PTP4A3 and FNTA

Number of citations of the paper that reports this interaction (PMID 10747914)
24

Data Source:
HPRD (in vitro)

		PTP4A3	FNTA
Gene Name		protein tyrosine phosphatase type IVA, member 3	farnesyltransferase, CAAX box, alpha
Image
Gene Ontology Annotations	Cellular Component	Early Endosome Plasma Membrane	Cytoplasm Cytosol Microtubule Associated Complex CAAX-protein Geranylgeranyltransferase Complex Protein Farnesyltransferase Complex
	Molecular Function	Prenylated Protein Tyrosine Phosphatase Activity	Protein Farnesyltransferase Activity Protein Geranylgeranyltransferase Activity CAAX-protein Geranylgeranyltransferase Activity Rab Geranylgeranyltransferase Activity Protein Binding Microtubule Binding Acetylcholine Receptor Regulator Activity Receptor Tyrosine Kinase Binding Alpha-tubulin Binding
	Biological Process	Peptidyl-tyrosine Dephosphorylation Endothelial Cell Migration	Apoptotic Process Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Transforming Growth Factor Beta Receptor Signaling Pathway Phototransduction, Visible Light Regulation Of Receptor Activity Rhodopsin Mediated Signaling Pathway Protein Farnesylation Protein Geranylgeranylation Regulation Of Rhodopsin Mediated Signaling Pathway Neurotransmitter Receptor Metabolic Process Positive Regulation Of Tubulin Deacetylation Positive Regulation Of Deacetylase Activity
Pathways			Inactivation, recovery and regulation of the phototransduction cascade Apoptotic cleavage of cellular proteins Visual phototransduction The phototransduction cascade Programmed Cell Death Apoptotic execution phase Diseases associated with visual transduction
Drugs
Diseases
GWAS
Protein-Protein Interactions		2 interactors: FNTA FNTB	17 interactors: ACVR1 CENPF FNTB GBP1 HDAC6 HRAS INHBB KRAS PTP4A3 RHOB RPL13A SAFB2 STAT2 TGFB1 TGFBR1 TGM2 VAV2
Entrez ID		11156	2339
HPRD ID		05922	00607
Ensembl ID			ENSG00000168522
Uniprot IDs		O75365	P49354
PDB IDs		1R6H 1V3A	1JCQ 1LD7 1LD8 1MZC 1S63 1SA4 1TN6 2F0Y 2H6F 2H6G 2H6H 2H6I 2IEJ 3E37
Enriched GO Terms of Interacting Partners?		Protein Farnesylation Protein Prenylation Regulation Of Rhodopsin Mediated Signaling Pathway Rhodopsin Mediated Signaling Pathway Phototransduction, Visible Light Detection Of Visible Light Cellular Response To Light Stimulus Phototransduction Detection Of Light Stimulus Cellular Response To Radiation Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Detection Of Abiotic Stimulus Positive Regulation Of Tubulin Deacetylation Response To Light Stimulus Response To Radiation Regulation Of Tubulin Deacetylation Positive Regulation Of Deacetylase Activity Detection Of Stimulus Protein Geranylgeranylation Neurotransmitter Receptor Metabolic Process Positive Regulation Of Nitric-oxide Synthase Biosynthetic Process Positive Regulation Of Protein Deacetylation Response To Abiotic Stimulus G-protein Coupled Receptor Signaling Pathway Regulation Of Protein Deacetylation Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Positive Regulation Of Fibroblast Proliferation Response To External Stimulus Execution Phase Of Apoptosis Receptor Metabolic Process Regulation Of Fibroblast Proliferation Regulation Of Receptor Activity Response To Organic Substance Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Signal Transduction Cellular Response To Transforming Growth Factor Beta Stimulus Response To Transforming Growth Factor Beta Regulation Of Signaling Cell Surface Receptor Signaling Pathway Cellular Protein Modification Process Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Positive Regulation Of Metabolic Process Positive Regulation Of Cell Cycle	Cellular Response To Organic Substance Response To Organic Substance Regulation Of Cell Death Response To Stress Regulation Of Signal Transduction Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation Regulation Of Pathway-restricted SMAD Protein Phosphorylation Regulation Of Signaling Response To External Stimulus Defense Response Positive Regulation Of Programmed Cell Death Response To Growth Factor Pathway-restricted SMAD Protein Phosphorylation Wound Healing Positive Regulation Of Cell Death Regulation Of Apoptotic Process Response To Wounding Morphogenesis Of A Branching Epithelium Morphogenesis Of A Branching Structure Innate Immune Response Activin Receptor Signaling Pathway Locomotion Cell Migration Positive Regulation Of Signal Transduction Signal Transduction By Phosphorylation Positive Regulation Of Phosphorylation Cell Surface Receptor Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Cell Motility Cellular Response To Growth Factor Stimulus Positive Regulation Of Apoptotic Process Regulation Of Cellular Protein Metabolic Process Movement Of Cell Or Subcellular Component Positive Regulation Of Rac Protein Signal Transduction Cellular Response To Stimulus Response To Abiotic Stimulus Regulation Of Protein Metabolic Process Cell Morphogenesis Involved In Differentiation Positive Regulation Of Protein Phosphorylation Response To Stimulus Cell Communication Blood Coagulation Tube Morphogenesis Hemostasis Branching Morphogenesis Of An Epithelial Tube Regulation Of Intracellular Signal Transduction Response To Radiation Negative Regulation Of Cell Cycle Activation Of MAPKK Activity Cell Development
Tagcloud ?		aberrations ann arbor barr bcl2 cd10 cd320 cd45 cd56 clinicopathologic cutaneous dnmt3b ebv epstein extranodal hodgkin ic immunocompetent immunodeficiency immunologic pbl pbls plasmablastic positivity recipients summarized testis unpublished	21q11 8p11 aberration cbl comprehensively constitutional ct8m gained golga7 harbouring ikbkb jmml juvenile leukaemia leukaemogenesis malignancies mir486 monosomy mosaic mosaicisms myelomonocytic myst3 nf1 nras ptpn11 smallest submicroscopic trisomy ube2v2
Tagcloud (Difference) ?		aberrations ann arbor barr bcl2 cd10 cd320 cd45 cd56 clinicopathologic cutaneous dnmt3b ebv epstein extranodal hodgkin ic immunocompetent immunodeficiency immunologic pbl pbls plasmablastic positivity recipients summarized testis unpublished	21q11 8p11 aberration cbl comprehensively constitutional ct8m gained golga7 harbouring ikbkb jmml juvenile leukaemia leukaemogenesis malignancies mir486 monosomy mosaic mosaicisms myelomonocytic myst3 nf1 nras ptpn11 smallest submicroscopic trisomy ube2v2
Tagcloud (Intersection) ?