XRCC5 and NAA15

Number of citations of the paper that reports this interaction (PMID 12145306)
20

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vitro)

		XRCC5	NAA15
Gene Name		X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)	N(alpha)-acetyltransferase 15, NatA auxiliary subunit
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nuclear Telomere Cap Complex Nuclear Chromosome, Telomeric Region Nucleus Nucleoplasm Nucleolus Cytosol Plasma Membrane Membrane Ku70:Ku80 Complex Nonhomologous End Joining Complex	Nucleus Transcription Factor Complex Cytoplasm Membrane NatA Complex
	Molecular Function	DNA Binding Damaged DNA Binding Double-stranded DNA Binding Double-stranded Telomeric DNA Binding ATP-dependent DNA Helicase Activity Protein Binding ATP Binding Protein C-terminus Binding Ubiquitin Protein Ligase Binding Telomeric DNA Binding Transcription Regulatory Region DNA Binding Poly(A) RNA Binding 5'-deoxyribose-5-phosphate Lyase Activity	Protein Binding N-acetyltransferase Activity Acetyltransferase Activity Ribosome Binding Poly(A) RNA Binding
	Biological Process	Telomere Maintenance DNA Repair Double-strand Break Repair Double-strand Break Repair Via Nonhomologous End Joining DNA Recombination Transcription, DNA-templated Brain Development Cell Proliferation Viral Process Positive Regulation Of Type I Interferon Production DNA Duplex Unwinding Response To Drug Innate Immune Response Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Neurogenesis Hematopoietic Stem Cell Differentiation Cellular Response To Fatty Acid Cellular Hyperosmotic Salinity Response Cellular Response To X-ray Establishment Of Integrated Proviral Latency	Angiogenesis Transcription, DNA-templated N-terminal Protein Amino Acid Acetylation Cell Differentiation Negative Regulation Of Apoptotic Process Positive Regulation Of Transcription, DNA-templated Protein Stabilization
Pathways		Cytosolic sensors of pathogen-associated DNA HIV Infection Processing of DNA ends prior to end rejoining Integration of provirus Early Phase of HIV Life Cycle HIV Life Cycle Nonhomologous End-joining (NHEJ) STING mediated induction of host immune responses Double-Strand Break Repair IRF3-mediated induction of type I IFN 2-LTR circle formation Innate Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		47 interactors: APEX1 APLF AR ATM ATR BAZ1A BRCA1 CD40 CDC16 CEBPA CHAF1A COIL CSNK2A1 ELF3 GZMA GZMB HSF1 LIG3 MSX2 NAA15 NBN NCOA6 NDRG1 ORC2 PARP1 PCNA PDX1 PGR POLA1 POLD1 POLE POLR2A PRKDC RBM14 RUNX2 SGOL1 SUMO1 SUPT4H1 SUPT5H TCF4 TERF2IP TERT TOP2B TYK2 VAV1 WRN XRCC6	6 interactors: NAA10 NAA11 NAA50 RPL26 XRCC5 XRCC6
Entrez ID		7520	80155
HPRD ID		08935	10471
Ensembl ID		ENSG00000079246	ENSG00000164134
Uniprot IDs		P13010	Q58F05 Q9BXJ9
PDB IDs		1JEQ 1JEY 1Q2Z 1RW2 3RZ9
Enriched GO Terms of Interacting Partners?		DNA Metabolic Process Telomere Maintenance DNA Replication DNA Recombination DNA Repair Cellular Response To DNA Damage Stimulus Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Nitrogen Compound Metabolic Process Cellular Response To Stress Double-strand Break Repair Regulation Of Nitrogen Compound Metabolic Process Response To Stress Chromosome Organization Biosynthetic Process DNA-dependent DNA Replication Positive Regulation Of Metabolic Process Negative Regulation Of Cellular Metabolic Process Organelle Organization Regulation Of Metabolic Process Cell Cycle Telomere Maintenance Via Telomere Lengthening Positive Regulation Of Cellular Metabolic Process Regulation Of RNA Metabolic Process RNA Biosynthetic Process RNA Metabolic Process Regulation Of Gene Expression Positive Regulation Of Gene Expression Cellular Response To Stimulus Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Response To Stimulus Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Cellular Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Transcription, DNA-templated Mitotic Recombination Transcription, DNA-templated Positive Regulation Of Cellular Biosynthetic Process DNA Strand Elongation Base-excision Repair Transcription From RNA Polymerase II Promoter Cell Cycle Process Negative Regulation Of Biosynthetic Process	N-terminal Protein Amino Acid Acetylation N-terminal Protein Amino Acid Modification Cellular Hyperosmotic Salinity Response N-terminal Peptidyl-glutamic Acid Acetylation N-terminal Peptidyl-serine Acetylation Cellular Response To X-ray Establishment Of Integrated Proviral Latency Cellular Hyperosmotic Response Hyperosmotic Salinity Response Establishment Of Viral Latency Cellular Response To Salt Stress Internal Protein Amino Acid Acetylation Protein Acetylation Double-strand Break Repair Via Nonhomologous End Joining Hyperosmotic Response Cellular Response To Osmotic Stress Response To X-ray DNA Conformation Change Response To Salt Stress Chromosome Organization Cellular Response To Ionizing Radiation Telomere Maintenance DNA Duplex Unwinding DNA Geometric Change Positive Regulation Of Type I Interferon Production Response To Osmotic Stress Viral Process Mitotic Sister Chromatid Cohesion, Centromeric Regulation Of Type I Interferon Production Cellular Response To Radiation Response To Ionizing Radiation Double-strand Break Repair Peptidyl-amino Acid Modification DNA Recombination Hematopoietic Stem Cell Differentiation Positive Regulation Of Cytokine Production Mitotic Sister Chromatid Cohesion DNA Ligation Organelle Organization Positive Regulation Of Neurogenesis Response To Radiation Ribosomal Large Subunit Biogenesis Cellular Metabolic Process Positive Regulation Of Cell Development Regulation Of Cytokine Production V(D)J Recombination Sister Chromatid Cohesion DNA Repair Cellular Response To Fatty Acid Immune System Development
Tagcloud ?		annotation bub california cruz databases david deterioration downloaded exploring geo gse27567 h17 hub inheritance mendelian networks omim omnibus ranked santa topological visualization xpc xrcc4 ybx1 yy1 zfhx3 zfp36 zmat3
Tagcloud (Difference) ?		annotation bub california cruz databases david deterioration downloaded exploring geo gse27567 h17 hub inheritance mendelian networks omim omnibus ranked santa topological visualization xpc xrcc4 ybx1 yy1 zfhx3 zfp36 zmat3
Tagcloud (Intersection) ?