FAM156B and CRACR2A

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		FAM156B	CRACR2A
Description		family with sequence similarity 156 member B	calcium release activated channel regulator 2A
Image		No pdb structure
GO Annotations	Cellular Component	Nuclear Envelope Membrane	Golgi Membrane Immunological Synapse Extracellular Region Cytoplasm Golgi Apparatus Microtubule Organizing Center Cytoskeleton Plasma Membrane Membrane Vesicle Trans-Golgi Network Membrane Weibel-Palade Body Specific Granule Lumen Specific Granule
	Molecular Function	Protein Binding	Nucleotide Binding GTPase Activity G Protein Activity Calcium Ion Binding Protein Binding GTP Binding Hydrolase Activity Metal Ion Binding
	Biological Process		Store-operated Calcium Entry Adaptive Immune Response Immune System Process Monoatomic Ion Transport Calcium Ion Transport Intracellular Protein Localization Vesicle-mediated Transport Endosomal Transport Activation Of Store-operated Calcium Channel Activity Response To Histamine T-helper 1 Cell Differentiation Positive Regulation Of JNK Cascade Positive Regulation Of Calcium Ion Transport
Pathways			Neutrophil degranulation
Drugs
Diseases
GWAS			Femur bone mineral density x serum urate levels interaction ( 34046847) Severe insulin-deficient type 2 diabetes ( 34737425)
Interacting Genes		2 interacting genes: CRACR2A GADD45G	35 interacting genes: ANKRD29 ASB3 ATN1 CCHCR1 CDC23 DDIT3 FAM156A FAM156B FAM86C1P FKBP6 GIGYF1 GOLGA2 KRT31 KRT75 KRTAP13-1 KRTAP19-5 LRIF1 MDFI MID2 MKRN3 NOTCH2NLA OIP5 PNMA5 POLR1C RBAK RORB SLAIN1 SORBS3 TLE5 TRAF1 TRIM29 USP2 ZC2HC1C ZNF20 ZNF655
Entrez ID		727866	84766
HPRD ID			10079
Ensembl ID		ENSG00000179304	ENSG00000130038
Uniprot IDs		Q8NDB6	Q9BSW2
PDB IDs			6PSD
Enriched GO Terms of Interacting Partners?		Positive Regulation Of JNK Cascade Regulation Of JNK Cascade Positive Regulation Of MAPK Cascade Activation Of Store-operated Calcium Channel Activity Positive Regulation Of Store-operated Calcium Channel Activity Weibel-Palade Body Store-operated Calcium Entry Response To Histamine Regulation Of MAPK Cascade Specific Granule T-helper 1 Cell Differentiation Positive Regulation Of Cation Channel Activity Positive Regulation Of P38MAPK Cascade Positive Regulation Of Intracellular Signal Transduction Regulation Of P38MAPK Cascade T Cell Differentiation Involved In Immune Response Positive Regulation Of Ion Transmembrane Transporter Activity T-helper Cell Differentiation Immunological Synapse Positive Regulation Of Transporter Activity CD4-positive, Alpha-beta T Cell Differentiation Specific Granule Lumen CD4-positive, Alpha-beta T Cell Activation Positive Regulation Of Signal Transduction T Cell Activation Involved In Immune Response Alpha-beta T Cell Differentiation G Protein Activity Positive Regulation Of Cell Communication Positive Regulation Of Signaling Positive Regulation Of Cold-induced Thermogenesis Microtubule Organizing Center Regulation Of Transmembrane Transporter Activity Alpha-beta T Cell Activation Positive Regulation Of Calcium Ion Transport Regulation Of Monoatomic Ion Transmembrane Transporter Activity Trans-Golgi Network Membrane Regulation Of Intracellular Signal Transduction Positive Regulation Of Cation Transmembrane Transport Lymphocyte Activation Involved In Immune Response Positive Regulation Of Monoatomic Ion Transmembrane Transport Regulation Of Cold-induced Thermogenesis Leukocyte Activation Involved In Immune Response T Cell Differentiation Cell Activation Involved In Immune Response Cell Differentiation	Identical Protein Binding
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