GLMN and NSFL1C

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
HPRD (two hybrid)

		GLMN	NSFL1C
Description		glomulin, FKBP associated protein	NSFL1 cofactor
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GO Annotations	Cellular Component	Cytoplasm Cullin-RING Ubiquitin Ligase Complex Cul2-RING Ubiquitin Ligase Complex Cul3-RING Ubiquitin Ligase Complex Cul4A-RING E3 Ubiquitin Ligase Complex	Nucleus Chromosome Cytoplasm Golgi Apparatus Golgi Stack Centrosome Cytosol Cytoskeleton VCP-NSFL1C Complex
	Molecular Function	Signaling Receptor Binding Hepatocyte Growth Factor Receptor Binding Protein Binding Ubiquitin Protein Ligase Binding Ubiquitin-protein Transferase Inhibitor Activity	Protein Binding Lipid Binding Ubiquitin Binding
	Biological Process	Vasculogenesis Positive Regulation Of Cytokine Production Neural Tube Closure Cell Surface Receptor Signaling Pathway Negative Regulation Of Cell Population Proliferation Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Interleukin-2 Production Epigenetic Regulation Of Gene Expression Negative Regulation Of T Cell Proliferation Positive Regulation Of Phosphorylation Muscle Cell Differentiation Circulatory System Development	Autophagosome Assembly Establishment Of Mitotic Spindle Orientation Ubiquitin-dependent Protein Catabolic Process Golgi Organization Nuclear Membrane Reassembly Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Mitotic Centrosome Separation Membrane Fusion Negative Regulation Of Protein Localization To Centrosome
Pathways		Antigen processing: Ubiquitination & Proteasome degradation	RHOH GTPase cycle
Drugs
Diseases		Venous malformations, including: Sporadic venous malformation; Cutaneomucosal venous malformation; Glomuvenous malformation
GWAS		Granulocyte percentage of myeloid white cells ( 27863252) Lymphocyte percentage of white cells ( 27863252) Monocyte count ( 27863252) Monocyte percentage of white cells ( 27863252) Myeloid white cell count ( 27863252)
Interacting Genes		17 interacting genes: BIRC2 BIRC3 EFS FBXW7 FKBP1A FKBP4 HSPB1 MET NSFL1C OGT PEX5 PPDPF PRDM16 RBX1 RNF7 SKP1 SNAI1	19 interacting genes: ANP32A CDK1 CEBPA DBI FAM32A GLMN GSK3B LIPE NEDD8 NGLY1 PBK PHAX PRKACA RPL22 SRP14 STX5 TARDBP UBC VCP
Entrez ID		11146	55968
HPRD ID		03451	09425
Ensembl ID		ENSG00000174842	ENSG00000088833
Uniprot IDs		B4DJ85 Q92990	Q53FE8 Q9UNZ2
PDB IDs		4F52	1SS6 8HRZ
Enriched GO Terms of Interacting Partners?		Regulation Of Programmed Cell Death Regulation Of Protein Ubiquitination Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Regulation Of Necroptotic Process Regulation Of Post-translational Protein Modification Intracellular Signal Transduction Ubiquitin Binding Positive Regulation Of Protein Ubiquitination Negative Regulation Of Signal Transduction Negative Regulation Of Cell Communication Negative Regulation Of Signaling Cullin Family Protein Binding SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Cul7-RING Ubiquitin Ligase Complex NEDD8 Ligase Activity Regulation Of Programmed Necrotic Cell Death Positive Regulation Of Post-translational Protein Modification Negative Regulation Of Protein-containing Complex Assembly NEDD8 Transferase Activity Modification-dependent Protein Catabolic Process Regulation Of Canonical NF-kappaB Signal Transduction Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination Protein Catabolic Process Cytosol Protein Monoubiquitination Regulation Of Signal Transduction Regulation Of Protein Modification Process SCF Ubiquitin Ligase Complex Negative Regulation Of Proteasomal Protein Catabolic Process Proteolysis Involved In Protein Catabolic Process Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process TORC1 Signaling Protein Modification By Small Protein Conjugation Negative Regulation Of Cellular Component Organization Regulation Of Intracellular Signal Transduction FK506 Binding Regulation Of Protein-containing Complex Assembly Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Protein-containing Complex Heterochromatin Organization Positive Regulation Of Canonical NF-kappaB Signal Transduction Negative Regulation Of Proteolysis Involved In Protein Catabolic Process Regulation Of Cell Communication Cytoplasm Regulation Of Signaling Proteolysis Epithelial To Mesenchymal Transition	Regulation Of Protein Catabolic Process Regulation Of Proteasomal Protein Catabolic Process Regulation Of Proteolysis Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Nucleocytoplasmic Transport Ubiquitin Protein Ligase Binding Regulation Of Ubiquitin-dependent Protein Catabolic Process Regulation Of Protein Metabolic Process Positive Regulation Of Intracellular Protein Transport Regulation Of Nucleocytoplasmic Transport Regulation Of Generation Of Precursor Metabolites And Energy Positive Regulation Of Intracellular Transport Golgi Disassembly Regulation Of Intracellular Protein Transport RNA Binding Modification-dependent Protein Catabolic Process Negative Regulation Of Catabolic Process Positive Regulation Of Protein Catabolic Process Proteolysis Involved In Protein Catabolic Process Organelle Disassembly Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Macromolecule Catabolic Process Protein Metabolic Process Protein Tag Activity Positive Regulation Of Protein Transport Regulation Of Intracellular Transport Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Protein Export From Nucleus Regulation Of Circadian Rhythm Positive Regulation Of Proteasomal Protein Catabolic Process Intracellular Signaling Cassette Positive Regulation Of Catabolic Process Ubiquitin-dependent Protein Catabolic Process Glutamatergic Synapse Positive Regulation Of Establishment Of Protein Localization Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Protein Catabolic Process Protein Serine Kinase Activity Protein Phosphorylation Macromolecule Metabolic Process Nucleus Regulation Of Osteoblast Differentiation Regulation Of Primary Metabolic Process Regulation Of Protein Localization To Nucleus Negative Regulation Of Smoothened Signaling Pathway Regulation Of Protein Export From Nucleus Phosphorylation Catabolic Process Positive Regulation Of Protein Import Into Nucleus Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
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