand Break Repair Via Homologous Recombination DNA Repair DNA Recombination DNA Damage Response DNA Double-strand Break Processing Involved In Repair Via Single-strand Annealing Telomere Maintenance Via Telomere Lengthening Regulation Of Telomere Maintenance Telomeric D-loop Disassembly T-circle Formation Negative Regulation Of Telomere Maintenance Via Telomere Lengthening Positive Regulation Of T-circle Formation
Pathways		Resolution of D-loop Structures through Holliday Junction Intermediates Fanconi Anemia Pathway
Drugs
Diseases
GWAS
Novel Interacting Genes		1 novel interacting genes: DCTPP1
Interacting Genes		3 interacting genes: DUSP10 THAP11 TUBA1B
Entrez ID		79008
HPRD ID		14673
Ensembl ID		ENSG00000181625
Uniprot IDs		Q9BQ83
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Epithelium Regeneration DTTP Catabolic Process DCTP Diphosphatase Activity DCTP Catabolic Process Pyrimidine Deoxyribonucleotide Binding Regulation Of Epithelium Regeneration Negative Regulation Of Respiratory Burst Involved In Inflammatory Response Negative Regulation Of Respiratory Burst Mitogen-activated Protein Kinase P38 Binding MAP Kinase Phosphatase Activity MAP Kinase Tyrosine Phosphatase Activity Nucleoside Triphosphate Diphosphatase Activity DNA Protection Protein Tyrosine/threonine Phosphatase Activity Regulation Of Respiratory Burst Involved In Inflammatory Response JUN Kinase Binding Negative Regulation Of P38MAPK Cascade Negative Regulation Of Stress-activated Protein Kinase Signaling Cascade Negative Regulation Of Stress-activated MAPK Cascade Regulation Of Mitochondrial Transcription Nucleoside Triphosphate Catabolic Process Pyrophosphatase Activity Hydrolase Activity Negative Regulation Of Oligodendrocyte Differentiation MAP Kinase Tyrosine/serine/threonine Phosphatase Activity Negative Regulation Of Epithelial Cell Migration Pyrimidine Deoxyribonucleotide Catabolic Process Regulation Of Respiratory Burst Cellular Response To Interleukin-4 Positive Regulation Of Regulatory T Cell Differentiation Regulation Of Brown Fat Cell Differentiation Negative Regulation Of Glial Cell Differentiation Stress-activated Protein Kinase Signaling Cascade Stress-activated MAPK Cascade Pyrimidine-containing Compound Catabolic Process Response To Interleukin-4 Deoxyribose Phosphate Catabolic Process Deoxyribonucleotide Catabolic Process
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