SPACA9 and EXOC5

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		SPACA9	EXOC5
Description		sperm acrosome associated 9	exocyst complex component 5
Image			No pdb structure
GO Annotations	Cellular Component	Acrosomal Vesicle Nucleus Cytoplasm Cytoskeleton Axonemal Microtubule Cytoplasmic Microtubule Cilium Axoneme Cytoplasmic Vesicle Motile Cilium Ciliary Basal Body Sperm Flagellum Cell Projection Ciliary Base Axonemal Microtubule Doublet Inner Sheath	Exocyst Cytoplasm Cytosol Midbody
	Molecular Function	Protein Binding Microtubule Binding Calcium-dependent Protein Binding	Protein Binding Small GTPase Binding
	Biological Process	Flagellated Sperm Motility Axoneme Assembly	Mitotic Cytokinesis Establishment Of Planar Polarity Exocytosis Post-Golgi Vesicle-mediated Transport Golgi To Plasma Membrane Transport Vesicle Docking Involved In Exocytosis Protein Transport Protein Localization To Plasma Membrane Membrane Fission Vesicle Tethering Involved In Exocytosis Epithelial Cell Apoptotic Process Non-motile Cilium Assembly
Pathways			Translocation of SLC2A4 (GLUT4) to the plasma membrane Insulin processing VxPx cargo-targeting to cilium
Drugs
Diseases
GWAS			Alcohol consumption ( 23743675) Chronotype ( 30696823) HDL cholesterol levels in HIV infection ( 33109212) Response to ranibizumab in age-related macular degeneration (exudative) ( 30054556)
Interacting Genes		11 interacting genes: DDX24 EFEMP2 EXOC5 KRTAP1-1 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 SEPHS1 TSC22D1	41 interacting genes: ACTR3B ADCK1 ARF6 BARD1 BRMS1L C1orf216 CCDC102B CDH2 CREBBP CRYBB1 DEUP1 DNAAF4 EDRF1 ENO2 FGA FRMD6 HDDC3 HGS ICA1 IFT57 KIFC3 MAGEA3 MAGEA6 OAS1 PRKCG PSTPIP1 PTK6 PYCARD RAB14 RAB4A RAB4B RALA SOX10 SPACA9 TBX21 THOC1 TNPO2 TTC23L TXLNB TXNL4A USP2
Entrez ID		11092	10640
HPRD ID		12986	07258
Ensembl ID		ENSG00000165698	ENSG00000070367
Uniprot IDs		Q96E40	O00471
PDB IDs		7UN1 7UNG 8J07
Enriched GO Terms of Interacting Partners?		Keratin Filament Intermediate Filament	G Protein Activity GDP Binding Regulation Of Vesicle-mediated Transport Cytoplasmic Vesicle Membrane GTPase Activity Early Endosome Membrane Regulation Of Endocytosis Insulin-responsive Compartment
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