BAZ2A

Description		bromodomain adjacent to zinc finger domain 2A
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Chromatin Silencing Complex Nucleolus Cytosol Nuclear Speck RDNA Heterochromatin NoRC Complex
	Molecular Function	RNA Polymerase I Core Promoter Sequence-specific DNA Binding DNA Binding RNA Binding Protein Binding Zinc Ion Binding Nuclear Receptor Binding Histone Binding Metal Ion Binding Histone H4K16ac Reader Activity
	Biological Process	RDNA Heterochromatin Formation RNA Polymerase I Preinitiation Complex Assembly Chromatin Organization Chromatin Remodeling DNA Methylation-dependent Constitutive Heterochromatin Formation DNA-templated Transcription Regulation Of DNA-templated Transcription Negative Regulation Of Transcription By RNA Polymerase I Heterochromatin Formation
Pathways		NoRC negatively regulates rRNA expression
Drugs
Diseases
GWAS		Alanine aminotransferase levels ( 33547301) Mean platelet volume ( 22139419 27863252 32888494) Platelet count ( 22139419 32888494) Platelet distribution width ( 32888494)
Interacting Genes		8 interacting genes: ADRB2 DNMT1 DNMT3B H4C1 HDAC1 KAT8 SMARCA5 TTF1
Entrez ID		11176
HPRD ID		10417
Ensembl ID		ENSG00000076108
Uniprot IDs		F8VU39 J3KPG5 Q9UIF9
PDB IDs		4LZ2 4Q6F 4QBM 4QF2 5AGQ 5MGJ 5MGK 5MGL 5MGM 5OR8 5T8R 6FAP 6FG6 6FGF 6FGG 6FGH 6FGI 6FGL 6FGV 6FGW 6FHU 6FI0 6FKP 7B7B 7B7G 7B7I 7B82 7BC2 7BL8 7BL9 7BLA 7BLB 7BLC 7BLD 7FHJ 7MWH 7MWI 7MWL 7QVT 7QVU 7QVV 7QWF 7QWU 7QWY 7QX2 7QX9 7QXL 7QYE 7QYO 7QYT 7QYU 7QYV 7QYW 7QZ0 7QZ4 7QZB 7QZC 7QZI 7QZT 7R01 7R0B
Enriched GO Terms of Interacting Partners?		Chromatin Remodeling Negative Regulation Of Gene Expression, Epigenetic DNA-methyltransferase Activity Heterochromatin Formation DNA Methylation-dependent Constitutive Heterochromatin Formation Chromatin Organization DNA (cytosine-5-)-methyltransferase Activity Constitutive Heterochromatin Formation Promoter-specific Chromatin Binding Epigenetic Regulation Of Gene Expression Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Developmental Process Chromatin Binding DNA Binding Pericentric Heterochromatin Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Cell Differentiation Negative Regulation Of RNA Metabolic Process Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Macromolecule Biosynthetic Process Nucleoplasm Negative Regulation Of Macromolecule Metabolic Process Heterochromatin Positive Regulation Of Biosynthetic Process Nucleus Negative Regulation Of Metabolic Process Nucleobase-containing Compound Biosynthetic Process Regulation Of Systemic Arterial Blood Pressure By Norepinephrine-epinephrine Positive Regulation Of Mini Excitatory Postsynaptic Potential Negative Regulation Of Muscle Cell Differentiation DNA (cytosine-5-)-methyltransferase Activity, Acting On CpG Substrates DNA-templated Transcription Initiation DNA-templated Transcription Enzyme Binding Positive Regulation Of Macromolecule Metabolic Process Regulation Of DNA-templated Transcription Regulation Of Primary Metabolic Process Regulation Of RNA Biosynthetic Process Beta2-adrenergic Receptor Activity Negative Regulation Of Vascular Associated Smooth Muscle Cell Differentiation Involved In Phenotypic Switching Positive Regulation Of Smooth Muscle Cell Proliferation Chromosomal DNA Methylation Maintenance Following DNA Replication Krueppel-associated Box Domain Binding WICH Complex Negative Regulation Of Mitotic Chromosome Condensation ISWI-type Complex NoRC Complex Histone Octamer Slider Activity
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