RCBTB2 and FARS2

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		RCBTB2	FARS2
Gene Name		regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2	phenylalanyl-tRNA synthetase 2, mitochondrial
Image		No pdb structure
Gene Ontology Annotations	Cellular Component		Mitochondrial Matrix
	Molecular Function	Ran Guanyl-nucleotide Exchange Factor Activity	TRNA Binding Magnesium Ion Binding Phenylalanine-tRNA Ligase Activity ATP Binding
	Biological Process	Positive Regulation Of Ran GTPase Activity	TRNA Aminoacylation For Protein Translation Phenylalanyl-tRNA Aminoacylation TRNA Processing Gene Expression
Pathways			tRNA Aminoacylation Mitochondrial tRNA aminoacylation
Drugs			L-Phenylalanine
Diseases
GWAS			Obesity (early onset extreme) ( 23563609)
Protein-Protein Interactions		6 interactors: COPS4 CUL3 FARS2 PDE4B UBE2E3 UBE2I	23 interactors: ADAMTSL4 AGTRAP APPL1 CALCOCO2 CMTM5 HMBOX1 IKZF3 KRT13 KRT31 KRT40 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-9 MID2 MKRN3 NOTCH2NL RCBTB2 STX11 TADA2A TFCP2 TRIM27 TRIM54
Entrez ID		1102	10667
HPRD ID		04631	09946
Ensembl ID		ENSG00000136161	ENSG00000145982
Uniprot IDs		B4DWG0 O95199	O95363
PDB IDs			3CMQ 3HFV 3TEG 3TUP
Enriched GO Terms of Interacting Partners?		Positive Regulation Of SUMO Transferase Activity Protein Ubiquitination Protein Modification By Small Protein Conjugation Negative Regulation Of Relaxation Of Cardiac Muscle Trophectodermal Cellular Morphogenesis Protein Polyubiquitination Cellular Protein Metabolic Process Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase By Cyclin Degradation Chromosome Segregation Phenylalanyl-tRNA Aminoacylation Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Regulation Of High Voltage-gated Calcium Channel Activity Regulation Of Relaxation Of Cardiac Muscle Proteasomal Protein Catabolic Process Positive Regulation Of Mitotic Metaphase/anaphase Transition Regulation Of Relaxation Of Muscle Cullin Deneddylation Positive Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Mitotic Nuclear Division Protein Deneddylation Embryonic Cleavage Protein Metabolic Process Neutrophil Homeostasis CAMP Catabolic Process Stress Fiber Assembly Positive Regulation Of Chromosome Segregation Cellular Protein Modification Process Cellular Response To Epinephrine Stimulus Cell Division Response To Epinephrine Cyclic Nucleotide Catabolic Process COPII Vesicle Coating Regulation Of Voltage-gated Calcium Channel Activity COPII-coated Vesicle Budding Protein K11-linked Ubiquitination Negative Regulation Of Rho Protein Signal Transduction Purine Ribonucleotide Catabolic Process Ubiquitin-dependent Protein Catabolic Process Cellular Metabolic Process Modification-dependent Protein Catabolic Process Protein Sumoylation Trophectodermal Cell Differentiation Cellular Response To Catecholamine Stimulus Mitotic Metaphase Plate Congression Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Vesicle Targeting, To, From Or Within Golgi Cellular Protein Catabolic Process Metaphase Plate Congression	Negative Regulation Of Viral Release From Host Cell Negative Regulation Of Viral Transcription Regulation Of Viral Release From Host Cell
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