RALBP1 and AMOTL2

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		RALBP1	AMOTL2
Gene Name		ralA binding protein 1	angiomotin like 2
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol Membrane	Cytosol Tight Junction Apical Plasma Membrane Cytoplasmic Vesicle Recycling Endosome
	Molecular Function	GTPase Activator Activity Protein Binding ATPase Activity Ral GTPase Binding Rac GTPase Activator Activity ATPase Activity, Coupled To Movement Of Substances Rac GTPase Binding	Protein Binding Identical Protein Binding
	Biological Process	Transport Chemotaxis Signal Transduction Small GTPase Mediated Signal Transduction Metabolic Process Positive Regulation Of Rac GTPase Activity Regulation Of GTPase Activity Positive Regulation Of Cdc42 GTPase Activity Regulation Of Small GTPase Mediated Signal Transduction	Wnt Signaling Pathway Hippo Signaling
Pathways		Rho GTPase cycle Signaling by Rho GTPases	Signaling by Hippo
Drugs
Diseases
GWAS
Protein-Protein Interactions		27 interactors: AMOTL2 AP2M1 C1orf216 CASP8 CCNB1 CEP57 FADD GPS2 GSE1 HOOK2 HSF1 IKBKG PPL PRKCA RAC1 RALA RALB REPS1 REPS2 SMARCE1 SYNJ2BP TBRG1 TFPT TNIP1 TRAF2 ZBTB38 ZNF707	52 interactors: BLZF1 BRMS1L CARD9 CCHCR1 CDR2 CYTH4 DDIT3 DYNLL1 EIF4E2 FAM184A FXR2 GCC1 GNG11 GNG5 GOLGA2 GSTM5 KRT13 KRT15 KRT19 KRT20 KRT31 KRT38 KRTAP10-5 KRTAP4-2 LMO4 MAD1L1 MAGEA4 MAGOHB MFAP1 MPP1 MTMR6 MYO5B NDC80 NFIL3 PSMC3 RAD51D RALBP1 RASSF5 RNF20 RNF40 SH3RF2 SMARCE1 SP100 SPAG5 SPP1 THRA TMCC2 TRAF2 TRIM27 WDYHV1 ZBED1 ZGPAT
Entrez ID		10928	51421
HPRD ID		09013	16485
Ensembl ID		ENSG00000017797	ENSG00000114019
Uniprot IDs		Q15311	Q9Y2J4
PDB IDs		2KWH 2KWI
Enriched GO Terms of Interacting Partners?		Toll-like Receptor Signaling Pathway Positive Regulation Of Macrophage Differentiation Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Activation Of Innate Immune Response TRIF-dependent Toll-like Receptor Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Positive Regulation Of Innate Immune Response Toll-like Receptor 4 Signaling Pathway Neurotrophin TRK Receptor Signaling Pathway Positive Regulation Of Cellular Metabolic Process Neurotrophin Signaling Pathway TRAIL-activated Apoptotic Signaling Pathway Apoptotic Process Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Regulation Of Innate Immune Response Programmed Cell Death Regulation Of Cellular Localization Immune Response-regulating Signaling Pathway Response To External Stimulus Cell Death Death Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Kinase Activity Regulation Of Protein Localization Viral Process Negative Regulation Of Glial Cell Apoptotic Process Positive Regulation Of Myeloid Leukocyte Differentiation Positive Regulation Of Protein Metabolic Process Cellular Response To Growth Factor Stimulus Cell Surface Receptor Signaling Pathway Apoptotic Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of Immune System Process Response To Growth Factor Cellular Response To Stimulus Regulation Of Immune System Process Regulation Of Phosphorylation Positive Regulation Of Immune Response Signal Transduction Defense Response Cell Cycle Positive Regulation Of Metabolic Process Negative Regulation Of Intracellular Signal Transduction Protein Complex Assembly Response To Stress Intracellular Signal Transduction Cellular Response To Organic Substance Positive Regulation Of Myeloid Cell Differentiation	Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Biosynthetic Process Regulation Of Protein Localization Histone H2B Ubiquitination Regulation Of Cellular Localization Negative Regulation Of Gene Expression Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Protein Polyubiquitination Mitotic Cell Cycle Organelle Organization Chromosome Organization Protein Ubiquitination Histone Monoubiquitination Negative Regulation Of Viral Transcription Cell Cycle Negative Regulation Of Transcription, DNA-templated Protein Modification By Small Protein Conjugation Regulation Of Establishment Of Protein Localization Protein K63-linked Ubiquitination Histone Ubiquitination Regulation Of Transcription From RNA Polymerase II Promoter Protein Trimerization Negative Regulation Of Determination Of Dorsal Identity Regulation Of Metaphase Plate Congression Negative Regulation Of Collateral Sprouting Of Intact Axon In Response To Injury Regulation Of Protein Metabolic Process Response To Organic Substance Cellular Response To Glucagon Stimulus
Tagcloud ?		abrogate complemented counteracts cytoplasmic downstream effectors equally gef hairpin kip1 lacks localization mislocalization mislocalizing murine note opposing overactivation p27 phospholipase pld1 rala ras ser thr transforming ways	actin alanine amots angiomotin collectively consensus contain core dissociation endogenously exogenous filaments hippo hxrxxs lats1 lats2 mapping mediate members mimic negatively phospho promoted s175a s175d serine taz yap
Tagcloud (Difference) ?		abrogate complemented counteracts cytoplasmic downstream effectors equally gef hairpin kip1 lacks localization mislocalization mislocalizing murine note opposing overactivation p27 phospholipase pld1 rala ras ser thr transforming ways	actin alanine amots angiomotin collectively consensus contain core dissociation endogenously exogenous filaments hippo hxrxxs lats1 lats2 mapping mediate members mimic negatively phospho promoted s175a s175d serine taz yap
Tagcloud (Intersection) ?