BAZ1A and XRCC5

Number of citations of the paper that reports this interaction (PMID 21172662)
34

Data Source:
BioGRID (affinity chromatography technology, pull down)

		BAZ1A	XRCC5
Gene Name		bromodomain adjacent to zinc finger domain, 1A	X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nuclear Chromosome CHRAC ACF Complex	Nuclear Telomere Cap Complex Nuclear Chromosome, Telomeric Region Nucleus Nucleoplasm Nucleolus Cytosol Plasma Membrane Membrane Ku70:Ku80 Complex Nonhomologous End Joining Complex
	Molecular Function	Histone Acetyltransferase Activity Protein Binding Zinc Ion Binding	DNA Binding Damaged DNA Binding Double-stranded DNA Binding Double-stranded Telomeric DNA Binding ATP-dependent DNA Helicase Activity Protein Binding ATP Binding Protein C-terminus Binding Ubiquitin Protein Ligase Binding Telomeric DNA Binding Transcription Regulatory Region DNA Binding Poly(A) RNA Binding 5'-deoxyribose-5-phosphate Lyase Activity
	Biological Process	DNA-dependent DNA Replication Chromatin Remodeling Transcription, DNA-templated Regulation Of Transcription, DNA-templated	Telomere Maintenance DNA Repair Double-strand Break Repair Double-strand Break Repair Via Nonhomologous End Joining DNA Recombination Transcription, DNA-templated Brain Development Cell Proliferation Viral Process Positive Regulation Of Type I Interferon Production DNA Duplex Unwinding Response To Drug Innate Immune Response Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Neurogenesis Hematopoietic Stem Cell Differentiation Cellular Response To Fatty Acid Cellular Hyperosmotic Salinity Response Cellular Response To X-ray Establishment Of Integrated Proviral Latency
Pathways			Cytosolic sensors of pathogen-associated DNA HIV Infection Processing of DNA ends prior to end rejoining Integration of provirus Early Phase of HIV Life Cycle HIV Life Cycle Nonhomologous End-joining (NHEJ) STING mediated induction of host immune responses Double-Strand Break Repair IRF3-mediated induction of type I IFN 2-LTR circle formation Innate Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		9 interactors: CHRAC1 NCOR1 POLE3 SATB1 SMAD2 SMAD9 SMARCA5 XRCC5 XRCC6	47 interactors: APEX1 APLF AR ATM ATR BAZ1A BRCA1 CD40 CDC16 CEBPA CHAF1A COIL CSNK2A1 ELF3 GZMA GZMB HSF1 LIG3 MSX2 NAA15 NBN NCOA6 NDRG1 ORC2 PARP1 PCNA PDX1 PGR POLA1 POLD1 POLE POLR2A PRKDC RBM14 RUNX2 SGOL1 SUMO1 SUPT4H1 SUPT5H TCF4 TERF2IP TERT TOP2B TYK2 VAV1 WRN XRCC6
Entrez ID		11177	7520
HPRD ID		12034	08935
Ensembl ID		ENSG00000198604	ENSG00000079246
Uniprot IDs		Q9NRL2	P13010
PDB IDs			1JEQ 1JEY 1Q2Z 1RW2 3RZ9
Enriched GO Terms of Interacting Partners?		Chromosome Organization Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Cellular Hyperosmotic Salinity Response Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Cellular Response To X-ray Chromatin Modification Negative Regulation Of Gene Expression Nitrogen Compound Metabolic Process Negative Regulation Of Biosynthetic Process Transcription, DNA-templated Chromatin Organization Establishment Of Integrated Proviral Latency RNA Biosynthetic Process Cellular Hyperosmotic Response Hyperosmotic Salinity Response Establishment Of Viral Latency Cellular Response To Salt Stress Regulation Of Transcription From RNA Polymerase II Promoter Transforming Growth Factor Beta Receptor Signaling Pathway DNA Metabolic Process Double-strand Break Repair Organelle Organization RNA Metabolic Process Double-strand Break Repair Via Nonhomologous End Joining Hyperosmotic Response Negative Regulation Of Cellular Metabolic Process Cellular Response To Transforming Growth Factor Beta Stimulus Chromatin Remodeling Gene Expression Response To Transforming Growth Factor Beta Cellular Response To Osmotic Stress Response To X-ray DNA-templated Transcription, Initiation CD4-positive, Alpha-beta T Cell Differentiation Immune System Development Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway CD4-positive, Alpha-beta T Cell Activation Response To Salt Stress Brain Development DNA Conformation Change Head Development Regulation Of Transcription, DNA-templated	DNA Metabolic Process Telomere Maintenance DNA Replication DNA Recombination DNA Repair Cellular Response To DNA Damage Stimulus Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Nitrogen Compound Metabolic Process Cellular Response To Stress Double-strand Break Repair Regulation Of Nitrogen Compound Metabolic Process Response To Stress Chromosome Organization Biosynthetic Process DNA-dependent DNA Replication Positive Regulation Of Metabolic Process Negative Regulation Of Cellular Metabolic Process Organelle Organization Regulation Of Metabolic Process Cell Cycle Telomere Maintenance Via Telomere Lengthening Positive Regulation Of Cellular Metabolic Process Regulation Of RNA Metabolic Process RNA Biosynthetic Process RNA Metabolic Process Regulation Of Gene Expression Positive Regulation Of Gene Expression Cellular Response To Stimulus Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Response To Stimulus Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Cellular Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Transcription, DNA-templated Mitotic Recombination Transcription, DNA-templated Positive Regulation Of Cellular Biosynthetic Process DNA Strand Elongation Base-excision Repair Transcription From RNA Polymerase II Promoter Cell Cycle Process Negative Regulation Of Biosynthetic Process
Tagcloud ?		arid1a arid1b avenues carcinosarcoma carcinosarcomas dysregulation excluding exome gynaecological harboured inactivating kras landscape massively methyltransferase mismatch mll3 modifier mullerian mutational mutator perform personalized pi3 quarters remodelling spop thirds tumours	annotation bub california cruz databases david deterioration downloaded exploring geo gse27567 h17 hub inheritance mendelian networks omim omnibus ranked santa topological visualization xpc xrcc4 ybx1 yy1 zfhx3 zfp36 zmat3
Tagcloud (Difference) ?		arid1a arid1b avenues carcinosarcoma carcinosarcomas dysregulation excluding exome gynaecological harboured inactivating kras landscape massively methyltransferase mismatch mll3 modifier mullerian mutational mutator perform personalized pi3 quarters remodelling spop thirds tumours	annotation bub california cruz databases david deterioration downloaded exploring geo gse27567 h17 hub inheritance mendelian networks omim omnibus ranked santa topological visualization xpc xrcc4 ybx1 yy1 zfhx3 zfp36 zmat3
Tagcloud (Intersection) ?