IDH3B and IDH3G

Number of citations of the paper that reports this interaction (PMID 10677231)
1

Data Source:
HPRD (in vivo)

		IDH3B	IDH3G
Gene Name		isocitrate dehydrogenase 3 (NAD+) beta	isocitrate dehydrogenase 3 (NAD+) gamma
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Mitochondrion Mitochondrial Matrix	Nucleoplasm Nucleolus Mitochondrion Mitochondrial Matrix
	Molecular Function	Magnesium Ion Binding Isocitrate Dehydrogenase (NAD+) Activity Electron Carrier Activity NAD Binding	Magnesium Ion Binding Isocitrate Dehydrogenase (NAD+) Activity ATP Binding NAD Binding
	Biological Process	Tricarboxylic Acid Cycle Isocitrate Metabolic Process 2-oxoglutarate Metabolic Process NADH Metabolic Process Cellular Metabolic Process Small Molecule Metabolic Process	Carbohydrate Metabolic Process Tricarboxylic Acid Cycle Isocitrate Metabolic Process Cellular Metabolic Process Small Molecule Metabolic Process
Pathways		Pyruvate metabolism and Citric Acid (TCA) cycle The citric acid (TCA) cycle and respiratory electron transport Citric acid cycle (TCA cycle)	Mitochondrial protein import Pyruvate metabolism and Citric Acid (TCA) cycle The citric acid (TCA) cycle and respiratory electron transport Citric acid cycle (TCA cycle)
Drugs		NADH	NADH
Diseases
GWAS
Protein-Protein Interactions		6 interactors: ATXN2 IDH3A IDH3G MAPK6 PRMT1 RAB35	2 interactors: IDH3A IDH3B
Entrez ID		3420	3421
HPRD ID		05163	02100
Ensembl ID		ENSG00000101365	ENSG00000067829
Uniprot IDs		O43837	O15384 P51553
PDB IDs
Enriched GO Terms of Interacting Partners?		Tricarboxylic Acid Cycle Citrate Metabolic Process Tricarboxylic Acid Metabolic Process Aerobic Respiration Cellular Respiration Neuron Projection Development Negative Regulation Of Megakaryocyte Differentiation Neuron Development Peptidyl-arginine Methylation, To Asymmetrical-dimethyl Arginine Plasma Membrane To Endosome Transport Neuron Differentiation Cell Projection Organization Isocitrate Metabolic Process Energy Derivation By Oxidation Of Organic Compounds Negative Regulation Of Hematopoietic Progenitor Cell Differentiation Protein Localization To Endosome Negative Regulation Of Receptor Internalization Cytoplasmic MRNA Processing Body Assembly Peptidyl-arginine N-methylation Histone H4-R3 Methylation Cerebellar Purkinje Cell Differentiation Stress Granule Assembly Cerebellar Purkinje Cell Layer Morphogenesis Generation Of Precursor Metabolites And Energy Histone Arginine Methylation Peptidyl-arginine Methylation Regulation Of Megakaryocyte Differentiation Generation Of Neurons Negative Regulation Of Receptor-mediated Endocytosis Negative Regulation Of Multicellular Organism Growth Neurogenesis Endocytic Recycling Cerebellar Cortex Formation Cellular Response To Nerve Growth Factor Stimulus Cell Development Cell Differentiation In Hindbrain Regulation Of Hematopoietic Progenitor Cell Differentiation Regulation Of Receptor Internalization Cerebellar Purkinje Cell Layer Development Cerebellar Cortex Morphogenesis	Tricarboxylic Acid Cycle Citrate Metabolic Process Tricarboxylic Acid Metabolic Process Aerobic Respiration Cellular Respiration Energy Derivation By Oxidation Of Organic Compounds Generation Of Precursor Metabolites And Energy Isocitrate Metabolic Process 2-oxoglutarate Metabolic Process NADH Metabolic Process Carboxylic Acid Metabolic Process Organic Acid Metabolic Process Oxidation-reduction Process NAD Metabolic Process Nicotinamide Nucleotide Metabolic Process Dicarboxylic Acid Metabolic Process Small Molecule Metabolic Process Cofactor Metabolic Process
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