SEC61B and TRAM1

Number of citations of the paper that reports this interaction (PMID 9512475)
6

Data Source:
HPRD (in vivo)

		SEC61B	TRAM1
Gene Name		Sec61 beta subunit	translocation associated membrane protein 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Endoplasmic Reticulum Membrane Integral Component Of Membrane Endoplasmic Reticulum Sec Complex	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding Poly(A) RNA Binding Epidermal Growth Factor Binding	Receptor Activity Protein Binding
	Biological Process	Protein Import Into Nucleus, Translocation Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I, TAP-dependent Translation SRP-dependent Cotranslational Protein Targeting To Membrane Gene Expression ER-associated Ubiquitin-dependent Protein Catabolic Process Retrograde Protein Transport, ER To Cytosol Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I Cellular Protein Metabolic Process	Translation Cotranslational Protein Targeting To Membrane SRP-dependent Cotranslational Protein Targeting To Membrane Gene Expression Viral Process Cellular Protein Metabolic Process
Pathways		Translation SRP-dependent cotranslational protein targeting to membrane Class I MHC mediated antigen processing & presentation Antigen processing-Cross presentation ER-Phagosome pathway Adaptive Immune System	Translation SRP-dependent cotranslational protein targeting to membrane
Drugs
Diseases
GWAS			Cardiac Troponin-T levels ( 23247143)
Protein-Protein Interactions		12 interactors: APOB ARL6 ASNA1 ATP13A2 BAG6 GET4 SEC63 SERP1 SPC25 TRAM1 UBC UBL4A	8 interactors: APP ESR1 ESR2 SEC61B TICAM1 TIRAP TRAF6 VKORC1
Entrez ID		10952	23471
HPRD ID		06715	05545
Ensembl ID		ENSG00000106803	ENSG00000067167
Uniprot IDs		P60468	G3XAN4 Q15629 Q6FHL3
PDB IDs
Enriched GO Terms of Interacting Partners?		Establishment Of Protein Localization To Membrane Membrane Organization Protein Localization To Membrane Protein Insertion Into ER Membrane Protein Localization To Organelle Establishment Of Protein Localization Protein Insertion Into Membrane Protein Localization Tail-anchored Membrane Protein Insertion Into ER Membrane Endoplasmic Reticulum Organization Transport Cellular Protein Localization Cellular Localization Protein Targeting To Membrane Endomembrane System Organization SRP-dependent Cotranslational Protein Targeting To Membrane Cotranslational Protein Targeting To Membrane Protein Targeting To ER Establishment Of Protein Localization To Endoplasmic Reticulum Protein Transport Protein Localization To Endoplasmic Reticulum Protein Targeting Multicellular Organismal Aging Organelle Organization Posttranslational Protein Targeting To Membrane, Translocation Intracellular Transport Establishment Of Protein Localization To Organelle Intracellular Protein Transport Intermembrane Transport Signal Transduction By P53 Class Mediator Internal Peptidyl-lysine Acetylation Peptidyl-lysine Acetylation Internal Protein Amino Acid Acetylation Establishment Of Localization In Cell Protein Acetylation Post-embryonic Development Glucose Metabolic Process Receptor Transactivation Cellular Response To Manganese Ion Response To Endoplasmic Reticulum Stress Posttranslational Protein Targeting To Membrane Mammary Gland Branching Involved In Thelarche Protein Catabolic Process Response To Selenium Ion Positive Regulation Of Growth Hormone Secretion Very-low-density Lipoprotein Particle Assembly Intracellular Receptor Signaling Pathway Cytoplasmic Transport Regulation Of Insulin Secretion Triglyceride Mobilization	Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Intracellular Receptor Signaling Pathway Regulation Of I-kappaB Kinase/NF-kappaB Signaling I-kappaB Kinase/NF-kappaB Signaling Regulation Of Binding Positive Regulation Of Interleukin-6 Production Positive Regulation Of Cytokine Biosynthetic Process Toll-like Receptor 4 Signaling Pathway Response To Lipid Regulation Of Interleukin-6 Production Toll-like Receptor Signaling Pathway Regulation Of Cytokine Biosynthetic Process Positive Regulation Of Lymphocyte Proliferation Cellular Response To Lipid Positive Regulation Of Mononuclear Cell Proliferation Positive Regulation Of Binding Positive Regulation Of NF-kappaB Transcription Factor Activity Vagina Development Positive Regulation Of Interleukin-6 Biosynthetic Process Uterus Development Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Activation Of Innate Immune Response Regulation Of Protein Binding Intracellular Estrogen Receptor Signaling Pathway Cellular Response To Molecule Of Bacterial Origin Regulation Of Protein Homodimerization Activity Female Genitalia Development Regulation Of Interleukin-6 Biosynthetic Process Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of Innate Immune Response Regulation Of Cell Proliferation Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Signal Transduction Regulation Of Innate Immune Response Positive Regulation Of Cellular Biosynthetic Process Prostate Gland Epithelium Morphogenesis Prostate Gland Morphogenesis Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Positive Regulation Of B Cell Proliferation Regulation Of Interferon-beta Production Innate Immune Response Positive Regulation Of Nitric Oxide Biosynthetic Process Positive Regulation Of Chemokine Production Positive Regulation Of Cell Proliferation Positive Regulation Of Reactive Oxygen Species Biosynthetic Process Organ Development Positive Regulation Of Interleukin-12 Production Positive Regulation Of Cell Activation
Tagcloud ?			3beta alleviating augmented chop contributor crosstalk droplets endoplasmic facilitating ffas fundamental g6pase gluconeogenic grp78 gsk hepg2 hfd hyperactivation initiating jnk knocking pa palmitate pepck played resident sp600125 tendency translocating
Tagcloud (Difference) ?			3beta alleviating augmented chop contributor crosstalk droplets endoplasmic facilitating ffas fundamental g6pase gluconeogenic grp78 gsk hepg2 hfd hyperactivation initiating jnk knocking pa palmitate pepck played resident sp600125 tendency translocating
Tagcloud (Intersection) ?