CLP1 and CREB3

Number of citations of the paper that reports this interaction (PMID 11384994)
6

Data Source:
BioGRID (pull down)

		CLP1	CREB3
Gene Name		cleavage and polyadenylation factor I subunit 1	cAMP responsive element binding protein 3
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	TRNA-intron Endonuclease Complex Nucleus Nucleoplasm Cytoplasm MRNA Cleavage Factor Complex	Golgi Membrane Nucleus Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Cytosol Membrane Integral Component Of Membrane Nuclear Body Integral Component Of Endoplasmic Reticulum Membrane Neuronal Cell Body
	Molecular Function	ATP Binding ATP-dependent Polydeoxyribonucleotide 5'-hydroxyl-kinase Activity Polydeoxyribonucleotide Kinase Activity ATP-dependent Polyribonucleotide 5'-hydroxyl-kinase Activity	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription DNA Binding Chromatin Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Binding CAMP Response Element Binding Protein Binding CCR1 Chemokine Receptor Binding CAMP Response Element Binding Protein Homodimerization Activity Protein Dimerization Activity
	Biological Process	MRNA Splicing, Via Spliceosome Transcription From RNA Polymerase II Promoter Termination Of RNA Polymerase II Transcription MRNA Polyadenylation MRNA Cleavage TRNA Splicing, Via Endonucleolytic Cleavage And Ligation RNA Splicing Gene Expression Phosphorylation Cerebellar Cortex Development Targeting Of MRNA For Destruction Involved In RNA Interference MRNA 3'-end Processing SiRNA Loading Onto RISC Involved In RNA Interference	Regulation Of Cell Growth Positive Regulation Of Defense Response To Virus By Host Transcription, DNA-templated Transcription From RNA Polymerase II Promoter Chemotaxis Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Unfolded Protein Response Viral Process Establishment Of Viral Latency Release From Viral Latency Positive Regulation Of Cell Migration Response To Endoplasmic Reticulum Stress Regulation Of Cell Proliferation Cytoplasmic Sequestering Of Transcription Factor Negative Regulation Of Cell Cycle Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Induction Of Positive Chemotaxis Positive Regulation Of Calcium Ion Transport Positive Regulation Of Monocyte Chemotaxis Positive Regulation Of Deacetylase Activity Negative Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Ligand-dependent Nuclear Receptor Transcription Coactivator Activity
Pathways		mRNA Splicing Processing of Capped Intron-Containing Pre-mRNA RNA Polymerase II Transcription Processing of Capped Intronless Pre-mRNA mRNA Splicing - Major Pathway Cleavage of Growing Transcript in the Termination Region RNA Polymerase II Transcription Termination Processing of Intronless Pre-mRNAs mRNA 3'-end processing
Drugs
Diseases
GWAS
Protein-Protein Interactions		5 interactors: APP CPSF3 CREB3 HCFC1 NUDT21	25 interactors: APPBP2 ATF3 ATF4 BCAT2 BNIP2 CCR1 CEBPG CLP1 CREB3L1 CREB3L3 DDIT3 EMD HCFC1 HDAC3 JUN MALL NFE2L2 NFE2L3 NFIL3 OS9 RABAC1 RRAS2 SQLE STX8 TTLL5
Entrez ID		10978	10488
HPRD ID		16382	07339
Ensembl ID		ENSG00000172409	ENSG00000107175
Uniprot IDs		Q92989	O43889
PDB IDs
Enriched GO Terms of Interacting Partners?		MRNA Polyadenylation RNA Polyadenylation Release From Viral Latency MRNA 3'-end Processing RNA 3'-end Processing Transcription From RNA Polymerase II Promoter Termination Of RNA Polymerase II Transcription RNA Metabolic Process MRNA Processing Gene Expression DNA-templated Transcription, Termination MRNA Metabolic Process RNA Processing Negative Regulation Of Ligand-dependent Nuclear Receptor Transcription Coactivator Activity Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Synaptic Growth At Neuromuscular Junction Transcription, DNA-templated Cellular Nitrogen Compound Metabolic Process RNA Biosynthetic Process Regulation Of Cell Cycle Collateral Sprouting In Absence Of Injury Nitrogen Compound Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Unfolded Protein Response MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Collateral Sprouting Axon Midline Choice Point Recognition Histone MRNA 3'-end Processing Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Positive Regulation Of Deacetylase Activity Axon Choice Point Recognition Positive Regulation Of Cell Cycle Positive Regulation Of Transcription, DNA-templated Neuron Remodeling Establishment Of Viral Latency RNA Splicing Positive Regulation Of Monocyte Chemotaxis Positive Regulation Of Macromolecule Biosynthetic Process Cellular Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Macromolecule Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Histone H4-K5 Acetylation Histone H4-K8 Acetylation Regulation Of Monocyte Chemotaxis Histone H4-K16 Acetylation Positive Regulation Of Defense Response To Virus By Host	Response To Endoplasmic Reticulum Stress Transcription From RNA Polymerase II Promoter Endoplasmic Reticulum Unfolded Protein Response Cellular Response To Unfolded Protein ER-nucleus Signaling Pathway Cellular Response To Topologically Incorrect Protein Response To Unfolded Protein Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated RNA Biosynthetic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Cellular Response To Organic Substance Positive Regulation Of Gene Expression Response To Organic Substance Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Positive Regulation Of Transcription, DNA-templated Regulation Of DNA-templated Transcription In Response To Stress RNA Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Gene Expression Biosynthetic Process Cellular Macromolecule Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Macromolecule Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Gene Expression Positive Regulation Of Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Oxidative Stress Cellular Aromatic Compound Metabolic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Nucleic Acid-templated Transcription Cellular Response To Stress Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Endoplasmic Reticulum Stress Cellular Nitrogen Compound Metabolic Process Activation Of Signaling Protein Activity Involved In Unfolded Protein Response Nucleobase-containing Compound Metabolic Process Positive Regulation Of Nuclease Activity Regulation Of Phosphorylation Circadian Rhythm Negative Regulation Of Biosynthetic Process Positive Regulation Of Neuron Apoptotic Process Response To Stress Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Regulation Of Gene Expression Positive Regulation Of Neuron Death Regulation Of Phosphorus Metabolic Process
Tagcloud ?		aberrant axonal dead degeneration denervation determining elusive fatal fragments inactivation junctions k link mechanistic mechanistically motor nerves neuromuscular neuron paralysis progressive rescue rescues respiratory sensitize trna trp53 uncover weakness	atf6 beyond bzip elucidate endoplasmic expands inducers intramembrane knockouts l4 mammals members microarray proteolysis proteolytic proteolytically recognition reticulum rnai screens similarity spectrum stimulate subfamily thought tumorigenesis unfolded upr
Tagcloud (Difference) ?		aberrant axonal dead degeneration denervation determining elusive fatal fragments inactivation junctions k link mechanistic mechanistically motor nerves neuromuscular neuron paralysis progressive rescue rescues respiratory sensitize trna trp53 uncover weakness	atf6 beyond bzip elucidate endoplasmic expands inducers intramembrane knockouts l4 mammals members microarray proteolysis proteolytic proteolytically recognition reticulum rnai screens similarity spectrum stimulate subfamily thought tumorigenesis unfolded upr
Tagcloud (Intersection) ?