SERP1 and FKBP7

Number of citations of the paper that reports this interaction (PubMedID 36949045)
82

Data Source:
BioGRID (two hybrid)

		SERP1	FKBP7
Description		stress associated endoplasmic reticulum protein 1	FKBP prolyl isomerase 7
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytosol Ribosome Cytoplasmic Microtubule Membrane	Endoplasmic Reticulum Endoplasmic Reticulum Lumen
	Molecular Function	Protein Binding	Peptidyl-prolyl Cis-trans Isomerase Activity Calcium Ion Binding Protein Binding FK506 Binding Isomerase Activity Metal Ion Binding
	Biological Process	Skeletal System Development Glucose Metabolic Process Protein Glycosylation Response To Unfolded Protein Plasma Membrane Organization Post-embryonic Development Protein Transport Insulin Secretion Endoplasmic Reticulum Unfolded Protein Response Positive Regulation Of Insulin Secretion Protein Modification Process Positive Regulation Of Translation Positive Regulation Of Organ Growth Muscle Organ Morphogenesis Positive Regulation Of Growth Hormone Secretion
Pathways		XBP1(S) activates chaperone genes Insertion of tail-anchored proteins into the endoplasmic reticulum membrane Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
Drugs
Diseases
GWAS		Academic attainment (English) ( 33594131)	Alanine aminotransferase levels ( 33547301) Appendicular lean mass ( 33097823) Aspartate aminotransferase levels ( 33547301) Atrial fibrillation ( 30061737) Blood protein levels ( 30072576) Rapid functional decline in sporadic amyotrophic lateral sclerosis ( 26746183) Refractive error ( 32231278)
Interacting Genes		56 interacting genes: ALG3 APH1A APP AQP6 AQP8 BIK BSCL2 CANX CD74 CD79A CRB3 CYBRD1 EBP FAM174A FAM209A FAM210B FKBP7 FRMD3 GJB3 GJB5 GKN1 GPR37L1 GPX8 HSD17B13 IL3RA JAGN1 KCNF1 KIR3DL3 LHFPL5 LMNA MTIF3 PLPPR1 REEP4 SAR1A SCNN1A SCNN1G SEC11C SEC61A1 SEC61B SLC10A1 SLC10A6 SLC18A1 SLC22A1 SLC22A2 SLC35H1 SLC71A2 SSMEM1 STX1A STX2 STX4 TIMMDC1 TLCD4 TMEM14B TMEM52B TMEM79 TNFRSF9	107 interacting genes: ABHD16A ADGRE2 ADIPOQ AP1M1 APOD ASPH BET1 BMP10 BRICD5 C3orf52 CD81 CDIPT CDS2 CERCAM CFTR CIAO2A CLCA4 CLDN19 CNIH1 CTSA CXCL16 CYB561D2 CYB5B DIABLO ERMP1 FAM3C FARS2 GET3 H4C7 HHATL HMOX1 HSBP1L1 HTATIP2 IER3 IFITM3 IGFBP5 IRF2 JOSD2 LAT LNPEP MAN2B2 MIEF2 MRM1 NFU1 NKG7 NPFFR2 OCIAD1 OXNAD1 PBX3 PCYT1A PEX16 PEX19 PLLP PLP1 PLP2 PLPP6 PPIF PRMT6 PTCD1 PTPN9 RBFA RPRM RUSF1 SELENOK SERP1 SGTA SLC30A3 SLC38A7 SLC7A14 SNX1 SNX12 STATH STX7 STX8 SUCLA2 TARS2 TCP11X2 TECR TF THAP4 THSD7B TMEM108 TMEM120B TMEM147 TMEM14A TMEM229B TMEM239 TMEM54 TMEM86A TMEM86B TMEM97 TRAM1L1 TSPAN2 TSPO2 TTPA TXNDC12 UBIAD1 UBQLN4 UNC93B1 UPK1B UPK2 VSTM4 WFDC2 WIPI2 YIPF4 YIPF6 ZFPL1
Entrez ID		27230	51661
HPRD ID		18037	08451
Ensembl ID		ENSG00000120742	ENSG00000079150
Uniprot IDs		Q9Y6X1	B4DRE2 Q9Y680
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Transmembrane Transport Norepinephrine Uptake Endoplasmic Reticulum Serotonin Uptake Norepinephrine Transport Monoamine Transmembrane Transporter Activity Amine Transport Catecholamine Uptake Dopamine Uptake Serotonin Transport Pyrimidine Nucleoside Transmembrane Transporter Activity Protein Binding Neurotransmitter Transport Apical Plasma Membrane Mitochondrial Membrane Endoplasmic Reticulum Membrane Putrescine Transmembrane Transporter Activity Monoatomic Ion Transport Neurotransmitter Reuptake Dopamine Transport Sensory Perception Of Salty Taste Xenobiotic Transmembrane Transporter Activity Acetylcholine Transport Epinephrine Transport Spermidine Transmembrane Transport Putrescine Transport Spermidine Transmembrane Transporter Activity Acetylcholine Transmembrane Transporter Activity Bile Acid:sodium Symporter Activity Spermidine Transport Thiamine Transmembrane Transporter Activity Thiamine Transport Quaternary Ammonium Group Transmembrane Transporter Activity Thiamine Transmembrane Transport Monoamine Transport Neurotransmitter Uptake Lumenal Side Of Endoplasmic Reticulum Membrane Basolateral Plasma Membrane External Side Of Plasma Membrane Cornified Envelope Assembly Monoatomic Cation Transport Xenobiotic Transport Across Blood-brain Barrier Sec61 Translocon Complex Import Into Cell Organic Cation Transport Organic Hydroxy Compound Transport Cellular Response To Aldosterone Sodium Channel Complex Toxin Transmembrane Transporter Activity	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Protein Binding Chloride Channel Inhibitor Activity Regulation Of Cellular Localization Cellular Localization Protein Insertion Into ER Membrane Transferrin Receptor Binding Alkenylglycerophosphocholine Hydrolase Activity Lysosome Peroxisome Membrane Biogenesis Intraciliary Transport Particle B Binding Cholesterol Binding Establishment Of Localization In Cell
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