GLMN and PPDPF

Number of citations of the paper that reports this interaction (PubMedID 34975328)
48

Data Source:
BioGRID (two hybrid)

		GLMN	PPDPF
Description		glomulin, FKBP associated protein	pancreatic progenitor cell differentiation and proliferation factor
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cullin-RING Ubiquitin Ligase Complex Cul2-RING Ubiquitin Ligase Complex Cul3-RING Ubiquitin Ligase Complex Cul4A-RING E3 Ubiquitin Ligase Complex	Mitochondrion
	Molecular Function	Signaling Receptor Binding Hepatocyte Growth Factor Receptor Binding Protein Binding Ubiquitin Protein Ligase Binding Ubiquitin-protein Transferase Inhibitor Activity
	Biological Process	Vasculogenesis Positive Regulation Of Cytokine Production Neural Tube Closure Cell Surface Receptor Signaling Pathway Negative Regulation Of Cell Population Proliferation Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Interleukin-2 Production Epigenetic Regulation Of Gene Expression Negative Regulation Of T Cell Proliferation Positive Regulation Of Phosphorylation Muscle Cell Differentiation Circulatory System Development	Liver Development Cell Differentiation TOR Signaling TORC1 Signaling
Pathways		Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases		Venous malformations, including: Sporadic venous malformation; Cutaneomucosal venous malformation; Glomuvenous malformation
GWAS		Granulocyte percentage of myeloid white cells ( 27863252) Lymphocyte percentage of white cells ( 27863252) Monocyte count ( 27863252) Monocyte percentage of white cells ( 27863252) Myeloid white cell count ( 27863252)	Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 31043756) Bipolar I disorder ( 31043756) Estimated glomerular filtration rate ( 31152163) Prostate cancer ( 23535732) Serum metabolite levels ( 33031748)
Interacting Genes		17 interacting genes: BIRC2 BIRC3 EFS FBXW7 FKBP1A FKBP4 HSPB1 MET NSFL1C OGT PEX5 PPDPF PRDM16 RBX1 RNF7 SKP1 SNAI1	11 interacting genes: BABAM2 CTSC DDB1 DNAJB1 GLMN MT2A PLSCR1 PRMT1 RIPK1 RPTOR TRIP6
Entrez ID		11146	79144
HPRD ID		03451	12750
Ensembl ID		ENSG00000174842	ENSG00000125534
Uniprot IDs		B4DJ85 Q92990	Q9H3Y8
PDB IDs		4F52
Enriched GO Terms of Interacting Partners?		Regulation Of Programmed Cell Death Regulation Of Protein Ubiquitination Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Regulation Of Necroptotic Process Regulation Of Post-translational Protein Modification Intracellular Signal Transduction Ubiquitin Binding Positive Regulation Of Protein Ubiquitination Negative Regulation Of Signal Transduction Negative Regulation Of Cell Communication Negative Regulation Of Signaling Cullin Family Protein Binding SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Cul7-RING Ubiquitin Ligase Complex NEDD8 Ligase Activity Regulation Of Programmed Necrotic Cell Death Positive Regulation Of Post-translational Protein Modification Negative Regulation Of Protein-containing Complex Assembly NEDD8 Transferase Activity Modification-dependent Protein Catabolic Process Regulation Of Canonical NF-kappaB Signal Transduction Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination Protein Catabolic Process Cytosol Protein Monoubiquitination Regulation Of Signal Transduction Regulation Of Protein Modification Process SCF Ubiquitin Ligase Complex Negative Regulation Of Proteasomal Protein Catabolic Process Proteolysis Involved In Protein Catabolic Process Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process TORC1 Signaling Protein Modification By Small Protein Conjugation Negative Regulation Of Cellular Component Organization Regulation Of Intracellular Signal Transduction FK506 Binding Regulation Of Protein-containing Complex Assembly Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Protein-containing Complex Heterochromatin Organization Positive Regulation Of Canonical NF-kappaB Signal Transduction Negative Regulation Of Proteolysis Involved In Protein Catabolic Process Regulation Of Cell Communication Cytoplasm Regulation Of Signaling Proteolysis Epithelial To Mesenchymal Transition	Positive Regulation Of Protein Metabolic Process Cell Death Positive Regulation Of Macromolecule Metabolic Process Apoptotic Process Cytoplasm Regulation Of Signal Transduction Programmed Cell Death Regulation Of Immune System Process Regulation Of Protein Metabolic Process Cul4A-RING E3 Ubiquitin Ligase Complex Cellular Response To Stress Positive Regulation Of Myeloid Cell Differentiation Positive Regulation Of Metabolic Process Regulation Of Cell Communication Regulation Of Signaling Regulation Of Myeloid Cell Differentiation Regulation Of Primary Metabolic Process Negative Regulation Of Translational Initiation Positive Regulation Of Gene Expression Protein Localization To Lysosome GATOR1 Complex Binding Regulation Of Intracellular Signal Transduction Positive Regulation Of Myeloid Leukocyte Differentiation TORC1 Signaling Positive Regulation Of Non-canonical NF-kappaB Signal Transduction Positive Regulation Of TORC1 Signaling Regulation Of Cell Cycle Process Regulation Of Macromolecule Metabolic Process Positive Regulation Of Phosphate Metabolic Process Regulation Of Viral Genome Replication Protein-containing Complex Binding DNA Damage Response Response To Stress Regulation Of Mitotic Cell Cycle Phase Transition TOR Signaling Cellular Response To Amino Acid Stimulus Lead Ion Binding Ripoptosome Assembly Ripoptosome Assembly Involved In Necroptotic Process Hepatocyte Growth Factor Receptor Binding Positive Regulation Of TOR Signaling Chromatin Organization Protein Localization To Vacuole Protein-folding Chaperone Binding Regulation Of Metabolic Process Regulation Of TORC1 Signaling Positive Regulation Of Protein Folding Phosphatidylserine Biosynthetic Process Mercury Ion Binding Phosphatidylserine Exposure On Apoptotic Cell Surface
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