RALBP1 and CEP57

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		RALBP1	CEP57
Gene Name		ralA binding protein 1	centrosomal protein 57kDa
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Gene Ontology Annotations	Cellular Component	Cytosol Membrane	Nucleus Nucleoplasm Cytoplasm Golgi Apparatus Centrosome Cytosol Microtubule Microtubule Cytoskeleton
	Molecular Function	GTPase Activator Activity Protein Binding ATPase Activity Ral GTPase Binding Rac GTPase Activator Activity ATPase Activity, Coupled To Movement Of Substances Rac GTPase Binding	Protein Binding Microtubule Binding Fibroblast Growth Factor Binding Protein Homodimerization Activity Gamma-tubulin Binding
	Biological Process	Transport Chemotaxis Signal Transduction Small GTPase Mediated Signal Transduction Metabolic Process Positive Regulation Of Rac GTPase Activity Regulation Of GTPase Activity Positive Regulation Of Cdc42 GTPase Activity Regulation Of Small GTPase Mediated Signal Transduction	Protein Import Into Nucleus, Translocation G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Organelle Organization Spermatid Development Fibroblast Growth Factor Receptor Signaling Pathway Microtubule Anchoring Protein Homooligomerization
Pathways		Rho GTPase cycle Signaling by Rho GTPases	Organelle biogenesis and maintenance Loss of proteins required for interphase microtubule organizationÂ from the centrosome Loss of Nlp from mitotic centrosomes G2/M Transition Assembly of the primary cilium Centrosome maturation Regulation of PLK1 Activity at G2/M Transition Mitotic G2-G2/M phases Anchoring of the basal body to the plasma membrane Recruitment of mitotic centrosome proteins and complexes Cell Cycle, Mitotic
Drugs
Diseases
GWAS
Protein-Protein Interactions		27 interactors: AMOTL2 AP2M1 C1orf216 CASP8 CCNB1 CEP57 FADD GPS2 GSE1 HOOK2 HSF1 IKBKG PPL PRKCA RAC1 RALA RALB REPS1 REPS2 SMARCE1 SYNJ2BP TBRG1 TFPT TNIP1 TRAF2 ZBTB38 ZNF707	15 interactors: APP CEP63 CTAGE5 FGF2 GCC1 KRT13 KRT15 KRT31 KRT40 MAGEA2B MEGF10 MYC RALBP1 TFIP11 UIMC1
Entrez ID		10928	9702
HPRD ID		09013	16261
Ensembl ID		ENSG00000017797	ENSG00000166037
Uniprot IDs		Q15311	F5GYW0 Q86XR8
PDB IDs		2KWH 2KWI	4L0R
Enriched GO Terms of Interacting Partners?		Toll-like Receptor Signaling Pathway Positive Regulation Of Macrophage Differentiation Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Activation Of Innate Immune Response TRIF-dependent Toll-like Receptor Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Positive Regulation Of Innate Immune Response Toll-like Receptor 4 Signaling Pathway Neurotrophin TRK Receptor Signaling Pathway Positive Regulation Of Cellular Metabolic Process Neurotrophin Signaling Pathway TRAIL-activated Apoptotic Signaling Pathway Apoptotic Process Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Regulation Of Innate Immune Response Programmed Cell Death Regulation Of Cellular Localization Immune Response-regulating Signaling Pathway Response To External Stimulus Cell Death Death Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Kinase Activity Regulation Of Protein Localization Viral Process Negative Regulation Of Glial Cell Apoptotic Process Positive Regulation Of Myeloid Leukocyte Differentiation Positive Regulation Of Protein Metabolic Process Cellular Response To Growth Factor Stimulus Cell Surface Receptor Signaling Pathway Apoptotic Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of Immune System Process Response To Growth Factor Cellular Response To Stimulus Regulation Of Immune System Process Regulation Of Phosphorylation Positive Regulation Of Immune Response Signal Transduction Defense Response Cell Cycle Positive Regulation Of Metabolic Process Negative Regulation Of Intracellular Signal Transduction Protein Complex Assembly Response To Stress Intracellular Signal Transduction Cellular Response To Organic Substance Positive Regulation Of Myeloid Cell Differentiation	Response To Radiation Positive Regulation Of Catalytic Activity Tissue Development Positive Regulation Of Metanephric Cap Mesenchymal Cell Proliferation Spliceosomal Complex Disassembly Growth Factor Dependent Regulation Of Skeletal Muscle Satellite Cell Proliferation Skeletal Muscle Satellite Cell Proliferation Branching Involved In Ureteric Bud Morphogenesis Positive Regulation Of Response To DNA Damage Stimulus Ureteric Bud Morphogenesis Nephron Morphogenesis Developmental Process Renal Tubule Morphogenesis Skeletal Muscle Cell Proliferation Synaptic Growth At Neuromuscular Junction Skeletal Muscle Satellite Cell Activation Fibroblast Apoptotic Process Regulation Of Catalytic Activity Renal Tubule Development Cellular Metal Ion Homeostasis Positive Regulation Of Metabolic Process Kidney Morphogenesis Histone H2A K63-linked Deubiquitination Positive Regulation Of Endothelial Cell Chemotaxis To Fibroblast Growth Factor Collateral Sprouting In Absence Of Injury Cellular Cation Homeostasis Cellular Ion Homeostasis Ureteric Bud Development Mesonephric Tubule Development Mesonephric Epithelium Development Metal Ion Homeostasis Positive Regulation Of Hydrolase Activity Cell Recognition Regulation Of Response To DNA Damage Stimulus Mesonephros Development Anatomical Structure Development Collateral Sprouting Axon Midline Choice Point Recognition Epithelium Development Regulation Of Striated Muscle Tissue Development Response To Abiotic Stimulus Notch Signaling Pathway Intracellular Signal Transduction Positive Regulation Of Cellular Protein Metabolic Process Nephron Development Response To Ionizing Radiation Positive Regulation Of DNA Metabolic Process Cellular Chemical Homeostasis Positive Regulation Of Peptidase Activity Transition Metal Ion Homeostasis
Tagcloud ?		abrogate complemented counteracts cytoplasmic downstream effectors equally gef hairpin kip1 lacks localization mislocalization mislocalizing murine note opposing overactivation p27 phospholipase pld1 rala ras ser thr transforming ways	accumulation associates cdk4 contributing cyclin d1 detail drives exit hinders import inactivation juxtanuclear maintain microtubule neoplastic nucleocytoplasmic prb prevents proliferating proper quiescence quiescent termed tlk trafficking translokin turn undue
Tagcloud (Difference) ?		abrogate complemented counteracts cytoplasmic downstream effectors equally gef hairpin kip1 lacks localization mislocalization mislocalizing murine note opposing overactivation p27 phospholipase pld1 rala ras ser thr transforming ways	accumulation associates cdk4 contributing cyclin d1 detail drives exit hinders import inactivation juxtanuclear maintain microtubule neoplastic nucleocytoplasmic prb prevents proliferating proper quiescence quiescent termed tlk trafficking translokin turn undue
Tagcloud (Intersection) ?