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GLMN and MET
Number of citations of the paper that reports this interaction (PMID
11571281
)
6
Data Source:
HPRD
(in vivo, two hybrid)
GLMN
MET
Gene Name
glomulin, FKBP associated protein
MET proto-oncogene, receptor tyrosine kinase
Image
Gene Ontology Annotations
Cellular Component
Intracellular
Cullin-RING Ubiquitin Ligase Complex
Cul2-RING Ubiquitin Ligase Complex
Cul3-RING Ubiquitin Ligase Complex
Cul4A-RING E3 Ubiquitin Ligase Complex
Extracellular Region
Plasma Membrane
Integral Component Of Plasma Membrane
Basal Plasma Membrane
Cell Surface
Integral Component Of Membrane
Molecular Function
Hepatocyte Growth Factor Receptor Binding
Protein Binding
Ubiquitin Protein Ligase Binding
Ubiquitin-protein Transferase Inhibitor Activity
Protein Tyrosine Kinase Activity
Hepatocyte Growth Factor-activated Receptor Activity
Protein Binding
ATP Binding
Protein Phosphatase Binding
Biological Process
Vasculogenesis
Neural Tube Closure
Negative Regulation Of Protein Ubiquitination
Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Regulation Of Gene Expression, Epigenetic
Negative Regulation Of T Cell Proliferation
Positive Regulation Of Phosphorylation
Muscle Cell Differentiation
Positive Regulation Of Interleukin-2 Biosynthetic Process
Positive Regulation Of Cytokine Secretion
Activation Of MAPK Activity
Endothelial Cell Morphogenesis
Liver Development
Placenta Development
Signal Transduction
Cell Surface Receptor Signaling Pathway
Axon Guidance
Brain Development
Skeletal Muscle Tissue Development
Cell Proliferation
Positive Regulation Of Glucose Transport
Muscle Cell Migration
Myotube Differentiation
Peptidyl-tyrosine Phosphorylation
Adult Behavior
Glucose Homeostasis
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Protein Autophosphorylation
Hepatocyte Growth Factor Receptor Signaling Pathway
Branching Morphogenesis Of An Epithelial Tube
Positive Chemotaxis
Myoblast Proliferation
Regulation Of Branching Involved In Salivary Gland Morphogenesis By Mesenchymal-epithelial Signaling
Semaphorin-plexin Signaling Pathway
Negative Regulation Of Hydrogen Peroxide-mediated Programmed Cell Death
Positive Regulation Of Endothelial Cell Chemotaxis
Pathways
Axon guidance
Semaphorin interactions
Sema4D mediated inhibition of cell attachment and migration
Sema4D in semaphorin signaling
Drugs
K-252a
1-(4-fluorophenyl)-N-[3-fluoro-4-(1H-pyrrolo[2,3-b]pyridin-4-yloxy)phenyl]-2-oxo-1,2-dihydropyridine-3-carboxamide
N-({4-[(2-aminopyridin-4-yl)oxy]-3-fluorophenyl}carbamoyl)-2-(4-fluorophenyl)acetamide
2-(4-fluorophenyl)-N-{[3-fluoro-4-(1H-pyrrolo[2,3-b]pyridin-4-yloxy)phenyl]carbamoyl}acetamide
N-(3-chlorophenyl)-N-methyl-2-oxo-3-[(3,4,5-trimethyl-1H-pyrrol-2-yl)methyl]-2H-indole-5-sulfonamide
3-[3-(4-methylpiperazin-1-yl)-7-(trifluoromethyl)quinoxalin-5-yl]phenol
6-{[6-(1-methyl-1H-pyrazol-4-yl)[1,2,4]triazolo[4,3-b]pyridazin-3-yl]sulfanyl}quinoline
3-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-(1-piperidin-4-yl-1H-pyrazol-4-yl)pyridin-2-amine
1-[(2-NITROPHENYL)SULFONYL]-1H-PYRROLO[3,2-B]PYRIDINE-6-CARBOXAMIDE
Cabozantinib
Diseases
GWAS
Multiple sclerosis (severity) (
19010793
)
Protein-Protein Interactions
9 interactors:
CUL1
FBXW7
FKBP1A
FKBP4
MET
NSFL1C
RBX1
RNF7
SKP1
37 interactors:
BAG1
CASP3
CBL
CNR1
CTNNB1
CTTN
DAPK3
DCN
DNAJA3
EGFR
FAS
GAB1
GLMN
GRB2
HGF
HGS
INPP5D
INPPL1
ITGB4
MUC20
PCBD2
PIK3R1
PLCG1
PLXNB1
PTPN11
PTPRB
PTPRJ
RANBP10
RANBP9
SHC1
SMC1A
SNAPIN
SNX2
SPSB1
SRC
STAT3
VAV1
Entrez ID
11146
4233
HPRD ID
03451
01280
Ensembl ID
ENSG00000174842
ENSG00000105976
Uniprot IDs
B4DJ85
Q92990
B4DLF5
P08581
PDB IDs
4F52
1FYR
1R0P
1R1W
1SHY
1SSL
1UX3
2G15
2RFN
2RFS
2UZX
2UZY
2WD1
2WGJ
2WKM
3A4P
3BUX
3C1X
3CCN
3CD8
3CE3
3CTH
3CTJ
3DKC
3DKF
3DKG
3EFJ
3EFK
3F66
3F82
3I5N
3L8V
3LQ8
3Q6U
3Q6W
3QTI
3R7O
3RHK
3U6H
3U6I
3VW8
3ZXZ
3ZZE
4AOI
4AP7
4DEG
4DEH
4DEI
4EEV
4GG5
4GG7
4K3J
Enriched GO Terms of Interacting Partners
?
SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Proteasomal Protein Catabolic Process
Positive Regulation Of Protein Ubiquitination
Notch Signaling Pathway
Cellular Protein Metabolic Process
Protein Monoubiquitination
Ubiquitin-dependent Protein Catabolic Process
Modification-dependent Protein Catabolic Process
Regulation Of Protein Ubiquitination
Proteolysis Involved In Cellular Protein Catabolic Process
Cellular Protein Catabolic Process
Cellular Protein Modification Process
Protein Ubiquitination
Protein Catabolic Process
Protein Modification By Small Protein Conjugation
Protein Metabolic Process
Positive Regulation Of Ubiquitin-protein Transferase Activity
Positive Regulation Of Ligase Activity
Cell Communication
Positive Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Regulation Of Ubiquitin-protein Transferase Activity
Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Protein Neddylation
Cellular Macromolecule Catabolic Process
Positive Regulation Of Protein Modification Process
Cellular Response To Stimulus
Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process
Positive Regulation Of Cellular Protein Catabolic Process
Positive Regulation Of Cellular Protein Metabolic Process
Viral Process
Positive Regulation Of Transferase Activity
Positive Regulation Of Protein Metabolic Process
Signal Transduction
Positive Regulation Of Protein Catabolic Process
Regulation Of Catalytic Activity
Response To Stimulus
Signaling
Cellular Response To Stress
Proteolysis
Positive Regulation Of Proteolysis
Regulation Of Cellular Response To Oxidative Stress
Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition
Catabolic Process
Chaperone-mediated Protein Folding
Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle
Cell Surface Receptor Signaling Pathway
Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process
Regulation Of Protein Catabolic Process
Regulation Of Cellular Protein Metabolic Process
Epidermal Growth Factor Receptor Signaling Pathway
ERBB Signaling Pathway
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Neurotrophin TRK Receptor Signaling Pathway
Neurotrophin Signaling Pathway
Fibroblast Growth Factor Receptor Signaling Pathway
Cellular Response To Growth Factor Stimulus
Enzyme Linked Receptor Protein Signaling Pathway
Anatomical Structure Development
Regulation Of Cell Activation
Response To Growth Factor
Developmental Process
System Development
Cellular Response To Fibroblast Growth Factor Stimulus
Regulation Of Signaling
Response To Fibroblast Growth Factor
Regulation Of Signal Transduction
Multicellular Organismal Development
Positive Regulation Of Signal Transduction
Regulation Of Immune System Process
Signaling
Cell Surface Receptor Signaling Pathway
Signal Transduction
Cell Communication
Regulation Of Lymphocyte Activation
Locomotion
Movement Of Cell Or Subcellular Component
Response To Wounding
Regulation Of Phosphorylation
Cell Differentiation
Cell Motility
Anatomical Structure Morphogenesis
Neuron Differentiation
Intracellular Signal Transduction
Response To Organic Substance
Neurogenesis
Regulation Of Cell Adhesion
Regulation Of Phosphorus Metabolic Process
Cell Migration
Regulation Of Intracellular Signal Transduction
Immune Response-regulating Cell Surface Receptor Signaling Pathway
Positive Regulation Of Metabolic Process
Fc Receptor Signaling Pathway
Regulation Of Cell Death
Generation Of Neurons
Regulation Of T Cell Activation
Regulation Of Protein Metabolic Process
Blood Coagulation
Hemostasis
Response To Stimulus
Tagcloud
?
basophil
basophils
c5a
ccr2
ccr3
chains
chemoattractant
chemotactic
continuous
continuously
cxcr1
cxcr2
eotaxin
express
fmlp
formyl
granulocyte
hardly
leu
leukotrienes
lt
ltc4
macrophage
mcp
mcp1
mediate
migratory
phe
unrelated
weakly
Tagcloud (Difference)
?
basophil
basophils
c5a
ccr2
ccr3
chains
chemoattractant
chemotactic
continuous
continuously
cxcr1
cxcr2
eotaxin
express
fmlp
formyl
granulocyte
hardly
leu
leukotrienes
lt
ltc4
macrophage
mcp
mcp1
mediate
migratory
phe
unrelated
weakly
Tagcloud (Intersection)
?