CHGA and PFDN1

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		CHGA	PFDN1
Gene Name		chromogranin A (parathyroid secretory protein 1)	prefoldin subunit 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Secretory Granule Transport Vesicle Membrane Perinuclear Region Of Cytoplasm	Prefoldin Complex
	Molecular Function		Sequence-specific DNA Binding Transcription Factor Activity Unfolded Protein Binding
	Biological Process	Regulation Of Blood Pressure	Regulation Of Transcription, DNA-templated Protein Folding Cell Cycle Telencephalon Development Cerebellum Development Actin Cytoskeleton Organization B Cell Activation Cellular Protein Metabolic Process 'de Novo' Posttranslational Protein Folding
Pathways			Protein folding Prefoldin mediated transfer of substrate to CCT/TriC Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding Chaperonin-mediated protein folding
Drugs
Diseases
GWAS
Protein-Protein Interactions		6 interactors: CDC37 NEK2 PFDN1 PLG SCG3 UBC	54 interactors: ACTA1 ACTB ALB ASNA1 BRK1 CCDC85A CHGA DCTN1 DEFA1 DGCR14 EDRF1 EIF3C EIF4A2 EOMES EXT2 EZH2 FAM20C GIT1 GPRASP1 HAP1 HIP1 HMGXB3 HOXD8 IFT140 IMMT INPP5K JADE1 KIAA0408 KIAA1377 LRIF1 MED31 NDC80 NR2F1 PDE4DIP PDHB PFDN2 PLXNB2 PRKD2 PSME1 PTN RMI1 RPLP1 RPS28 SEC31A SKP2 SNX5 SPTBN4 SUMO3 SYNDIG1 TERT TTC38 TUBA1A YEATS4 ZNF235
Entrez ID		1113	5201
HPRD ID		07170	05357
Ensembl ID		ENSG00000100604	ENSG00000113068
Uniprot IDs		G5E968 P10645 Q86T07	O60925
PDB IDs		1LV4
Enriched GO Terms of Interacting Partners?		Platelet Degranulation Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Negative Regulation Of Centriole-centriole Cohesion Cellular Protein Catabolic Process Protein Catabolic Process G2/M Transition Of Mitotic Cell Cycle Cell Activation Establishment Of Localization In Cell Mononuclear Cell Migration Regulation Of Centriole-centriole Cohesion Cellular Macromolecule Catabolic Process Negative Regulation Of Cell-cell Adhesion Mediated By Cadherin Positive Regulation Of Fibrinolysis Platelet Activation Cellular Protein Metabolic Process Regulation Of Cell Cycle Regulation Of Mitotic Centrosome Separation Cellular Localization Regulation Of Innate Immune Response Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Protein Folding Negative Regulation Of Fibrinolysis Viral Protein Processing Exocytosis Cell Cycle Protein Metabolic Process Regulation Of Fibrinolysis Centrosome Separation Regulation Of Mitotic Cell Cycle Blood Coagulation Proteolysis Hemostasis Mitotic Spindle Assembly Trophoblast Giant Cell Differentiation Regulation Of Interferon-gamma-mediated Signaling Pathway Regulation Of Response To Interferon-gamma Notch Receptor Processing Regulation Of Attachment Of Spindle Microtubules To Kinetochore Virion Assembly Regulation Of Cell Cycle Process Ubiquitin-dependent Protein Catabolic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Secretion By Cell In Utero Embryonic Development Modification-dependent Protein Catabolic Process Nucleotide-binding Oligomerization Domain Containing Signaling Pathway	Organelle Organization Cellular Localization Cellular Macromolecule Biosynthetic Process Cellular Component Assembly Macromolecule Biosynthetic Process Gene Expression Membrane Organization RNA Biosynthetic Process Cellular Protein Localization Establishment Of Protein Localization To Membrane Protein Localization Developmental Process Cerebral Cortex Regionalization Mitotic Cell Cycle Biosynthetic Process Cellular Process Cytoskeleton-dependent Intracellular Transport Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G1/S Phase Transition Cellular Metabolic Process Establishment Of Localization In Cell Anatomical Structure Development RNA Metabolic Process Organelle Localization 'de Novo' Posttranslational Protein Folding Intracellular Transport Cell Cycle Process 'de Novo' Protein Folding Regulation Of Metabolic Process Telencephalon Regionalization Regulation Of Protein Metabolic Process Mitotic Cell Cycle Process Regulation Of Cellular Component Organization Regulation Of Cellular Protein Metabolic Process Protein Localization To Organelle Positive Regulation Of Cellular Metabolic Process Protein Localization To Membrane Vesicle Localization Regulation Of Cilium Assembly Multicellular Organismal Development Regulation Of Cellular Process Regulation Of Mitotic Cell Cycle Phase Transition Anatomical Structure Morphogenesis Vascular Endothelial Growth Factor Receptor Signaling Pathway Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Killing Of Cells Of Other Organism Regulation Of Peptidyl-serine Phosphorylation Positive Regulation Of Metabolic Process Regulation Of Cell Cycle Phase Transition Anatomical Structure Formation Involved In Morphogenesis
Tagcloud ?		antibodies antigenic autoantibodies bdc2 cd4 chromogranin employed epitope extension flanking fragments g7 humoral immuno immunostaining islet kcvlevisd molecule nod overlap pancreatic peptide peptides register sections sequence sera titers truncation
Tagcloud (Difference) ?		antibodies antigenic autoantibodies bdc2 cd4 chromogranin employed epitope extension flanking fragments g7 humoral immuno immunostaining islet kcvlevisd molecule nod overlap pancreatic peptide peptides register sections sequence sera titers truncation
Tagcloud (Intersection) ?