RALBP1 and ZNF707

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid, two hybrid)

		RALBP1	ZNF707
Description		ralA binding protein 1	zinc finger protein 707
Image			No pdb structure
GO Annotations	Cellular Component	Spindle Pole Nucleus Nucleoplasm Cytoplasm Mitochondrion Cytosol Cytoskeleton Plasma Membrane Membrane Nuclear Body	Nucleus
	Molecular Function	Nucleotide Binding GTPase Activator Activity Protein Binding ATP Binding ABC-type Xenobiotic Transporter Activity ABC-type Glutathione S-conjugate Transporter Activity Transmembrane Transporter Activity Small GTPase Binding ATPase-coupled Transmembrane Transporter Activity Xenobiotic Transmembrane Transporter Activity	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA Binding DNA-binding Transcription Factor Activity Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	Positive Regulation Of Protein Phosphorylation Receptor-mediated Endocytosis Chemotaxis Signal Transduction Small GTPase-mediated Signal Transduction Regulation Of Cdc42 Protein Signal Transduction Regulation Of GTPase Activity Positive Regulation Of GTPase Activity Regulation Of Small GTPase Mediated Signal Transduction Transmembrane Transport Positive Regulation Of Mitochondrial Fission Doxorubicin Transport Xenobiotic Detoxification By Transmembrane Export Across The Plasma Membrane	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II
Pathways		CDC42 GTPase cycle RAC1 GTPase cycle	Generic Transcription Pathway
Drugs
Diseases
GWAS		LDL cholesterol ( 30275531)
Interacting Genes		46 interacting genes: AMOTL2 AP2M1 C1orf216 CASP8 CBY1 CCDC13 CCDC136 CCDC88B CCHCR1 CCNB1 CEP57 CREBZF DLG4 DRC4 FADD GSE1 HOOK2 HSF1 HSPA13 IKBKG ITSN1 KANK2 LDOC1 MSANTD4 PCM1 PLCG2 PPP1R13B PRKCA RAC1 RALA RALB REPS1 REPS2 RHOU SAPCD2 SMARCE1 SYCE1 SYNJ2BP TBRG1 TCP10L TNIP1 TP53BP2 TRAF2 TSFM ZBTB38 ZNF707	8 interacting genes: CASP8 CCNDBP1 KRTAP10-5 KRTAP10-7 MDFI NDEL1 RALBP1 STX1A
Entrez ID		10928	286075
HPRD ID		09013	14162
Ensembl ID		ENSG00000017797	ENSG00000181135
Uniprot IDs		Q15311	Q96C28
PDB IDs		2KWH 2KWI 2MBG 6ZQT 6ZRN
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Macrophage Differentiation Regulation Of Macrophage Differentiation Regulation Of Endocytosis Protein-macromolecule Adaptor Activity Intracellular Signaling Cassette Endocytosis Cellular Component Assembly Protein Binding Intracellular Signal Transduction Positive Regulation Of Immune System Process Regulation Of Vesicle-mediated Transport Cytosol Positive Regulation Of Execution Phase Of Apoptosis Positive Regulation Of Myeloid Leukocyte Differentiation Regulation Of Receptor-mediated Endocytosis Protein Kinase Binding Cytoplasmic Microtubule Organization Import Into Cell Death Effector Domain Binding Regulation Of Signal Transduction Centrosome Regulation Of Receptor Internalization Protein-containing Complex Organization Tumor Necrosis Factor Receptor Binding Ripoptosome CD95 Death-inducing Signaling Complex Protein-containing Complex Assembly Cell Death Response To Lipopolysaccharide Death-inducing Signaling Complex Positive Regulation Of Leukocyte Differentiation Ubiquitin Protein Ligase Binding Programmed Cell Death Identical Protein Binding Positive Regulation Of Cellular Component Organization Tumor Necrosis Factor Receptor Superfamily Binding Positive Regulation Of Cell Communication Positive Regulation Of Signaling Positive Regulation Of Myeloid Cell Differentiation Microtubule Cytoskeleton Organization Regulation Of Canonical NF-kappaB Signal Transduction Organelle Organization Apoptotic Signaling Pathway Positive Regulation Of Peptide Hormone Secretion TRAIL-activated Apoptotic Signaling Pathway Response To Molecule Of Bacterial Origin Positive Regulation Of Signal Transduction Positive Regulation Of Peptide Secretion Cytoskeleton Organization Regulation Of Cytokine Production	Identical Protein Binding Cell Differentiation Involved In Embryonic Placenta Development Synaptic Vesicle SNAP Receptor Activity SNARE Complex Myosin Head/neck Binding SNARE Binding Vesicle Docking Doxorubicin Transport Organelle Localization By Membrane Tethering Syncytiotrophoblast Cell Differentiation Involved In Labyrinthine Layer Development Organelle Membrane Fusion Organelle Localization Membrane Docking Vesicle Fusion Positive Regulation Of Norepinephrine Secretion Synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II Complex Positive Regulation Of GTPase Activity Positive Regulation Of Hydrolase Activity Neurofilament Cytoskeleton Keratin Filament Death Effector Domain Binding Synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I Complex Synaptobrevin 2-SNAP-25-syntaxin-1a Complex Organelle Fusion Regulation Of GTPase Activity
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