IDH3B and IDH3A

Number of citations of the paper that reports this interaction (PubMedID 10601238)
0

Data Source:
HPRD (in vitro, in vivo)

		IDH3B	IDH3A
Description		isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit beta	isocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha
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GO Annotations	Cellular Component	Nucleus Mitochondrion Mitochondrial Matrix Isocitrate Dehydrogenase Complex (NAD+)	Nucleus Mitochondrion Mitochondrial Matrix Isocitrate Dehydrogenase Complex (NAD+)
	Molecular Function	Magnesium Ion Binding Isocitrate Dehydrogenase (NAD+) Activity Protein Binding Electron Transfer Activity Oxidoreductase Activity, Acting On The CH-OH Group Of Donors, NAD Or NADP As Acceptor NAD Binding	Magnesium Ion Binding Isocitrate Dehydrogenase (NAD+) Activity Protein Binding Oxidoreductase Activity Oxidoreductase Activity, Acting On The CH-OH Group Of Donors, NAD Or NADP As Acceptor Metal Ion Binding NAD Binding
	Biological Process	Tricarboxylic Acid Cycle Isocitrate Metabolic Process	Carbohydrate Metabolic Process Tricarboxylic Acid Cycle Isocitrate Metabolic Process
Pathways		Citric acid cycle (TCA cycle)	Citric acid cycle (TCA cycle) Mitochondrial protein degradation
Drugs		NADH	NADH Manganese Xanthinol Copper
Diseases		Retinitis pigmentosa (RP)
GWAS			Eyebrow thickness ( 26926045)
Interacting Genes		6 interacting genes: ATXN2 IDH3A IDH3G MAPK6 PRMT1 RAB35	7 interacting genes: IDH3B IDH3G MBNL1 PRPF6 RAB4A SF1 SUMO4
Entrez ID		3420	3419
HPRD ID		05163	03094
Ensembl ID		ENSG00000101365	ENSG00000166411
Uniprot IDs		A0A087WZN1 A0A087X2E5 O43837	B4DJB4 B7Z9J8 P50213
PDB IDs		6KDE 6KDF 6KDY 6KE3 7CE3 8GRB 8GRD 8GRU 8GS5	5GRE 5GRF 5GRH 5GRI 5GRL 5YVT 6KDE 6KDF 6KDY 6KE3 6L57 6L59 7CE3 8GRB 8GRD 8GRG 8GRH 8GRU 8GS5
Enriched GO Terms of Interacting Partners?		Isocitrate Dehydrogenase (NAD+) Activity Isocitrate Dehydrogenase Complex (NAD+) Isocitrate Metabolic Process Tricarboxylic Acid Metabolic Process Tricarboxylic Acid Cycle NAD Binding Oxidoreductase Activity, Acting On The CH-OH Group Of Donors, NAD Or NADP As Acceptor GATOR1 Complex Binding Septin Cytoskeleton Protein-arginine Omega-N Monomethyltransferase Activity N-methyltransferase Activity Histone H4R3 Methyltransferase Activity Positive Regulation Of Hemoglobin Biosynthetic Process Peptidyl-arginine Methylation Regulation Of Hemoglobin Biosynthetic Process Mitogen-activated Protein Kinase P38 Binding Response To Methionine Protein-arginine Omega-N Asymmetric Methyltransferase Activity Histone H4 Methyltransferase Activity Cellular Response To Methionine Magnesium Ion Binding	Isocitrate Dehydrogenase (NAD+) Activity Isocitrate Dehydrogenase Complex (NAD+) Isocitrate Metabolic Process Tricarboxylic Acid Metabolic Process Tricarboxylic Acid Cycle NAD Binding Spliceosomal Complex Assembly Oxidoreductase Activity, Acting On The CH-OH Group Of Donors, NAD Or NADP As Acceptor RNA Splicing MRNA Processing Neurotransmitter Receptor Transport Postsynaptic Membrane To Endosome SUMO Ligase Complex MRNA Metabolic Process Insulin-responsive Compartment U2AF Complex MRNA 3'-splice Site Recognition Spliceosomal Complex Magnesium Ion Binding MRNA Splicing, Via Spliceosome Protein-RNA Complex Assembly RNA Splicing, Via Transesterification Reactions
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