RALBP1 and TFPT

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		RALBP1	TFPT
Gene Name		ralA binding protein 1	TCF3 (E2A) fusion partner (in childhood Leukemia)
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol Membrane	Nucleus Nucleoplasm Nucleolus Cytoplasm Actin Filament Ino80 Complex Nuclear Membrane
	Molecular Function	GTPase Activator Activity Protein Binding ATPase Activity Ral GTPase Binding Rac GTPase Activator Activity ATPase Activity, Coupled To Movement Of Substances Rac GTPase Binding	DNA Binding Protein Binding Protein Kinase Binding Protein Heterodimerization Activity
	Biological Process	Transport Chemotaxis Signal Transduction Small GTPase Mediated Signal Transduction Metabolic Process Positive Regulation Of Rac GTPase Activity Regulation Of GTPase Activity Positive Regulation Of Cdc42 GTPase Activity Regulation Of Small GTPase Mediated Signal Transduction	DNA Repair DNA Recombination Transcription, DNA-templated Regulation Of Transcription, DNA-templated Positive Regulation Of Apoptotic Process Apoptotic Signaling Pathway
Pathways		Rho GTPase cycle Signaling by Rho GTPases
Drugs
Diseases
GWAS			Obesity-related traits ( 23251661)
Protein-Protein Interactions		27 interactors: AMOTL2 AP2M1 C1orf216 CASP8 CCNB1 CEP57 FADD GPS2 GSE1 HOOK2 HSF1 IKBKG PPL PRKCA RAC1 RALA RALB REPS1 REPS2 SMARCE1 SYNJ2BP TBRG1 TFPT TNIP1 TRAF2 ZBTB38 ZNF707	23 interactors: APP C4orf46 CCDC67 CDCA7L DYDC1 EAF1 EAF2 ELL HAUS1 KRT19 LMO2 NOL3 PAWR PIM1 RALBP1 RPGRIP1 RUNDC3A SDCCAG3 STK3 TCF3 TFIP11 TPM1 TPM3
Entrez ID		10928	29844
HPRD ID		09013	10266
Ensembl ID		ENSG00000017797	ENSG00000105619
Uniprot IDs		Q15311	P0C1Z6
PDB IDs		2KWH 2KWI
Enriched GO Terms of Interacting Partners?		Toll-like Receptor Signaling Pathway Positive Regulation Of Macrophage Differentiation Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Activation Of Innate Immune Response TRIF-dependent Toll-like Receptor Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Positive Regulation Of Innate Immune Response Toll-like Receptor 4 Signaling Pathway Neurotrophin TRK Receptor Signaling Pathway Positive Regulation Of Cellular Metabolic Process Neurotrophin Signaling Pathway TRAIL-activated Apoptotic Signaling Pathway Apoptotic Process Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Regulation Of Innate Immune Response Programmed Cell Death Regulation Of Cellular Localization Immune Response-regulating Signaling Pathway Response To External Stimulus Cell Death Death Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Kinase Activity Regulation Of Protein Localization Viral Process Negative Regulation Of Glial Cell Apoptotic Process Positive Regulation Of Myeloid Leukocyte Differentiation Positive Regulation Of Protein Metabolic Process Cellular Response To Growth Factor Stimulus Cell Surface Receptor Signaling Pathway Apoptotic Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of Immune System Process Response To Growth Factor Cellular Response To Stimulus Regulation Of Immune System Process Regulation Of Phosphorylation Positive Regulation Of Immune Response Signal Transduction Defense Response Cell Cycle Positive Regulation Of Metabolic Process Negative Regulation Of Intracellular Signal Transduction Protein Complex Assembly Response To Stress Intracellular Signal Transduction Cellular Response To Organic Substance Positive Regulation Of Myeloid Cell Differentiation	Positive Regulation Of Metabolic Process Apoptotic Process RNA Metabolic Process Positive Regulation Of Cellular Metabolic Process Programmed Cell Death Regulation Of Metabolic Process Cell Death Death Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Gene Expression Embryo Development Regulation Of Transcription, DNA-templated Actin-myosin Filament Sliding Muscle Filament Sliding Regulation Of Nucleic Acid-templated Transcription Embryonic Hemopoiesis Regulation Of RNA Biosynthetic Process Cell Differentiation Involved In Embryonic Placenta Development Regulation Of RNA Metabolic Process Regulation Of Catalytic Activity Organelle Assembly Actin-mediated Cell Contraction Cellular Component Assembly In Utero Embryonic Development Spliceosomal Complex Disassembly Response To Injury Involved In Regulation Of Muscle Adaptation Positive Regulation Of Heart Rate By Epinephrine Sarcomere Organization Regulation Of B Cell Proliferation Positive Regulation Of Macromolecule Biosynthetic Process Actin Filament-based Movement Positive Regulation Of Catalytic Activity Positive Regulation Of Transcription From RNA Polymerase II Promoter Synaptic Growth At Neuromuscular Junction Positive Regulation Of Amyloid Precursor Protein Biosynthetic Process Positive Regulation Of Cell Cycle Actin Filament-based Process Myofibril Assembly Transcription, DNA-templated Organ Development Muscle Cell Differentiation Nucleobase-containing Compound Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter During Mitosis Collateral Sprouting In Absence Of Injury Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Tissue Development Protein Stabilization Developmental Process
Tagcloud ?		abrogate complemented counteracts cytoplasmic downstream effectors equally gef hairpin kip1 lacks localization mislocalization mislocalizing murine note opposing overactivation p27 phospholipase pld1 rala ras ser thr transforming ways
Tagcloud (Difference) ?		abrogate complemented counteracts cytoplasmic downstream effectors equally gef hairpin kip1 lacks localization mislocalization mislocalizing murine note opposing overactivation p27 phospholipase pld1 rala ras ser thr transforming ways
Tagcloud (Intersection) ?