CIT and DERA

		CIT	DERA
Description		citron rho-interacting serine/threonine kinase	deoxyribose-phosphate aldolase
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Membrane	Extracellular Region Nucleus Nucleoplasm Cytoplasm Cytosol Secretory Granule Lumen Ficolin-1-rich Granule Lumen
	Molecular Function	Nucleotide Binding Transcription Coactivator Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Zinc Ion Binding Kinase Activity Transferase Activity SH3 Domain Binding Protein Kinase Binding PDZ Domain Binding Protein Serine/threonine Kinase Inhibitor Activity Metal Ion Binding Scaffold Protein Binding Protein Serine Kinase Activity	Deoxyribose-phosphate Aldolase Activity Protein Binding Lyase Activity
	Biological Process	Mitotic Cell Cycle Mitotic Cytokinesis Nervous System Development Cell Differentiation Positive Regulation Of Cytokinesis Regulation Of Actin Cytoskeleton Organization Negative Regulation Of Hippo Signaling Generation Of Neurons Cell Division Neuron Apoptotic Process	Pentose-phosphate Shunt Deoxyribonucleotide Catabolic Process Carbohydrate Catabolic Process Deoxyribonucleoside Catabolic Process Deoxyribose Phosphate Catabolic Process
Pathways		RHO GTPases activate CIT RHO GTPases activate CIT RHOA GTPase cycle RHOB GTPase cycle RHOC GTPase cycle RAC1 GTPase cycle	Neutrophil degranulation Pentose phosphate pathway
Drugs		Fostamatinib
Diseases
GWAS		Mitochondrial heteroplasmy measurement ( 33731350) Number of sexual partners ( 30643258) Urgency urinary incontinence ( 25524241)	Adverse response to chemotherapy (amenorrhea) in breast cancer ( 31371054) Bone mineral density (hip) and age at menarche ( 26312577) Chronotype ( 30696823) Peginterferon alfa-2a treatment response in chronic hepatitis B infection ( 30972912)
Interacting Genes		12 interacting genes: CEBPA DISC1 DLG4 DSCAM GRIN1 GRIN2D MTNR1A RAC1 RHOA RHOB RHOC RND3	1 interacting genes: HSF2
Entrez ID		11113	51071
HPRD ID		09289	13138
Ensembl ID		ENSG00000122966	ENSG00000023697
Uniprot IDs		O14578	E9PPM8 G3V158 Q9Y315
PDB IDs
Enriched GO Terms of Interacting Partners?		Actin Filament Organization Regulation Of Neuronal Synaptic Plasticity Intracellular Signaling Cassette Skeletal Muscle Satellite Cell Migration Intracellular Signal Transduction Cerebral Cortex Cell Migration Signal Transduction Ionotropic Glutamate Receptor Signaling Pathway Positive Regulation Of Excitatory Postsynaptic Potential Small GTPase-mediated Signal Transduction Supramolecular Fiber Organization Telencephalon Cell Migration Positive Regulation Of Phosphate Metabolic Process Positive Regulation Of Lipase Activity Regulation Of Actin Cytoskeleton Organization Positive Regulation Of Cell Communication Positive Regulation Of Signaling Cleavage Furrow Positive Regulation Of Stress Fiber Assembly Forebrain Cell Migration Cell Adhesion Regulation Of System Process Apical Junction Assembly GTPase Activity GTP Binding Dendritic Spine Glutamatergic Synapse Negative Regulation Of Oxidative Phosphorylation Synapse Protein-containing Complex Binding Glutamate Receptor Signaling Pathway Ligand-gated Ion Channel Signaling Pathway Modulation Of Excitatory Postsynaptic Potential Trans-synaptic Signaling Synaptic Signaling Chemical Synaptic Transmission NMDA Glutamate Receptor Activity Glutamate Binding Positive Regulation Of Actin Filament Bundle Assembly Regulation Of Multicellular Organismal Process Regulation Of Actin Filament-based Process Negative Regulation Of Cellular Respiration NMDA Selective Glutamate Receptor Complex Glutamate-gated Calcium Ion Channel Activity Synaptic Membrane Mitotic Cytokinesis Excitatory Chemical Synaptic Transmission Positive Regulation Of Protein-containing Complex Assembly Regulation Of Synaptic Plasticity Regulation Of Synaptic Transmission, Glutamatergic
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?