SEC61B and SEC63

Number of citations of the paper that reports this interaction (PMID 10799540)
33

Data Source:
HPRD (in vitro)

		SEC61B	SEC63
Gene Name		Sec61 beta subunit	SEC63 homolog (S. cerevisiae)
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Endoplasmic Reticulum Membrane Integral Component Of Membrane Endoplasmic Reticulum Sec Complex	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding Poly(A) RNA Binding Epidermal Growth Factor Binding	Receptor Activity Protein Binding Protein Transporter Activity Poly(A) RNA Binding
	Biological Process	Protein Import Into Nucleus, Translocation Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I, TAP-dependent Translation SRP-dependent Cotranslational Protein Targeting To Membrane Gene Expression ER-associated Ubiquitin-dependent Protein Catabolic Process Retrograde Protein Transport, ER To Cytosol Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I Cellular Protein Metabolic Process	Liver Development Protein Targeting To Membrane SRP-dependent Cotranslational Protein Targeting To Membrane Posttranslational Protein Targeting To Membrane Nitrogen Compound Metabolic Process Multicellular Organismal Aging Posttranslational Protein Targeting To Membrane, Translocation Renal System Development
Pathways		Translation SRP-dependent cotranslational protein targeting to membrane Class I MHC mediated antigen processing & presentation Antigen processing-Cross presentation ER-Phagosome pathway Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		12 interactors: APOB ARL6 ASNA1 ATP13A2 BAG6 GET4 SEC63 SERP1 SPC25 TRAM1 UBC UBL4A	2 interactors: SEC61B SEC62
Entrez ID		10952	11231
HPRD ID		06715	09783
Ensembl ID		ENSG00000106803	ENSG00000025796
Uniprot IDs		P60468	Q9UGP8
PDB IDs
Enriched GO Terms of Interacting Partners?		Establishment Of Protein Localization To Membrane Membrane Organization Protein Localization To Membrane Protein Insertion Into ER Membrane Protein Localization To Organelle Establishment Of Protein Localization Protein Insertion Into Membrane Protein Localization Tail-anchored Membrane Protein Insertion Into ER Membrane Endoplasmic Reticulum Organization Transport Cellular Protein Localization Cellular Localization Protein Targeting To Membrane Endomembrane System Organization SRP-dependent Cotranslational Protein Targeting To Membrane Cotranslational Protein Targeting To Membrane Protein Targeting To ER Establishment Of Protein Localization To Endoplasmic Reticulum Protein Transport Protein Localization To Endoplasmic Reticulum Protein Targeting Multicellular Organismal Aging Organelle Organization Posttranslational Protein Targeting To Membrane, Translocation Intracellular Transport Establishment Of Protein Localization To Organelle Intracellular Protein Transport Intermembrane Transport Signal Transduction By P53 Class Mediator Internal Peptidyl-lysine Acetylation Peptidyl-lysine Acetylation Internal Protein Amino Acid Acetylation Establishment Of Localization In Cell Protein Acetylation Post-embryonic Development Glucose Metabolic Process Receptor Transactivation Cellular Response To Manganese Ion Response To Endoplasmic Reticulum Stress Posttranslational Protein Targeting To Membrane Mammary Gland Branching Involved In Thelarche Protein Catabolic Process Response To Selenium Ion Positive Regulation Of Growth Hormone Secretion Very-low-density Lipoprotein Particle Assembly Intracellular Receptor Signaling Pathway Cytoplasmic Transport Regulation Of Insulin Secretion Triglyceride Mobilization	Cotranslational Protein Targeting To Membrane Protein Targeting To ER Establishment Of Protein Localization To Endoplasmic Reticulum Protein Localization To Endoplasmic Reticulum Protein Targeting To Membrane Establishment Of Protein Localization To Membrane Establishment Of Protein Localization To Organelle Protein Localization To Membrane Protein Targeting Retrograde Protein Transport, ER To Cytosol Protein Localization To Organelle Posttranslational Protein Targeting To Membrane Cytoplasmic Transport Membrane Organization Intracellular Protein Transport Protein Import Into Nucleus, Translocation ER-associated Ubiquitin-dependent Protein Catabolic Process Cellular Protein Localization Protein Transport Establishment Of Protein Localization Intracellular Transport Protein Localization Establishment Of Localization In Cell SRP-dependent Cotranslational Protein Targeting To Membrane Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I, TAP-dependent Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I Protein Import Into Nucleus Nuclear Import Cellular Localization Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I Protein Import Protein Localization To Nucleus Antigen Processing And Presentation Of Peptide Antigen Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Nucleocytoplasmic Transport Nuclear Transport Antigen Processing And Presentation
Tagcloud ?			a181 apparatus bip cytosolically defect inability kar2 kar2p kurihara lies lumenal membranebound mimics nelson passage polypeptide relieve rose sanders schekman sec62 stalling suppressors transit transiting unimpaired vogel whitfield
Tagcloud (Difference) ?			a181 apparatus bip cytosolically defect inability kar2 kar2p kurihara lies lumenal membranebound mimics nelson passage polypeptide relieve rose sanders schekman sec62 stalling suppressors transit transiting unimpaired vogel whitfield
Tagcloud (Intersection) ?