KIF3A and KIF3B

Number of citations of the paper that reports this interaction (PMID 7559760)
79

Data Source:
HPRD (in vitro, in vivo)

		KIF3A	KIF3B
Gene Name		kinesin family member 3A	kinesin family member 3B
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Centrosome Cytosol Spindle Microtubule Microtubule Cytoskeleton Kinesin II Complex Extracellular Vesicular Exosome Primary Cilium Ciliary Tip	Centrosome Cytosol Plus-end Kinesin Complex Spindle Microtubule Microtubule Cytoskeleton Membrane Kinesin II Complex Midbody Intraciliary Transport Particle Extracellular Vesicular Exosome Primary Cilium Ciliary Tip
	Molecular Function	Microtubule Motor Activity Protein Binding ATP Binding Microtubule Binding ATP-dependent Microtubule Motor Activity, Plus-end-directed ATPase Activity Spectrin Binding	Microtubule Motor Activity Protein Binding ATP Binding Microtubule Binding ATP-dependent Microtubule Motor Activity, Plus-end-directed ATPase Activity Rho GTPase Binding
	Biological Process	Organelle Organization Microtubule-based Movement Blood Coagulation Metabolic Process Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Neurogenesis Cilium Assembly Cilium Morphogenesis Membrane Organization Plus-end-directed Vesicle Transport Along Microtubule	Organelle Organization Microtubule-based Movement Mitotic Spindle Organization Mitotic Centrosome Separation Determination Of Left/right Symmetry Blood Coagulation Anterograde Axon Cargo Transport Metabolic Process Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Cytoskeleton-dependent Intracellular Transport Positive Regulation Of Cytokinesis Membrane Organization Plus-end-directed Vesicle Transport Along Microtubule Mitotic Spindle Assembly
Pathways		Organelle biogenesis and maintenance Hedgehog 'off' state Kinesins Translocation of GLUT4 to the plasma membrane Assembly of the primary cilium Factors involved in megakaryocyte development and platelet production Intraflagellar transport Hedgehog 'on' state MHC class II antigen presentation Signaling by Hedgehog Adaptive Immune System Activation of SMO	Organelle biogenesis and maintenance MHC class II antigen presentation Kinesins Translocation of GLUT4 to the plasma membrane Assembly of the primary cilium Factors involved in megakaryocyte development and platelet production Intraflagellar transport Adaptive Immune System
Drugs
Diseases
GWAS		Atopic dermatitis ( 23042114 22197932)
Protein-Protein Interactions		13 interactors: APP DISC1 GRB2 KIF3B KIF3C LIG4 MAP3K10 MAP3K11 NEK1 PLEKHA5 PPP1R15A RPGR VHL	10 interactors: APP IFT20 KIF3A KIFAP3 LMO2 LMO4 MAP3K10 MAP3K11 NEDD4L RAB4A
Entrez ID		11127	9371
HPRD ID		05250	04781
Ensembl ID		ENSG00000131437	ENSG00000101350
Uniprot IDs		E9PES4 J3KPF9 Q05CT3 Q9Y496	B4DYF2 O15066
PDB IDs			3B6U
Enriched GO Terms of Interacting Partners?		Microtubule-based Transport Response To Stress Cytoskeleton-dependent Intracellular Transport Microtubule-based Process Cellular Response To Stress Activation Of JNKK Activity Positive Regulation Of Metabolic Process Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Cellular Metabolic Process Microtubule-based Movement Positive Regulation Of Protein Metabolic Process Response To Stimulus Regulation Of Phosphorylation Activation Of MAPK Activity Response To Ionizing Radiation Blood Coagulation Hemostasis Regulation Of Phosphorus Metabolic Process Movement Of Cell Or Subcellular Component Positive Regulation Of Protein Modification Process Response To Radiation Positive Regulation Of Catalytic Activity Cell Death Death Cell Morphogenesis Regulation Of Protein Phosphorylation Response To Abiotic Stimulus Positive Regulation Of MAP Kinase Activity Regulation Of Body Fluid Levels Activation Of JUN Kinase Activity MAPK Cascade Wound Healing Regulation Of Signal Transduction Regulation Of MAPK Cascade Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Signal Transduction Axon Cargo Transport Activation Of Protein Kinase Activity Positive Regulation Of Protein Serine/threonine Kinase Activity Organelle Transport Along Microtubule Signal Transduction By Phosphorylation Response To Wounding Neuron Apoptotic Process Positive Regulation Of Protein Phosphorylation Regulation Of MAP Kinase Activity Regulation Of Signaling Regulation Of Protein Kinase Activity Developmental Process Activation Of MAPKK Activity Regulation Of Protein Metabolic Process	Microtubule-based Transport Cytoskeleton-dependent Intracellular Transport Plus-end-directed Vesicle Transport Along Microtubule Activation Of JNKK Activity Microtubule-based Movement Microtubule-based Process Smoothened Signaling Pathway Regulation Of Endocytosis Cellular Response To Stimulus Immune System Process Vesicle Transport Along Microtubule Positive Regulation Of Receptor-mediated Endocytosis Activation Of JUN Kinase Activity Signal Transduction Antigen Processing And Presentation Intracellular Transport Organelle Transport Along Microtubule Signaling Visual Learning Activation Of MAPKK Activity Cell Communication Visual Behavior Positive Regulation Of JUN Kinase Activity Regulation Of Vesicle-mediated Transport Positive Regulation Of Calcium-dependent Cell-cell Adhesion Opsin Transport Response To Stimulus Associative Learning Regulation Of JUN Kinase Activity JNK Cascade Organelle Localization Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Blood Coagulation Regulation Of Cellular Component Organization Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Hemostasis Establishment Of Localization In Cell Neuron Differentiation Positive Regulation Of Caveolin-mediated Endocytosis Synaptic Growth At Neuromuscular Junction Positive Regulation Of Endocytosis Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II Regulation Of Cellular Process Stress-activated MAPK Cascade Positive Regulation Of Metabolic Process Heart Development Stress-activated Protein Kinase Signaling Cascade Response To Stress Positive Regulation Of Protein Metabolic Process Positive Regulation Of JNK Cascade
Tagcloud ?		aberrant activate advanced anchorage axis benign biopsies catenin causal ck1 correlate dvl2 exogenous gleason hef1 inactivation kinesin mechanistically mmp9 node notion promoted prostate rarely silencing transactivation upregulated upregulation wnt
Tagcloud (Difference) ?		aberrant activate advanced anchorage axis benign biopsies catenin causal ck1 correlate dvl2 exogenous gleason hef1 inactivation kinesin mechanistically mmp9 node notion promoted prostate rarely silencing transactivation upregulated upregulation wnt
Tagcloud (Intersection) ?