RCBTB2 and UBE2E3

Number of citations of the paper that reports this interaction (PMID 19256485)
6

Data Source:
BioGRID (pull down)

		RCBTB2	UBE2E3
Gene Name		regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2	ubiquitin-conjugating enzyme E2E 3
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component		Nucleus Cytoplasm
	Molecular Function	Ran Guanyl-nucleotide Exchange Factor Activity	Ubiquitin-protein Transferase Activity ATP Binding Ligase Activity
	Biological Process	Positive Regulation Of Ran GTPase Activity	Regulation Of Growth Protein K63-linked Ubiquitination Protein K48-linked Ubiquitination Protein K11-linked Ubiquitination
Pathways			Antigen processing: Ubiquitination & Proteasome degradation Class I MHC mediated antigen processing & presentation Adaptive Immune System
Drugs
Diseases
GWAS			Celiac disease ( 20190752) Obesity ( 21552555)
Protein-Protein Interactions		6 interactors: COPS4 CUL3 FARS2 PDE4B UBE2E3 UBE2I	75 interactors: ACVR1 ARID3A ARIH2 ATXN1 BARD1 BRCA1 CADPS2 CHFR CHUK CNOT4 CUL1 CUL3 CUL4A DTX3 DTX3L DZIP3 HERC4 HTT IPO11 ITCH KLHL42 MARCH5 MDM2 MID1 MID2 MKRN3 MUL1 NEDD4L NFKBIA RBX1 RCBTB1 RCBTB2 RFWD3 RING1 RMND5B RNF10 RNF11 RNF111 RNF114 RNF115 RNF13 RNF130 RNF14 RNF150 RNF165 RNF166 RNF167 RNF181 RNF185 RNF2 RNF25 RNF4 RNF43 RNF5 RNF8 SAE1 SIAH1 SPOP STUB1 TGFBR1 TRIM2 TRIM27 TRIM32 TRIM37 TRIM38 TRIM39 TRIM45 TRIM50 UBA1 UBC UBOX5 UFM1 WWP2 ZNRF1 ZNRF4
Entrez ID		1102	10477
HPRD ID		04631	05000
Ensembl ID		ENSG00000136161	ENSG00000170035
Uniprot IDs		B4DWG0 O95199	Q969T4
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of SUMO Transferase Activity Protein Ubiquitination Protein Modification By Small Protein Conjugation Negative Regulation Of Relaxation Of Cardiac Muscle Trophectodermal Cellular Morphogenesis Protein Polyubiquitination Cellular Protein Metabolic Process Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase By Cyclin Degradation Chromosome Segregation Phenylalanyl-tRNA Aminoacylation Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Regulation Of High Voltage-gated Calcium Channel Activity Regulation Of Relaxation Of Cardiac Muscle Proteasomal Protein Catabolic Process Positive Regulation Of Mitotic Metaphase/anaphase Transition Regulation Of Relaxation Of Muscle Cullin Deneddylation Positive Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Mitotic Nuclear Division Protein Deneddylation Embryonic Cleavage Protein Metabolic Process Neutrophil Homeostasis CAMP Catabolic Process Stress Fiber Assembly Positive Regulation Of Chromosome Segregation Cellular Protein Modification Process Cellular Response To Epinephrine Stimulus Cell Division Response To Epinephrine Cyclic Nucleotide Catabolic Process COPII Vesicle Coating Regulation Of Voltage-gated Calcium Channel Activity COPII-coated Vesicle Budding Protein K11-linked Ubiquitination Negative Regulation Of Rho Protein Signal Transduction Purine Ribonucleotide Catabolic Process Ubiquitin-dependent Protein Catabolic Process Cellular Metabolic Process Modification-dependent Protein Catabolic Process Protein Sumoylation Trophectodermal Cell Differentiation Cellular Response To Catecholamine Stimulus Mitotic Metaphase Plate Congression Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Vesicle Targeting, To, From Or Within Golgi Cellular Protein Catabolic Process Metaphase Plate Congression	Protein Modification By Small Protein Conjugation Protein Ubiquitination Cellular Protein Modification Process Protein Polyubiquitination Cellular Protein Metabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Protein Metabolic Process Protein Catabolic Process Ubiquitin-dependent Protein Catabolic Process Cellular Macromolecule Catabolic Process Protein Autoubiquitination Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Cellular Metabolic Process Catabolic Process Protein K63-linked Ubiquitination Proteolysis Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Protein K48-linked Ubiquitination Protein Monoubiquitination Metabolic Process Regulation Of Signal Transduction Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Positive Regulation Of NF-kappaB Transcription Factor Activity Negative Regulation Of Cell Cycle Regulation Of Cell Cycle Negative Regulation Of Signal Transduction Regulation Of Signaling Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Positive Regulation Of Protein Catabolic Process Negative Regulation Of Signaling Histone Ubiquitination Histone H2A Ubiquitination Regulation Of Protein Catabolic Process Cell Cycle Histone Monoubiquitination Response To Stress Apoptotic Process Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Type I Interferon Production Nucleotide-binding Oligomerization Domain Containing Signaling Pathway Programmed Cell Death Cellular Response To Stress Protein K6-linked Ubiquitination Cell Cycle Process Regulation Of Gene Expression Positive Regulation Of Metabolic Process Mitotic Cell Cycle
Tagcloud ?			conjugating cytoprotective degraded extracting govern homeostasis imp import importin keap1 locales localizes mitochondria nrf2 outer p45 partitioning perinuclear prematurely relocalizes repressive restore restrict restricting subcellular tightly transcriptionally unresolved
Tagcloud (Difference) ?			conjugating cytoprotective degraded extracting govern homeostasis imp import importin keap1 locales localizes mitochondria nrf2 outer p45 partitioning perinuclear prematurely relocalizes repressive restore restrict restricting subcellular tightly transcriptionally unresolved
Tagcloud (Intersection) ?