SEC61B and SERP1

Number of citations of the paper that reports this interaction (PMID 10601334)
18

Data Source:
HPRD (in vivo)

		SEC61B	SERP1
Gene Name		Sec61 beta subunit	stress-associated endoplasmic reticulum protein 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Endoplasmic Reticulum Membrane Integral Component Of Membrane Endoplasmic Reticulum Sec Complex	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Ribosome Cytoplasmic Microtubule Integral Component Of Membrane
	Molecular Function	Protein Binding Poly(A) RNA Binding Epidermal Growth Factor Binding
	Biological Process	Protein Import Into Nucleus, Translocation Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I, TAP-dependent Translation SRP-dependent Cotranslational Protein Targeting To Membrane Gene Expression ER-associated Ubiquitin-dependent Protein Catabolic Process Retrograde Protein Transport, ER To Cytosol Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I Cellular Protein Metabolic Process	Skeletal System Development Glucose Metabolic Process Cellular Protein Modification Process Protein Glycosylation Response To Stress Activation Of Signaling Protein Activity Involved In Unfolded Protein Response Plasma Membrane Organization Post-embryonic Development Multicellular Organismal Aging Protein Transport Endoplasmic Reticulum Unfolded Protein Response Positive Regulation Of Insulin Secretion Cellular Protein Metabolic Process Positive Regulation Of Translation Positive Regulation Of Organ Growth Muscle Organ Morphogenesis Positive Regulation Of Growth Hormone Secretion
Pathways		Translation SRP-dependent cotranslational protein targeting to membrane Class I MHC mediated antigen processing & presentation Antigen processing-Cross presentation ER-Phagosome pathway Adaptive Immune System	IRE1alpha activates chaperones XBP1(S) activates chaperone genes Unfolded Protein Response (UPR)
Drugs
Diseases
GWAS
Protein-Protein Interactions		12 interactors: APOB ARL6 ASNA1 ATP13A2 BAG6 GET4 SEC63 SERP1 SPC25 TRAM1 UBC UBL4A	7 interactors: APP CANX SCNN1A SCNN1G SEC61A1 SEC61B TMEM79
Entrez ID		10952	27230
HPRD ID		06715	18037
Ensembl ID		ENSG00000106803	ENSG00000120742
Uniprot IDs		P60468	Q9Y6X1
PDB IDs
Enriched GO Terms of Interacting Partners?		Establishment Of Protein Localization To Membrane Membrane Organization Protein Localization To Membrane Protein Insertion Into ER Membrane Protein Localization To Organelle Establishment Of Protein Localization Protein Insertion Into Membrane Protein Localization Tail-anchored Membrane Protein Insertion Into ER Membrane Endoplasmic Reticulum Organization Transport Cellular Protein Localization Cellular Localization Protein Targeting To Membrane Endomembrane System Organization SRP-dependent Cotranslational Protein Targeting To Membrane Cotranslational Protein Targeting To Membrane Protein Targeting To ER Establishment Of Protein Localization To Endoplasmic Reticulum Protein Transport Protein Localization To Endoplasmic Reticulum Protein Targeting Multicellular Organismal Aging Organelle Organization Posttranslational Protein Targeting To Membrane, Translocation Intracellular Transport Establishment Of Protein Localization To Organelle Intracellular Protein Transport Intermembrane Transport Signal Transduction By P53 Class Mediator Internal Peptidyl-lysine Acetylation Peptidyl-lysine Acetylation Internal Protein Amino Acid Acetylation Establishment Of Localization In Cell Protein Acetylation Post-embryonic Development Glucose Metabolic Process Receptor Transactivation Cellular Response To Manganese Ion Response To Endoplasmic Reticulum Stress Posttranslational Protein Targeting To Membrane Mammary Gland Branching Involved In Thelarche Protein Catabolic Process Response To Selenium Ion Positive Regulation Of Growth Hormone Secretion Very-low-density Lipoprotein Particle Assembly Intracellular Receptor Signaling Pathway Cytoplasmic Transport Regulation Of Insulin Secretion Triglyceride Mobilization	Multicellular Organismal Water Homeostasis Water Homeostasis Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I Regulation Of Body Fluid Levels Transport Sodium Ion Homeostasis Antigen Processing And Presentation Of Peptide Antigen Chemical Homeostasis Antigen Processing And Presentation Excretion Establishment Of Localization In Cell Sensory Perception Of Taste Cellular Localization Metal Ion Homeostasis Secretion By Cell SRP-dependent Cotranslational Protein Targeting To Membrane Homeostatic Process Cotranslational Protein Targeting To Membrane Protein Targeting To ER Establishment Of Protein Localization To Endoplasmic Reticulum Ion Homeostasis Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I, TAP-dependent Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I Protein Localization To Endoplasmic Reticulum Synaptic Growth At Neuromuscular Junction Secretion Cell Maturation Cell Growth Collateral Sprouting In Absence Of Injury Cuticle Development Protein Targeting To Membrane Cornification Collateral Sprouting Axon Midline Choice Point Recognition Retrograde Protein Transport, ER To Cytosol Sodium Ion Transmembrane Transport Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Immune System Process Axon Choice Point Recognition Establishment Of Protein Localization To Membrane Posttranslational Protein Targeting To Membrane Sodium Ion Transport Neuron Remodeling Neurological System Process Exocytosis Establishment Of Protein Localization To Organelle Protein Localization To Membrane Establishment Of Skin Barrier Cellular Copper Ion Homeostasis Regulation Of Water Loss Via Skin
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