IDH3B and RAB35

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
HPRD (two hybrid)

		IDH3B	RAB35
Gene Name		isocitrate dehydrogenase 3 (NAD+) beta	RAB35, member RAS oncogene family
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Mitochondrion Mitochondrial Matrix	Golgi Membrane Mitochondrion Endoplasmic Reticulum Membrane Plasma Membrane Coated Pit Endosome Membrane Cell Projection Membrane Melanosome Intercellular Bridge Clathrin-coated Endocytic Vesicle Extracellular Vesicular Exosome
	Molecular Function	Magnesium Ion Binding Isocitrate Dehydrogenase (NAD+) Activity Electron Carrier Activity NAD Binding	GTPase Activity Protein Binding GTP Binding Phosphatidylinositol-4,5-bisphosphate Binding GDP Binding
	Biological Process	Tricarboxylic Acid Cycle Isocitrate Metabolic Process 2-oxoglutarate Metabolic Process NADH Metabolic Process Cellular Metabolic Process Small Molecule Metabolic Process	Cytokinesis Intracellular Protein Transport ER To Golgi Vesicle-mediated Transport Protein Localization Endosomal Transport Antigen Processing And Presentation Neuron Projection Development Endocytic Recycling Rab Protein Signal Transduction Protein Localization To Endosome Plasma Membrane To Endosome Transport Cellular Response To Nerve Growth Factor Stimulus
Pathways		Pyruvate metabolism and Citric Acid (TCA) cycle The citric acid (TCA) cycle and respiratory electron transport Citric acid cycle (TCA cycle)
Drugs		NADH
Diseases
GWAS
Protein-Protein Interactions		6 interactors: ATXN2 IDH3A IDH3G MAPK6 PRMT1 RAB35	7 interactors: APP C2orf44 CBR3 GNPAT IDH3B PTPRS TBPL1
Entrez ID		3420	11021
HPRD ID		05163	05010
Ensembl ID		ENSG00000101365	ENSG00000111737
Uniprot IDs		O43837	G5E9K9 Q15286
PDB IDs			3TW8
Enriched GO Terms of Interacting Partners?		Tricarboxylic Acid Cycle Citrate Metabolic Process Tricarboxylic Acid Metabolic Process Aerobic Respiration Cellular Respiration Neuron Projection Development Negative Regulation Of Megakaryocyte Differentiation Neuron Development Peptidyl-arginine Methylation, To Asymmetrical-dimethyl Arginine Plasma Membrane To Endosome Transport Neuron Differentiation Cell Projection Organization Isocitrate Metabolic Process Energy Derivation By Oxidation Of Organic Compounds Negative Regulation Of Hematopoietic Progenitor Cell Differentiation Protein Localization To Endosome Negative Regulation Of Receptor Internalization Cytoplasmic MRNA Processing Body Assembly Peptidyl-arginine N-methylation Histone H4-R3 Methylation Cerebellar Purkinje Cell Differentiation Stress Granule Assembly Cerebellar Purkinje Cell Layer Morphogenesis Generation Of Precursor Metabolites And Energy Histone Arginine Methylation Peptidyl-arginine Methylation Regulation Of Megakaryocyte Differentiation Generation Of Neurons Negative Regulation Of Receptor-mediated Endocytosis Negative Regulation Of Multicellular Organism Growth Neurogenesis Endocytic Recycling Cerebellar Cortex Formation Cellular Response To Nerve Growth Factor Stimulus Cell Development Cell Differentiation In Hindbrain Regulation Of Hematopoietic Progenitor Cell Differentiation Regulation Of Receptor Internalization Cerebellar Purkinje Cell Layer Development Cerebellar Cortex Morphogenesis	Small Molecule Metabolic Process Synapse Assembly Phosphate-containing Compound Metabolic Process Cerebellum Development Metencephalon Development Synaptic Growth At Neuromuscular Junction Collateral Sprouting In Absence Of Injury Phylloquinone Catabolic Process Hindbrain Development Synapse Organization Brain Development DTTP Biosynthetic Process Cellular Component Assembly Head Development Collateral Sprouting Axon Midline Choice Point Recognition Ether Lipid Biosynthetic Process Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Axon Choice Point Recognition Ketone Catabolic Process Central Nervous System Development Isocitrate Metabolic Process Organophosphate Metabolic Process Neuron Remodeling Ether Lipid Metabolic Process Cognition Deoxyribonucleotide Biosynthetic Process Acrosome Assembly Cofactor Metabolic Process 2-oxoglutarate Metabolic Process Corpus Callosum Development NADH Metabolic Process Extracellular Matrix Organization Extracellular Structure Organization Paranodal Junction Assembly Cellular Copper Ion Homeostasis Glycerol Ether Metabolic Process Copper Ion Homeostasis Suckling Behavior Forebrain Development Deoxyribonucleoside Triphosphate Metabolic Process Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Phosphatidic Acid Biosynthetic Process Phosphatidic Acid Metabolic Process Spermatid Nucleus Differentiation Neuron Maturation MRNA Polyadenylation Regulation Of Epidermal Growth Factor-activated Receptor Activity Myelin Assembly Mating Behavior
Tagcloud ?			bait consists dennd5a domains fluorescently gtp gtpases minimal named neurite never outgrowth pc12 plekhm2 rab1 rab1a rab33 rab41 rab6a rabs rbd35 rufy2 run rusc2 succeeded tagged trafficking trapper
Tagcloud (Difference) ?			bait consists dennd5a domains fluorescently gtp gtpases minimal named neurite never outgrowth pc12 plekhm2 rab1 rab1a rab33 rab41 rab6a rabs rbd35 rufy2 run rusc2 succeeded tagged trafficking trapper
Tagcloud (Intersection) ?