BAZ2A and DNMT3B

Number of citations of the paper that reports this interaction (PMID 16085498)
26

Data Source:
BioGRID (pull down)

		BAZ2A	DNMT3B
Gene Name		bromodomain adjacent to zinc finger domain, 2A	DNA (cytosine-5-)-methyltransferase 3 beta
Image
Gene Ontology Annotations	Cellular Component	Chromatin Silencing Complex Nucleolus RDNA Heterochromatin	Nucleus Nucleoplasm Nuclear Heterochromatin Cytoplasm Intracellular Membrane-bounded Organelle
	Molecular Function	DNA Binding RNA Binding Protein Binding Zinc Ion Binding Ligand-dependent Nuclear Receptor Binding Lysine-acetylated Histone Binding	Transcription Corepressor Activity DNA (cytosine-5-)-methyltransferase Activity Protein Binding DNA-methyltransferase Activity Unmethylated CpG Binding Metal Ion Binding DNA (cytosine-5-)-methyltransferase Activity, Acting On CpG Substrates
	Biological Process	Chromatin Silencing At RDNA DNA Methylation Chromatin Remodeling Transcription, DNA-templated Regulation Of Transcription, DNA-templated Gene Expression Histone Deacetylation Histone H4-K20 Methylation Regulation Of Gene Expression, Epigenetic Negative Regulation Of Gene Expression, Epigenetic Histone H3-K9 Methylation Heterochromatin Assembly Involved In Chromatin Silencing Histone H4 Deacetylation	Negative Regulation Of Transcription From RNA Polymerase II Promoter DNA Methylation Methylation-dependent Chromatin Silencing Regulation Of Gene Expression By Genetic Imprinting Response To Ionizing Radiation DNA Methylation On Cytosine Within A CG Sequence Gene Expression Positive Regulation Of Gene Expression Protein Complex Localization DNA Methylation On Cytosine Regulation Of Gene Expression, Epigenetic Response To Drug Positive Regulation Of Neuron Differentiation Negative Regulation Of Gene Expression, Epigenetic S-adenosylhomocysteine Metabolic Process S-adenosylmethioninamine Metabolic Process Positive Regulation Of Histone H3-K4 Methylation Negative Regulation Of Histone H3-K9 Methylation Cellular Response To Amino Acid Stimulus C-5 Methylation Of Cytosine
Pathways		NoRC negatively regulates rRNA expression Epigenetic regulation of gene expression Negative epigenetic regulation of rRNA expression	NoRC negatively regulates rRNA expression Epigenetic regulation of gene expression Negative epigenetic regulation of rRNA expression PRC2 methylates histones and DNA DNA methylation
Drugs
Diseases
GWAS		Mean platelet volume ( 22139419) Platelet counts ( 22139419)	Inflammatory bowel disease ( 23128233)
Protein-Protein Interactions		7 interactors: DNMT1 DNMT3B HDAC1 HIST1H4A KAT8 SMARCA5 TTF1	35 interactors: BAZ2A CBX1 CBX3 CBX5 CMTM6 DNMT1 DNMT3A DNMT3L DUSP23 EED EZH2 HDAC1 HDAC2 HELLS KIF4A MAP1LC3B MBD4 NCAPG NEDD8 NRIP1 PAM16 PCYT2 PLEKHJ1 RPS10 SMARCA5 SMC2 SPI1 SUMO1 SUV39H1 TDG TSC22D1 UBE2I UBE2W WARS ZBTB18
Entrez ID		11176	1789
HPRD ID		10417	04209
Ensembl ID		ENSG00000076108	ENSG00000088305
Uniprot IDs		F8VU39 J3KPG5 Q9UIF9	Q9UBC3
PDB IDs		4LZ2	3FLG 3QKJ
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Gene Expression, Epigenetic Regulation Of Gene Expression, Epigenetic Chromatin Modification Chromatin Organization Chromosome Organization Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process DNA Methylation On Cytosine Gene Silencing Negative Regulation Of Cellular Metabolic Process Chromatin Silencing Chromatin Remodeling C-5 Methylation Of Cytosine DNA Methylation ATP-dependent Chromatin Remodeling Organelle Organization Gene Expression DNA Modification Negative Regulation Of Histone H3-K9 Methylation Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of Histone H3-K4 Methylation Chromatin Silencing At RDNA Regulation Of RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Negative Regulation Of Histone Methylation Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Regulation Of Histone H3-K4 Methylation Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Gene Expression CENP-A Containing Nucleosome Assembly DNA-templated Transcription, Initiation Negative Regulation Of Transcription From RNA Polymerase II Promoter Nitrogen Compound Metabolic Process Histone Exchange DNA Replication-independent Nucleosome Assembly Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Histone Methylation Centromere Complex Assembly Regulation Of Histone Methylation DNA Metabolic Process Cellular Response To Amino Acid Stimulus Histone Modification	Negative Regulation Of Gene Expression, Epigenetic Regulation Of Gene Expression, Epigenetic Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Negative Regulation Of Cellular Metabolic Process DNA Modification Chromatin Modification Chromosome Organization Chromatin Silencing Chromatin Organization Gene Silencing Nucleobase-containing Compound Metabolic Process DNA Methylation Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Organelle Organization Cellular Nitrogen Compound Metabolic Process DNA Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Nitrogen Compound Metabolic Process Gene Expression Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process RNA Biosynthetic Process Cellular Metabolic Process Methylation Transcription, DNA-templated Histone H3-K9 Modification Chromatin Remodeling RNA Metabolic Process DNA Methylation On Cytosine Regulation Of Transcription From RNA Polymerase II Promoter Chromatin Silencing At RDNA Histone Modification Peptidyl-lysine Modification Histone H4 Deacetylation Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Rhythmic Process DNA Packaging Regulation Of Gene Expression By Genetic Imprinting Hypermethylation Of CpG Island C-5 Methylation Of Cytosine
Tagcloud ?		bc bladder characterizing fgfr3 formulation lowered messenger micrornas mir mirna mtor oncogenes oncogenesis oncomir ploidy promoted promoting qrt representative respective rnas rt4 smarca5 supposed t24 thap2 today transfection urothelial	cpg cues de dense dnmt1 dnmts enhancers ensure ensures establishment excluded guide lethal localize methylated methylation methylome methyltransferase methyltransferases novo nucleosomes observe preferential promoters pwwp reflects setd2 transcribed
Tagcloud (Difference) ?		bc bladder characterizing fgfr3 formulation lowered messenger micrornas mir mirna mtor oncogenes oncogenesis oncomir ploidy promoted promoting qrt representative respective rnas rt4 smarca5 supposed t24 thap2 today transfection urothelial	cpg cues de dense dnmt1 dnmts enhancers ensure ensures establishment excluded guide lethal localize methylated methylation methylome methyltransferase methyltransferases novo nucleosomes observe preferential promoters pwwp reflects setd2 transcribed
Tagcloud (Intersection) ?